AT1G67730.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:endoplasmic reticulum 1.000 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : beta-ketoacyl reductase 1 | ||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes one of the two Arabidopsis homologues to YBR159w encoding a S. cerevisiae beta-ketoacyl reductase (KCR), which catalyzes the first reduction during VLCFA (very long chain fatty acids, >18 carbon) elongation: KCR1 (At1g67730), KCR2 (At1g24470). Complementation of the yeast ybr159Delta mutant demonstrated that the two KCR proteins are divergent and that only AtKCR1 can restore heterologous elongase activity similar to the native yeast KCR gene. | ||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
beta-ketoacyl reductase 1 (KCR1); FUNCTIONS IN: oxidoreductase activity, ketoreductase activity, acetoacetyl-CoA reductase activity; INVOLVED IN: very long-chain fatty acid biosynthetic process, embryo development, cuticle development; LOCATED IN: endoplasmic reticulum, membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Short-chain dehydrogenase/reductase, conserved site (InterPro:IPR020904), NAD(P)-binding domain (InterPro:IPR016040), Glucose/ribitol dehydrogenase (InterPro:IPR002347), Short-chain dehydrogenase/reductase SDR (InterPro:IPR002198); BEST Arabidopsis thaliana protein match is: beta-ketoacyl reductase 2 (TAIR:AT1G24470.1); Has 86831 Blast hits to 86679 proteins in 3373 species: Archae - 739; Bacteria - 59178; Metazoa - 5127; Fungi - 3946; Plants - 2216; Viruses - 0; Other Eukaryotes - 15625 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr1:+:25391676..25393365 | ||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 35763.90 Da | ||||||||||||||||||||||||||||||||
| IEP (calculated) | 9.92 | ||||||||||||||||||||||||||||||||
| GRAVY (calculated) | 0.02 | ||||||||||||||||||||||||||||||||
| Length | 318 amino acids | ||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MEICTYFKSQ PTWLLILFVL GSISIFKFIF TLLRSFYIYF LRPSKNLRRY GSWAIITGPT DGIGKAFAFQ LAQKGLNLIL VARNPDKLKD VSDSIRSKYS 101: QTQILTVVMD FSGDIDEGVK RIKESIEGLD VGILINNAGM SYPYAKYFHE VDEELINNLI KINVEGTTKV TQAVLPNMLK RKKGAIINMG SGAAALIPSY 201: PFYSVYAGAK TYVDQFTKCL HVEYKKSGID VQCQVPLYVA TKMTKIRRAS FLVASPEGYA KAALRFVGYE AQCTPYWPHA LMGAVVSALP ESVFESFNIK 301: RCLQIRKKGL QKDSMKKE |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)