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AT2G46450.2
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plasma membrane 0.805
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : cyclic nucleotide-gated channel 12
Curator
Summary (TAIR10)
Member of Cyclic nucleotide gated channel family.Positive regulator of resistance against avirulent fungal pathogen.Suppresses the phenotype conferred by cpr22 in a dosage-dependent manner.
Computational
Description (TAIR10)
cyclic nucleotide-gated channel 12 (CNGC12); CONTAINS InterPro DOMAIN/s: Cyclic nucleotide-binding (InterPro:IPR000595), Cyclic nucleotide-binding-like (InterPro:IPR018490), Ion transport (InterPro:IPR005821), RmlC-like jelly roll fold (InterPro:IPR014710), IQ calmodulin-binding region (InterPro:IPR000048); BEST Arabidopsis thaliana protein match is: cyclic nucleotide-gated channels (TAIR:AT2G46440.1).
Protein Annotations
eggNOG:ENOG410XPSEeggNOG:KOG0498EMBL:CP002685EnsemblPlants:AT2G46450
EnsemblPlants:AT2G46450.2entrez:819253ExpressionAtlas:F4II92Gene3D:2.60.120.10
GeneID:819253GO:GO:0005216GO:GO:0016021Gramene:AT2G46450.2
hmmpanther:PTHR10217hmmpanther:PTHR10217:SF465InterPro:IPR000048InterPro:IPR000595
InterPro:IPR005821InterPro:IPR014710InterPro:IPR018490PaxDb:F4II92
Pfam:PF00520Pfscan:PS50042Pfscan:PS50096PROSITE:PS50042
PROSITE:PS50096ProteinModelPortal:F4II92Proteomes:UP000006548RefSeq:NP_001189759.1
SMART:SM00100SMR:F4II92STRING:3702.AT2G46450.1SUPFAM:SSF51206
SUPFAM:SSF81324TAIR:AT2G46450tair10-symbols:CNGC12TMHMM:TMhelix
UniGene:At.36508UniGene:At.50596UniProt:F4II92
Coordinates (TAIR10) chr2:+:19065845..19068364
Molecular Weight (calculated) 71992.90 Da
IEP (calculated) 9.93
GRAVY (calculated) -0.11
Length 626 amino acids
Sequence (TAIR10)
(BLAST)
001: MNHRRSKFAR IDSMGVDGKL KSVRGRLKKV YGKMKTLENW RKTVLLACVV ALAIDPLFLF IPLIDSQRFC FTFDKTLVAV TIAPRSQASL RGEIVVHSKA
101: TLKTRLLFHF IVDIISVLPI PQVVVLTLIP LSASLVSERI LKWIILSQYV PRIIRMYPLY KEVTRAFGTV AESKWAGAAL NLFLYMLHSY VFGAFWYLSS
201: IERKSKCWRA ACARTSDCNL TVTDLLCKRA GSDNIRFLNT SCPLIDPAQI TNSTDFDFGM YIDALKSGVL EVKPKDFPRK FVYCFWWGLR NISALGQNLE
301: TSNSAGEIFF AIIICVSGLL LFAVLIGNVQ KYLQSSTTRV DEMEEKRRDT EKWMSYRVIP EYLKERIRRF EDYKWRETKG TEEEALLRSL PKDLRLETKR
401: YLYLDMLKRV PWLNIMDDGW LLEAVCDRVK SVFYLANSFI VREGHPVEEM LIVTRGKLKS TTGSHEMGVR NNCCDLQDGD ICGELLFNGS RLPTSTRTVM
501: TLTEVEGFIL LPDDIKFIAS HLNVFQRQKL QRTFRLYSQQ WRSWAAFFIQ AAWRKHCKRK LSKTRDNENI PQGTQLNLAS TLYVSRFVSK ALQNRRKDTA
601: DCSSSPDMSP PVPHKPADLE FAKAEA
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)