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AT3G60240.4
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 0.673
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31615849 (2019): plastid plastid thylakoid
  • PMID:24134884 (2013): cytoskeleton microtubules
  • PMID:22318864 (2012): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : eukaryotic translation initiation factor 4G
Curator
Summary (TAIR10)
protein synthesis initiation factor 4G (EIF4G). A mutation in this gene (cum2-1) results in decreased accumulation of CMV coat protein in upper, uninoculated leaves. Likely affects cell-to-cell movement of the virus, also affects TCV multiplication.
Computational
Description (TAIR10)
eukaryotic translation initiation factor 4G (EIF4G); FUNCTIONS IN: translation initiation factor activity; INVOLVED IN: response to virus; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Initiation factor eIF-4 gamma, MA3 (InterPro:IPR003891), Armadillo-type fold (InterPro:IPR016024), MIF4G-like, type 3 (InterPro:IPR003890), MIF4-like, type 1/2/3 (InterPro:IPR016021); BEST Arabidopsis thaliana protein match is: MIF4G domain-containing protein / MA3 domain-containing protein (TAIR:AT5G57870.1); Has 9538 Blast hits to 7052 proteins in 555 species: Archae - 16; Bacteria - 1070; Metazoa - 4140; Fungi - 1856; Plants - 683; Viruses - 80; Other Eukaryotes - 1693 (source: NCBI BLink).
Protein Annotations
BioGrid:10508eggNOG:ENOG410IPIBeggNOG:ENOG410ZIZBEMBL:AB107249
EMBL:AF263518EMBL:AF263834EMBL:AK226781EMBL:AL163852
EMBL:CP002686EnsemblPlants:AT3G60240EnsemblPlants:AT3G60240.4entrez:825194
ExpressionAtlas:Q76E23Gene3D:1.25.40.180GeneID:825194Genevisible:Q76E23
GO:GO:0003743GO:GO:0006417GO:GO:0009615GO:GO:0009737
hmmpanther:PTHR23253hmmpanther:PTHR23253:SF26HOGENOM:HOG000015159InParanoid:Q76E23
InterPro:IPR003890InterPro:IPR003891InterPro:IPR016021InterPro:IPR016024
iPTMnet:Q76E23MINT:MINT-8069839ncoils:CoilOMA:DENEIGM
PaxDb:Q76E23Pfam:PF02847Pfam:PF02854Pfam:Q76E23
Pfscan:PS51366PhylomeDB:Q76E23PIR:T49219PRIDE:Q76E23
PRO:PR:Q76E23PROSITE:PS51366ProteinModelPortal:Q76E23Proteomes:UP000006548
RefSeq:NP_001078318.1RefSeq:NP_001078319.1SMART:SM00543SMART:SM00544
STRING:3702.AT3G60240.4SUPFAM:SSF48371SUPFAM:SSF81995TAIR:AT3G60240
tair10-symbols:CUM2tair10-symbols:EIF4GUniGene:At.46412UniProt:Q76E23
Coordinates (TAIR10) chr3:+:22261842..22268295
Molecular Weight (calculated) 187932.00 Da
IEP (calculated) 7.77
GRAVY (calculated) -0.74
Length 1727 amino acids
Sequence (TAIR10)
(BLAST)
0001: MSYNQSRPDR SETQYRRTGR STGNQQQQQQ HRSSSAAGYG KGAGAPGSAP APSTYPDNSS LSSNRSFKKP GNAQGGGQPR VNLPPVNHPN NHNNGPNAHS
0101: RSQVTGEPGV GGPTNPTESF NRNTGPIPKA PTSQSTVMSS KINETPNTAK VAASGDASQA FPLQFGSLGP DLMVPARTTS APPNMDDQKR AQMQQSSLRT
0201: ASNVPASVPK KDSSNKGADN QLMRKEGHNP SSEKADIQVP HIAPPSQTQK SPITNIRMPS VQTPYQHTQV PHPVHFGGPN MHMQTPVTAT SFQMPMPMAL
0301: SMGNTPQIPP QVFYQGHPPH PMHHQGMMHQ AQGHGFATPM GAQIHPQLGH VGVGLSPQYP QQQGGKYGGA RKTTPVKITH PDTHEELRLD RRGDPYSEGD
0401: STALKPHSNP PPRSQPVSSF APRPVNLVQP SYNSNTMIYP PVSVPLNNGP MSSAQAPRYH YPVIDGSQRV QLINQPAHTA PQLIRPAAPA HLSSDSTSSV
0501: KARNAQNVMS SALPVNAKVS VKPAGVSEKL GSPKDRSHGE VNISLSQKNV EACSLSSSQQ PKPSFVSGVP NSSAPPAKSP VETVPLAKSS VETVPPVKSS
0601: VETAPVTTTE IRRAEMVSES ISVEDQTCKV EPPHNLTENR GQTMPDSLVS DPETATVAAK ENLSLPATNG FRKQLLKVST TSDAPTSDSV DTSIDKSTEG
0701: SSHASSEISG SSPQEKDLKC DNRTASDKLD ERSVISDAKH ETLSGVLEKA QNEVDGATDV CPVSEKLAVT DDTSSDLPHS THVLSSTVPL GHSETHKSAV
0801: ETNTRRNTST KGKKKIKEIL QKADAAGTTS DLYMAYKGPE EKKESSNVVH DVSNQNLLPA IPQAVEAIVD TEPVKNEPED WEDAADVSTP KLETADNSVN
0901: AKRGSSDEVS DNCINTEKKY SRDFLLKFAD LCTALPEGFD VSPDIANALI VAYMGASHHE HDSYPTPGKV MDRQASGARL DRRPSNVAGD DRWTKNQGSL
1001: PAGYGGNVGF RPGQGGNSGV LRNPRMQGPI ISRPMQPVGP MGGMGRNTPD LERWQRGSNF QQKGLFPSPH TPMQVMHKAE RKYQVGTIAD EEQAKQRQLK
1101: SILNKLTPQN FEKLFEQVKS VNIDNAVTLS GVISQIFDKA LMEPTFCEMY ADFCFHLSGA LPDFNENGEK ITFKRLLLNK CQEEFERGEK EEEEASRVAE
1201: EGQVEQTEEE REEKRLQVRR RMLGNIRLIG ELYKKRMLTE KIMHACIQKL LGYNQDPHEE NIEALCKLMS TIGVMIDHNK AKFQMDGYFE KMKMLSCKQE
1301: LSSRVRFMLI NAIDLRKNKW QERMKVEGPK KIEEVHRDAA QERQTQANRL SRGPSMNSSG RRGHMEFSSP RGGGGMLSPP AAQMGSYHGP PQGRGFSNQD
1401: IRFDDRPSYE PRMVPMPQRS VCEEPITLGP QGGLGQGMSI RRPAVASNTY QSDATQAGGG DSRRPAGGLN GFGSHRPASP VTHGRSSPQE RGTAYVHREF
1501: ASLSRASDLS PEVSSARQVL QGPSATVNSP RENALSEEQL ENLSLSAIKE YYSARDENEI GMCMKDMNSP AYHPTMISLW VTDSFERKDK ERDLLAKLLV
1601: NLVKSADNAL NEVQLVKGFE SVLKTLEDAV NDAPKAAEFL GRIFGKSVTE KVVTLTEIGR LIQEGGEEPG SLIEFGLGGD VLGSVLEMIK TEAGEETLVE
1701: IRRSSGLRIE NFKPHAPNRS KILEKFT
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)