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AT5G64960.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:30961429 (2019): nucleus
  • PMID:30447334 (2019): plasma membrane
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:24134884 (2013): cytoskeleton microtubules
  • PMID:18433157 (2008): cytosol
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : cyclin dependent kinase group C2
Curator
Summary (TAIR10)
Encodes CDKC;2, part of a CDKC kinase complex that is targeted by Cauliflower mosaic virus (CaMV) for transcriptional activation of viral genes. Also regulates plant growth and development. Co-localizes with spliceosomal components in a manner dependent on the transcriptional status of the cells and on CDKC2-kinase activity. Expression of CDKC2 modifies the location of spliceosomal components.
Computational
Description (TAIR10)
cyclin dependent kinase group C2 (CDKC2); FUNCTIONS IN: kinase activity; INVOLVED IN: in 6 processes; LOCATED IN: cytosol, nuclear body, nucleus, microtubule, spliceosomal complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: cyclin-dependent kinase C;1 (TAIR:AT5G10270.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT5G64960-MONOMERBioCyc:ARA:GQT-2793-MONOMERBioGrid:21862BRENDA:2.7.11.22
EC:2.7.11.22EC:2.7.11.23eggNOG:ENOG410XPIReggNOG:KOG0600
EMBL:AB019236EMBL:AF360134EMBL:AY039990EMBL:AY062449
EMBL:BT002565EMBL:CP002688EnsemblPlants:AT5G64960EnsemblPlants:AT5G64960.1
entrez:836620ExpressionAtlas:Q8W4P1GeneID:836620Genevisible:Q8W4P1
GO:GO:0004693GO:GO:0005524GO:GO:0005634GO:GO:0005829
GO:GO:0006397GO:GO:0008353GO:GO:0009615GO:GO:0009908
GO:GO:0016301GO:GO:0016604GO:GO:0048366GO:GO:0048440
GO:GO:0050792hmmpanther:PTHR24056hmmpanther:PTHR24056:SF227HOGENOM:HOG000233024
InParanoid:Q8W4P1IntAct:Q8W4P1InterPro:IPR000719InterPro:IPR008271
InterPro:IPR011009InterPro:IPR017441iPTMnet:Q8W4P1OMA:HHENVIH
PaxDb:Q8W4P1Pfam:PF00069Pfam:Q8W4P1Pfscan:PS50011
PhylomeDB:Q8W4P1PRIDE:Q8W4P1PRO:PR:Q8W4P1PROSITE:PS00107
PROSITE:PS00108PROSITE:PS50011ProteinModelPortal:Q8W4P1Proteomes:UP000006548
Reactome:R-ATH-112382Reactome:R-ATH-674695RefSeq:NP_201301.1scanprosite:PS00107
scanprosite:PS00108SMART:SM00220SMR:Q8W4P1STRING:3702.AT5G64960.1
SUPFAM:SSF56112TAIR:AT5G64960tair10-symbols:CDKC2tair10-symbols:CDKC;2
UniGene:At.72847UniProt:Q8W4P1
Coordinates (TAIR10) chr5:+:25955497..25958427
Molecular Weight (calculated) 57131.90 Da
IEP (calculated) 9.43
GRAVY (calculated) -0.81
Length 513 amino acids
Sequence (TAIR10)
(BLAST)
001: MAAAAFGQLN LEEPPPIWGS RSVDCFEKLE QIGEGTYGQV YMAKEIKTGE IVALKKIRMD NEREGFPITA IREIKILKKL HHENVIHLKE IVTSPGRDRD
101: DQGKPDNNKY KGGIYMVFEY MDHDLTGLAD RPGLRFTVPQ IKCYMKQLLT GLHYCHVNQV LHRDIKGSNL LIDNEGNLKL ADFGLARSYS HDHTGNLTNR
201: VITLWYRPPE LLLGATKYGP AIDMWSVGCI FAELLNGKPI LPGKTENEQL NKIYELCGSP DESNWPGVSK MPWYNQMKSS RPLKRRVREI YRHFDRHALE
301: LLEKMLVLDP SQRICAKDAL DAEYFWTDPL PCDPKSLPTY ESSHEFQTKK KRQQMRHNEE AAKKQKLQHP QQQHSRLPPQ QHGVGQSHAA PLWPAGPNHP
401: MNNNAPPPQI PAGGHYYGGK PRGGAPVPNR YPPSGNQTGG YNNQSRGGYS SGAYPPQGRG APYGAGPRGP SGGYGVGPPN YSQGGGQYGG SGGSGRGQNP
501: MGGARNQQYG WQP
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)