AT5G63910.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:vacuole 1.000 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : farnesylcysteine lyase | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes a farnesylcysteine lyase (EC 1.8.3.5) involved in a salvage /detoxification pathway of farnesylcysteine (FC) residues that are liberated during the degradation of prenylated proteins. Because FC is a competitive inhibitor of prenylcysteine methyltransferases involved in the down-regulation of ABA signaling, fcly mutants with elevated FC levels are hypersensitive to ABA. The protein also appears to be glycosylated when translated in vitro in the presence of microsomal membranes and it likely requires FAD for enzymatic activity. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
farnesylcysteine lyase (FCLY); FUNCTIONS IN: prenylcysteine oxidase activity; INVOLVED IN: prenylated protein catabolic process, abscisic acid mediated signaling pathway, farnesyl diphosphate metabolic process; LOCATED IN: plasma membrane, vacuole; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Prenylcysteine lyase (InterPro:IPR010795), Prenylcysteine oxidase (InterPro:IPR017046); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr5:-:25572053..25574077 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 55301.20 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 6.20 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.01 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 500 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MKDFPIAISL LFALLSPVLL PCSGDSTGGV EDDSPATVCI VGSGIGGSSV AHFLRNYSVS TGLNQAKILM FERHEIVGGR MRTVTVAGDT FEAGGSILHP 101: KNYHVKDFVE RFNLTVRLPT PIEESSAIGI WDGKRFVVKT FGSGTKFPFL DTIVSWVNDL YLFLRYGLSL LRMSSFIENT VDNFLKYYES LESRPIFDNV 201: EGMLKWSGLY NLTKLTLQEK LSEAQLSPLL VNELVTVITR INYGQSVLIS GLAGAVSLAG SGGGLWSVEG GNWQMAAKLI NHSDVTLHLN EKIESISYLE 301: NHYELKSTKG NSYKCDVTVV ATPLDEVDIQ FSPTISIPKR ELQHTHTTFV RGLLNPGYFG MKSLSDVPAL VGTLEDPLIP FSCISILRKY SKTDMTYKIF 401: TRQPASDSLL DELFSRRTET VRIDWGAYPK YHAPEVFAPF ILDDHHLYYV NAFENAASTM ETSAVAGENI ARLIISRFMT KESLSSSDKR SCSSGLHSDS |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)