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AT2G29890.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 0.835
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : villin-like 1
Curator
Summary (TAIR10)
Encodes a ubiquitously expressed villin-like protein, whose mRNA may be alternatively processed. Villin belongs to a superfamily of actin binding proteins called the villin/gelsolin family. Animal villins are involved in actin binding. VLN1 protein co-localizes with actin filaments in several assays. VLN1 binds and bundles F-actin in a calcium-independent manner. It does not nucleate, cap or sever actin filaments and it stabilizes actin filaments, protecting them from ADF-mediated depolymerization.
Computational
Description (TAIR10)
villin-like 1 (VLN1); CONTAINS InterPro DOMAIN/s: Gelsolin (InterPro:IPR007122), Villin headpiece (InterPro:IPR003128), Gelsolin domain (InterPro:IPR007123); BEST Arabidopsis thaliana protein match is: villin 4 (TAIR:AT4G30160.1); Has 3095 Blast hits to 1746 proteins in 186 species: Archae - 0; Bacteria - 6; Metazoa - 2441; Fungi - 102; Plants - 219; Viruses - 0; Other Eukaryotes - 327 (source: NCBI BLink).
Protein Annotations
BioGrid:2889eggNOG:ENOG410XR0AeggNOG:KOG0443EMBL:AC007113
EMBL:AF081201EMBL:CP002685EnsemblPlants:AT2G29890EnsemblPlants:AT2G29890.1
entrez:817539ExpressionAtlas:O81643Gene3D:1.10.950.10Gene3D:3.40.20.10
GeneID:817539Genevisible:O81643GO:GO:0005737GO:GO:0005856
GO:GO:0051017GO:GO:0051693hmmpanther:PTHR11977hmmpanther:PTHR11977:SF25
HOGENOM:HOG000233631InParanoid:O81643InterPro:IPR003128InterPro:IPR007122
InterPro:IPR007123InterPro:IPR029006InterPro:IPR030010iPTMnet:O81643
PANTHER:PTHR11977PANTHER:PTHR11977:SF25PaxDb:O81643Pfam:O81643
Pfam:PF00626Pfam:PF02209Pfscan:PS51089PhylomeDB:O81643
PIR:H84701PIR:T50671PRIDE:O81643PRINTS:PR00597
PRO:PR:O81643PROSITE:PS51089ProteinModelPortal:O81643Proteomes:UP000006548
RefSeq:NP_029567.1SMART:SM00153SMART:SM00262SMR:O81643
STRING:3702.AT2G29890.3SUPFAM:SSF47050SUPFAM:SSF55753TAIR:AT2G29890
tair10-symbols:ATVLN1tair10-symbols:VLN1UniGene:At.11948UniProt:O81643
Coordinates (TAIR10) chr2:+:12744597..12749474
Molecular Weight (calculated) 102955.00 Da
IEP (calculated) 5.35
GRAVY (calculated) -0.49
Length 909 amino acids
Sequence (TAIR10)
(BLAST)
001: MSRLSKDIDS AFQGVGTKSG LEIWCVYNKQ LISIPKSSFG KFHSGNAYLV LRTFLRKIES PQYDIHYWLG IDANEVDSIL ASDKALDLDA ALGCCTVQYR
101: EVQGQETEKF LSYFKPCIIP VEGKYSPKTG IAGETYQVTL LRCKGDHVVR VKEVPFLRSS LNHDDVFILD TASKVFLFAG CNSSTQEKAK AMEVVEYIKD
201: NKHDGRCEVA TIEDGKFSGD SDAGEFWSFF GGYAPIPKLS SSTTQEQTQT PCAELFWIDT KGNLHPTGTS SLDKDMLEKN KCYMLDCHSE VFVWMGRNTS
301: LTERKTSISS SEEFLRKEGR STTTSLVLLT EGLENARFRS FFNKWPQTVE SSLYNEGREK VAALFKQKGY DVEELPDEED DPLYTNCRDN LKVWRVDGDD
401: VSLLSIPDQT KLFTGDCYLV QYKYTYKERT EHLLYVWIGC ESIQQDRADA ITNASAIVGT TKGESVLCHI YQGNEPSRFF PMFQSLVVFK GGLSRRYKVL
501: LAEKEKIGEE YNENKASLFR VVGTSPRNMQ AIQVNLVATS LNSSYSYILQ YGASAFTWIG KLSSDSDHEV LDRMLYFLDT SCQPIYIREG NETDTFWNLL
601: GGKSEYPKEK EMRKQIEEPH LFTCSCSSDV LKVKEIYNFV QDDLTTEDVF LLDCQSEVYV WIGSNSNIKS KEEALTLGLK FLEMDILEEG LTMRTPVYVV
701: TEGHEPPFFT RFFEWVPEKA NMHGNSFERK LASLKGKKTS TKRSSGSQYR SQSKDNASRD LQSRSVSSNG SERGVSPCSS EKLLSLSSAE DMTNSSNSTP
801: VVKKLFSESL LVDPNDGVAR QESSSKSDIS KQKPRVGINS DLSSLESLAY SYEQLRVDSQ KPVTDIDATR REAYLTEKEF EERFGMAKSE FYALPKWKQN
901: KLKISLHLF
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)