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AT3G60240.2
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 0.999
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:30961429 (2019): nucleus
  • PMID:22550958 (2012): plastid
  • PMID:21533090 (2011): extracellular region plant-type cell wall
  • PMID:21433285 (2011): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : eukaryotic translation initiation factor 4G
Curator
Summary (TAIR10)
protein synthesis initiation factor 4G (EIF4G). A mutation in this gene (cum2-1) results in decreased accumulation of CMV coat protein in upper, uninoculated leaves. Likely affects cell-to-cell movement of the virus, also affects TCV multiplication.
Computational
Description (TAIR10)
eukaryotic translation initiation factor 4G (EIF4G); FUNCTIONS IN: translation initiation factor activity; INVOLVED IN: response to virus; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Initiation factor eIF-4 gamma, MA3 (InterPro:IPR003891), Armadillo-type fold (InterPro:IPR016024), MIF4G-like, type 3 (InterPro:IPR003890), MIF4-like, type 1/2/3 (InterPro:IPR016021); BEST Arabidopsis thaliana protein match is: MIF4G domain-containing protein / MA3 domain-containing protein (TAIR:AT2G24050.1); Has 9534 Blast hits to 6973 proteins in 578 species: Archae - 16; Bacteria - 1115; Metazoa - 4280; Fungi - 1919; Plants - 715; Viruses - 78; Other Eukaryotes - 1411 (source: NCBI BLink).
Protein Annotations
eggNOG:ENOG410IPIBeggNOG:ENOG410ZIZBEMBL:CP002686EnsemblPlants:AT3G60240
EnsemblPlants:AT3G60240.2entrez:825194ExpressionAtlas:A8MR97Gene3D:1.25.40.180
GeneID:825194GO:GO:0003743Gramene:AT3G60240.2hmmpanther:PTHR23253
hmmpanther:PTHR23253:SF26HOGENOM:HOG000015159InterPro:IPR003890InterPro:IPR003891
InterPro:IPR016021InterPro:IPR016024iPTMnet:A8MR97KEGG:ath:AT3G60240
KO:K03260ncoils:CoilPaxDb:A8MR97Pfam:PF02847
Pfam:PF02854Pfscan:PS51366PhylomeDB:A8MR97PRIDE:A8MR97
PROSITE:PS51366ProteinModelPortal:A8MR97Proteomes:UP000006548RefSeq:NP_001078317.1
SMART:SM00543SMART:SM00544SMR:A8MR97STRING:3702.AT3G60240.4
SUPFAM:SSF48371SUPFAM:SSF81995TAIR:AT3G60240tair10-symbols:CUM2
tair10-symbols:EIF4GUniGene:At.46412UniProt:A8MR97
Coordinates (TAIR10) chr3:+:22261842..22268295
Molecular Weight (calculated) 187561.00 Da
IEP (calculated) 7.77
GRAVY (calculated) -0.75
Length 1723 amino acids
Sequence (TAIR10)
(BLAST)
0001: MSYNQSRPDR SETQYRRTGR STGNQQQQQQ HRSSSAAGYG KGAGAPGSAP APSTYPDNSS LSSNRSFKKP GNAQGGGQPR VNLPPVNHPN NHNNGPNAHS
0101: RSQGEPGVGG PTNPTESFNR NTGPIPKAPT SQSTVMSSKI NETPNTAKAS GDASQAFPLQ FGSLGPDLMV PARTTSAPPN MDDQKRAQMQ QSSLRTASNV
0201: PASVPKKDSS NKGADNQLMR KEGHNPSSEK ADIQVPHIAP PSQTQKSPIT NIRMPSVQTP YQHTQVPHPV HFGGPNMHMQ TPVTATSFQM PMPMALSMGN
0301: TPQIPPQVFY QGHPPHPMHH QGMMHQAQGH GFATPMGAQI HPQLGHVGVG LSPQYPQQQG GKYGGARKTT PVKITHPDTH EELRLDRRGD PYSEGDSTAL
0401: KPHSNPPPRS QPVSSFAPRP VNLVQPSYNS NTMIYPPVSV PLNNGPMSSA QAPRYHYPVI DGSQRVQLIN QPAHTAPQLI RPAAPAHLSS DSTSSVKARN
0501: AQNVMSSALP VNAKVSVKPA GVSEKLGSPK DRSHGEVNIS LSQKNVEACS LSSSQQPKPS FVSGVPNSSA PPAKSPVETV PLAKSSVETV PPVKSSVETA
0601: PVTTTEIRRA EMVSESISVE DQTCKVEPPH NLTENRGQTM PDSLVSDPET ATVAAKENLS LPATNGFRKQ LLKVSTTSDA PTSDSVDTSI DKSTEGSSHA
0701: SSEISGSSPQ EKDLKCDNRT ASDKLDERSV ISDAKHETLS GVLEKAQNEV DGATDVCPVS EKLAVTDDTS SDLPHSTHVL SSTVPLGHSE THKSAVETNT
0801: RRNTSTKGKK KIKEILQKAD AAGTTSDLYM AYKGPEEKKE SSNVVHDVSN QNLLPAIPQA VEAIVDTEPV KNEPEDWEDA ADVSTPKLET ADNSVNAKRG
0901: SSDEVSDNCI NTEKKYSRDF LLKFADLCTA LPEGFDVSPD IANALIVAYM GASHHEHDSY PTPGKVMDRQ ASGARLDRRP SNVAGDDRWT KNQGSLPAGY
1001: GGNVGFRPGQ GGNSGVLRNP RMQGPIISRP MQPVGPMGGM GRNTPDLERW QRGSNFQQKG LFPSPHTPMQ VMHKAERKYQ VGTIADEEQA KQRQLKSILN
1101: KLTPQNFEKL FEQVKSVNID NAVTLSGVIS QIFDKALMEP TFCEMYADFC FHLSGALPDF NENGEKITFK RLLLNKCQEE FERGEKEEEE ASRVAEEGQV
1201: EQTEEEREEK RLQVRRRMLG NIRLIGELYK KRMLTEKIMH ACIQKLLGYN QDPHEENIEA LCKLMSTIGV MIDHNKAKFQ MDGYFEKMKM LSCKQELSSR
1301: VRFMLINAID LRKNKWQERM KVEGPKKIEE VHRDAAQERQ TQANRLSRGP SMNSSGRRGH MEFSSPRGGG GMLSPPAAQM GSYHGPPQGR GFSNQDIRFD
1401: DRPSYEPRMV PMPQRSVCEE PITLGPQGGL GQGMSIRRPA VASNTYQSDA TQAGGGDSRR PAGGLNGFGS HRPASPVTHG RSSPQERGTA YVHREFASLS
1501: RASDLSPEVS SARQVLQGPS ATVNSPRENA LSEEQLENLS LSAIKEYYSA RDENEIGMCM KDMNSPAYHP TMISLWVTDS FERKDKERDL LAKLLVNLVK
1601: SADNALNEVQ LVKGFESVLK TLEDAVNDAP KAAEFLGRIF GKSVTEKVVT LTEIGRLIQE GGEEPGSLIE FGLGGDVLGS VLEMIKTEAG EETLVEIRRS
1701: SGLRIENFKP HAPNRSKILE KFT
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)