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AT3G63280.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
cytosol 0.940
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : NIMA-related kinase 4
Curator
Summary (TAIR10)
Encodes AtNek4, a member of the NIMA-related serine/threonine kinases (Neks) that have been linked to cell-cycle regulation in fungi and mammals. Plant Neks might be involved in plant development processes.
Computational
Description (TAIR10)
NIMA-related kinase 4 (NEK4); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: cellular_component unknown; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: NIMA-related kinase 2 (TAIR:AT3G04810.2); Has 126311 Blast hits to 124068 proteins in 4177 species: Archae - 117; Bacteria - 14403; Metazoa - 46720; Fungi - 12754; Plants - 30797; Viruses - 521; Other Eukaryotes - 20999 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT3G63280-MONOMERBioCyc:ARA:GQT-965-MONOMERBioGrid:10817EC:2.7.11.1
eggNOG:ENOG410Y7JFeggNOG:KOG0589EMBL:AL138648EMBL:AY080682
EMBL:AY117234EMBL:CP002686EnsemblPlants:AT3G63280EnsemblPlants:AT3G63280.1
EnsemblPlants:AT3G63280.2entrez:825503GeneID:825503GO:GO:0004674
GO:GO:0005524GO:GO:0006468Gramene:AT3G63280.1Gramene:AT3G63280.2
hmmpanther:PTHR24362hmmpanther:PTHR24362:SF218HOGENOM:HOG000238503InParanoid:Q8RXT4
InterPro:IPR000719InterPro:IPR008271InterPro:IPR011009InterPro:IPR017441
iPTMnet:Q8RXT4KEGG:ath:AT3G63280KO:K08857OMA:NQNRETA
PaxDb:Q8RXT4Pfam:PF00069Pfam:Q8RXT4Pfscan:PS50011
PhylomeDB:Q8RXT4PIR:T48117PRIDE:Q8RXT4PRO:PR:Q8RXT4
PROSITE:PS00107PROSITE:PS00108PROSITE:PS50011ProteinModelPortal:Q8RXT4
Proteomes:UP000006548Reactome:R-ATH-179409RefSeq:NP_001118899.1RefSeq:NP_191887.2
scanprosite:PS00107scanprosite:PS00108SMART:SM00220SMR:Q8RXT4
SUPFAM:SSF56112TAIR:AT3G63280tair10-symbols:ATNEK4tair10-symbols:NEK4
UniGene:At.33963UniProt:Q8RXT4
Coordinates (TAIR10) chr3:+:23378582..23381362
Molecular Weight (calculated) 62901.30 Da
IEP (calculated) 9.43
GRAVY (calculated) -0.54
Length 555 amino acids
Sequence (TAIR10)
(BLAST)
001: MERYEVLEQI GKGSFGSALL VRHKQERKKY VLKKIRLARQ SDRARRSAHQ EMELISTVRN PFVVEYKDSW VEKGCYVCIV IGYCQGGDMT DTIKRACGVH
101: FPEEKLCQWL VQLLMALDYL HSNHILHRDV KCSNIFLTKE QDIRLGDFGL AKILTSDDLT SSVVGTPSYM CPELLADIPY GSKSDIWSLG CCMYEMAAHK
201: PPFKASDVQT LITKIHKLIM DPIPAMYSGS FRGLIKSMLR KNPELRPSAN ELLNHPHLQP YISMVYMKLE SPRRSTFPLQ FSERDATLKE RRRSSFSNDR
301: RLNPSVSDTE AGSVSSSGKA SPTPMFNGRK VSEVTVGVVR EEIVPQRQEE AKKQSGAART PRVAGTSAKA STQRTVFKHE LMKVSNPTER RRRVSLPLVV
401: ENPYTYESDI TALCSLNSPD VSVNTPRFDK IAEFPEDIFQ NQNRETASRR EVARHSFSSP PCPPHGEDNS NGSITKDKCT VQKRSVSEVK QRRFDTSSYQ
501: QRAEALEGLL EFSAKLLQQE RYDELGVLLK PFGAERVSSR ETAIWLTKSF KEASV
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)