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AT5G18170.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
mitochondrion 1.000
ASURE: mitochondrion
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31911558 (2020): mitochondrion
  • PMID:31871212 (2020): mitochondrion
  • PMID:31818904 (2020): mitochondrion
  • PMID:31615849 (2019): plastid plastid thylakoid
  • PMID:31520498 (2020): mitochondrion
  • PMID:31186290 (2019): cytosol None
  • PMID:31023727 (2019): mitochondrion
  • PMID:30961429 (2019): nucleus
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:30447334 (2019): plasma membrane
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:27943495 (2017): mitochondrion
  • PMID:27122571 (2016): mitochondrion
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:24727099 (2014): mitochondrion
  • PMID:24124904 (2013): plastid
  • PMID:23903016 (2013): plant-type vacuole plant-type vacuole membrane
  • PMID:23750852 (2013): mitochondrion
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:22968828 (2012): mitochondrion
  • PMID:22540835 (2012): mitochondrion
  • PMID:21841088 (2011): mitochondrion
  • PMID:21472856 (2011): mitochondrion
  • PMID:21311031 (2011): mitochondrion
  • PMID:19688752 (2009): mitochondrion
  • PMID:18998720 (2009): extracellular region
  • PMID:18385124 (2008): mitochondrion
  • PMID:17137349 (2006): mitochondrion
  • PMID:15215502 (2004): plant-type vacuole
  • PMID:14671022 (2004): mitochondrion
  • PMID:11743115 (2001): mitochondrion
  • PMID:11743114 (2001): mitochondrion
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : glutamate dehydrogenase 1
Curator
Summary (TAIR10)
Encodes the 43 kDa alpha-subunit of the glutamate dehydrogenase with a putative mitochondrial transit polypeptide and NAD(H)- and alpha-ketoglutarate-binding domains. Mitochondrial localization confirmed by subcellular fractionation. Combines in several ratios with GDH2 protein (GDH-beta) to form seven isoenzymes. Catalyzes the cleavage of glycine residues. May be involved in ammonia assimilation under conditions of inorganic nitrogen excess. The enzyme is almost exclusively found in the mitochondria of stem and leaf companion cells.
Computational
Description (TAIR10)
glutamate dehydrogenase 1 (GDH1); FUNCTIONS IN: in 6 functions; INVOLVED IN: response to cadmium ion, response to salt stress, nitrogen compound metabolic process, response to absence of light; LOCATED IN: mitochondrion; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Glutamate/phenylalanine/leucine/valine dehydrogenase (InterPro:IPR006095), Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal (InterPro:IPR006096), NAD(P)-binding domain (InterPro:IPR016040), Glutamate dehydrogenase (InterPro:IPR014362), Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain (InterPro:IPR006097); BEST Arabidopsis thaliana protein match is: glutamate dehydrogenase 3 (TAIR:AT3G03910.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT5G18170-MONOMEREC:1.4.1.3eggNOG:COG0334eggNOG:KOG2250
EMBL:AB012246EMBL:CP002688EMBL:U37771EMBL:U53527
EnsemblPlants:AT5G18170EnsemblPlants:AT5G18170.1entrez:831935ExpressionAtlas:Q43314
Gene3D:3.40.50.720GeneID:831935Genevisible:Q43314GO:GO:0004353
GO:GO:0005507GO:GO:0005524GO:GO:0005739GO:GO:0006520
GO:GO:0006807GO:GO:0008270GO:GO:0009646GO:GO:0009651
GO:GO:0046686GO:GO:0050897Gramene:AT5G18170.1hmmpanther:PTHR11606
hmmpanther:PTHR11606:SF12HOGENOM:HOG000243801InParanoid:Q43314IntAct:Q43314
InterPro:IPR006095InterPro:IPR006096InterPro:IPR006097InterPro:IPR014362
InterPro:IPR016040KEGG:ath:AT5G18170KO:K00261OMA:INNGEMH
PaxDb:Q43314Pfam:PF00208Pfam:PF02812Pfam:Q43314
PhylomeDB:Q43314PIR:S71217PIRSF:PIRSF000185PRIDE:Q43314
PRINTS:PR00082PRO:PR:Q43314PROSITE:PS00074ProteinModelPortal:Q43314
Proteomes:UP000006548Reactome:R-ATH-70614RefSeq:NP_197318.1scanprosite:PS00074
SMART:SM00839SMR:Q43314STRING:3702.AT5G18170.1SUPFAM:SSF51735
SUPFAM:SSF53223TAIR:AT5G18170tair10-symbols:GDH1UniGene:At.23609
UniProt:Q1H5A3UniProt:Q43314
Coordinates (TAIR10) chr5:+:6006172..6008248
Molecular Weight (calculated) 44526.60 Da
IEP (calculated) 6.85
GRAVY (calculated) -0.17
Length 411 amino acids
Sequence (TAIR10)
(BLAST)
001: MNALAATNRN FKLAARLLGL DSKLEKSLLI PFREIKVECT IPKDDGTLAS FVGFRVQHDN ARGPMKGGIR YHPEVDPDEV NALAQLMTWK TAVAKIPYGG
101: AKGGIGCDPS KLSISELERL TRVFTQKIHD LIGIHTDVPA PDMGTGPQTM AWILDEYSKF HGYSPAVVTG KPIDLGGSLG RDAATGRGVM FGTEALLNEH
201: GKTISGQRFV IQGFGNVGSW AAKLISEKGG KIVAVSDITG AIKNKDGIDI PALLKHTKEH RGVKGFDGAD PIDPNSILVE DCDILVPAAL GGVINRENAN
301: EIKAKFIIEA ANHPTDPDAD EILSKKGVVI LPDIYANSGG VTVSYFEWVQ NIQGFMWEEE KVNDELKTYM TRSFKDLKEM CKTHSCDLRM GAFTLGVNRV
401: AQATILRGWG A
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)