AT5G10480.1
Subcellular Consensus
(Prediction and Experimental) min: :max .
SUBAcon:endoplasmic reticulum 0.878 What is SUBAcon? |
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Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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Description (TAIR10) | protein_coding : Protein-tyrosine phosphatase-like, PTPLA | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Curator Summary (TAIR10) |
Protein tyrosine phosphatase-like involved in cell division and differentiation. Interacts with CDKA;1 only in its phosphorylated form, preventing dephosphorylation. Overexpression slowed down cell division in suspension cell cultures at the G2-to-M transition and early mitosis and inhibited Arabidopsis seedling growth. Localized in the cytoplasm of dividing cells but moved into the nucleus upon cell differentiation. Based on complementation of yeast mutant PAS2 has acyl-CoA dehydratase activity. It interacts with CER10, a component of the microsomal fatty acid elongase complex, suggesting a role in synthesis of VLCFAs (very long chain fatty acids). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Computational Description (TAIR10) |
PASTICCINO 2 (PAS2); CONTAINS InterPro DOMAIN/s: Protein-tyrosine phosphatase-like, PTPLA (InterPro:IPR007482); BEST Arabidopsis thaliana protein match is: Protein-tyrosine phosphatase-like, PTPLA (TAIR:AT5G59770.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Protein Annotations |
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Coordinates (TAIR10) | chr5:-:3298047..3300048 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Weight (calculated) | 25328.20 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
IEP (calculated) | 9.84 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GRAVY (calculated) | 0.45 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Length | 221 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sequence (TAIR10) (BLAST) |
001: MAGFLSVVRR VYLTLYNWIV FAGWAQVLYL AITTLKETGY ENVYDAIEKP LQLAQTAAVL EILHGLVGLV RSPVSATLPQ IGSRLFLTWG ILYSFPEVRS 101: HFLVTSLVIS WSITEIIRYS FFGFKEALGF APSWHLWLRY SSFLLLYPTG ITSEVGLIYL ALPHIKTSEM YSVRMPNILN FSFDFFYATI LVLAIYVPGS 201: PHMYRYMLGQ RKRALSKSKR E |
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See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)