AT5G23720.2
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:nucleus 0.995 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : dual specificity protein phosphatase family protein | ||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes a protein tyrosine phosphatase Propyzamide-Hypersensitive 1 (PHS1). One of the mutant alleles, phs1-1, is hypersensitive to the microtubule-destabilizing drug propyzamide, suggesting that PHS1 may be involved in phosphorylation cascades that control the dynamics of cortical microtubules in plant cells. A second allele, phs1-3, is hypersensitive to abscisic acid, indicating a possible involvement of PHS1 in ABA signalling. | ||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
PROPYZAMIDE-HYPERSENSITIVE 1 (PHS1); FUNCTIONS IN: protein tyrosine/serine/threonine phosphatase activity, phosphoprotein phosphatase activity; INVOLVED IN: cortical microtubule organization, regulation of gene expression, response to abscisic acid stimulus, regulation of stomatal movement; LOCATED IN: cytoplasm; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protein-tyrosine phosphatase, active site (InterPro:IPR016130), Dual-specific/protein-tyrosine phosphatase, conserved region (InterPro:IPR000387), Actin-fragmin kinase, catalytic (InterPro:IPR015275), Dual specificity phosphatase, catalytic domain (InterPro:IPR000340), Dual specificity phosphatase, subgroup, catalytic domain (InterPro:IPR020422), Protein kinase-like domain (InterPro:IPR011009); BEST Arabidopsis thaliana protein match is: dual specificity protein phosphatase 1 (TAIR:AT3G23610.2); Has 3732 Blast hits to 3722 proteins in 327 species: Archae - 11; Bacteria - 92; Metazoa - 2029; Fungi - 326; Plants - 343; Viruses - 172; Other Eukaryotes - 759 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr5:+:7998816..8002594 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 94596.10 Da | ||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 6.40 | ||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.56 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 845 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MIWSLGERNT DPKSPPSRQS SEISLWERLG KASTVDIDSS CFSWNMLSSL HHTEHSSSTD HSEEDQSKPL EVTVNSGGVV FFALFNSSSS EDASRKEEAA 101: VIKFASSRMA TQSERLGYEF SKWLGVQIPQ ARVIHSCNPE WTLIKEATEK AQAKATSEGD EVGEMTCSEL LEALELSRCL LLMSYVHGCP MLESMSSFET 201: EEKAERAAAA LGRILVLDLV IRNEDRLPCR QLRWRGNPAN LLLTDRIVSS AKHHECSFDE AFDSAIKRYH PKDYRSIQRE RRASSVDSRS RLSISDQMLV 301: SQASDFSDIT ESPRSYDTGL MSPMSDRSVA ADFHLVAIDS GVPRRPPAGK RASDQEIYPR LVELLLNSSQ YSSNLLHEIT EGSLGYPQAE DGEETSNVRS 401: VVTPVVREFR NGFRAGLRDL QEFHIFLVTL HQKLDVLLRA FFSMMDKTMC ADFDREDFAV PESPSHTHGH EVNHYPSPSK DRVPSDNSSD HSESDMQKSV 501: PRTPNSENKE DGSSPKSRES WHGRSGKGGE SLSSQRLAAK LRDFHKFAKV DAESNKELDQ WNETLRNEVM KLCQENGFNT GFFEGSDNNS CTDAYELKVR 601: LEHILERISL ISKAANTEKP SMIQENLFIG GGLAARSIYT LQHLGITHVL CLCANEIGQS DTQYPDLFEY QNFSITDDED SNIESIFQEA LDFIKHGEET 701: GGKILVHCFE GRSRSATVVL AYLMLQKKLT LLEAWSKLRK VHRRAQPNDG FARILINLDK KCHGKVSMEW RQRKPTMKVC PVCGKNAGLS SSSLKLHLQK 801: SHRKLSSGSV DSAMNMEIQK ALEALKLSTG RGSSASSNSF QSHPG |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)