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AT4G09140.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : MUTL-homologue 1
Curator
Summary (TAIR10)
Encodes a protein with similarity to Mut1 DNA mismatch repair protein, from E.coli. The protein is expressed during prophase I of meiosis, colocalizes with MLH3 throughout pachytene and is dependent on MLH3 for proper localization.
Computational
Description (TAIR10)
MUTL-homologue 1 (MLH1); FUNCTIONS IN: protein binding, bridging; INVOLVED IN: in 6 processes; LOCATED IN: nuclear chromatin; EXPRESSED IN: 14 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: DNA mismatch repair protein Mlh1 (InterPro:IPR011186), DNA mismatch repair, conserved site (InterPro:IPR014762), ATPase-like, ATP-binding domain (InterPro:IPR003594), DNA mismatch repair protein, C-terminal (InterPro:IPR013507), DNA mismatch repair protein, N-terminal (InterPro:IPR014763), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568), DNA mismatch repair protein (InterPro:IPR002099), Ribosomal protein S5 domain 2-type fold, subgroup (InterPro:IPR014721); BEST Arabidopsis thaliana protein match is: DNA mismatch repair protein, putative (TAIR:AT4G02460.1); Has 6802 Blast hits to 6727 proteins in 2342 species: Archae - 68; Bacteria - 4480; Metazoa - 469; Fungi - 496; Plants - 114; Viruses - 0; Other Eukaryotes - 1175 (source: NCBI BLink).
Protein Annotations
eggNOG:COG0323eggNOG:KOG1979EMBL:AC005359EMBL:AF072897
EMBL:AF360278EMBL:AJ012747EMBL:AL161514EMBL:CP002687
EnsemblPlants:AT4G09140EnsemblPlants:AT4G09140.1entrez:826493Gene3D:3.30.230.10
Gene3D:3.30.565.10GeneID:826493Genevisible:Q9ZRV4GO:GO:0000790
GO:GO:0000795GO:GO:0003697GO:GO:0005524GO:GO:0005712
GO:GO:0006298GO:GO:0006312GO:GO:0009555GO:GO:0009845
GO:GO:0010154GO:GO:0016887GO:GO:0030983GO:GO:0032389
GO:GO:0048316Gramene:AT4G09140.1hmmpanther:PTHR10073hmmpanther:PTHR10073:SF40
HOGENOM:HOG000176000InParanoid:Q9ZRV4IntAct:Q9ZRV4InterPro:IPR002099
InterPro:IPR003594InterPro:IPR013507InterPro:IPR014721InterPro:IPR014762
InterPro:IPR020568InterPro:IPR032189iPTMnet:Q9ZRV4KEGG:ath:AT4G09140
KO:K08734ncoils:CoilOMA:KYAVHNPPaxDb:Q9ZRV4
Pfam:PF01119Pfam:PF13589Pfam:PF16413Pfam:Q9ZRV4
PhylomeDB:Q9ZRV4PIR:F85092PIR:T51620PRIDE:Q9ZRV4
PRO:PR:Q9ZRV4PROSITE:PS00058ProteinModelPortal:Q9ZRV4Proteomes:UP000006548
Reactome:R-ATH-5358565RefSeq:NP_567345.2scanprosite:PS00058SMART:SM01340
SMR:Q9ZRV4STRING:3702.AT4G09140.1SUPFAM:SSF54211SUPFAM:SSF55874
TAIR:AT4G09140tair10-symbols:ATMLH1tair10-symbols:MLH1TIGRfam:TIGR00585
TIGRFAMs:TIGR00585UniGene:At.671UniProt:Q9ZRV4
Coordinates (TAIR10) chr4:-:5817107..5821035
Molecular Weight (calculated) 82369.30 Da
IEP (calculated) 5.31
GRAVY (calculated) -0.30
Length 737 amino acids
Sequence (TAIR10)
(BLAST)
001: MIDDSSLTAE MEEEESPATT IVPREPPKIQ RLEESVVNRI AAGEVIQRPV SAVKELVENS LDADSSSISV VVKDGGLKLI QVSDDGHGIR REDLPILCER
101: HTTSKLTKFE DLFSLSSMGF RGEALASMTY VAHVTVTTIT KGQIHGYRVS YRDGVMEHEP KACAAVKGTQ IMVENLFYNM IARRKTLQNS ADDYGKIVDL
201: LSRMAIHYNN VSFSCRKHGA VKADVHSVVS PSRLDSIRSV YGVSVAKNLM KVEVSSCDSS GCTFDMEGFI SNSNYVAKKT ILVLFINDRL VECSALKRAI
301: EIVYAATLPK ASKPFVYMSI NLPREHVDIN IHPTKKEVSL LNQEIIIEMI QSEVEVKLRN ANDTRTFQEQ KVEYIQSTLT SQKSDSPVSQ KPSGQKTQKV
401: PVNKMVRTDS SDPAGRLHAF LQPKPQSLPD KVSSLSVVRS SVRQRRNPKE TADLSSVQEL IAGVDSCCHP GMLETVRNCT YVGMADDVFA LVQYNTHLYL
501: ANVVNLSKEL MYQQTLRRFA HFNAIQLSDP APLSELILLA LKEEDLDPGN DTKDDLKERI AEMNTELLKE KAEMLEEYFS VHIDSSANLS RLPVILDQYT
601: PDMDRVPEFL LCLGNDVEWE DEKSCFQGVS AAIGNFYAMH PPLLPNPSGD GIQFYSKRGE SSQEKSDLEG NVDMEDNLDQ DLLSDAENAW AQREWSIQHV
701: LFPSMRLFLK PPASMASNGT FVKVASLEKL YKIFERC
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)