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AT5G09860.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
nucleus 0.999
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:24134884 (2013): cytoskeleton microtubules
  • PMID:23396599 (2013): nucleus nuclear envelope nuclear inner membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : nuclear matrix protein-related
Curator
Summary (TAIR10)
Encodes a component of the putative Arabidopsis THO/TREX complex: THO1 or HPR1 (At5g09860), THO2 (At1g24706), THO3 or TEX1 (At5g56130), THO5 (At5g42920, At1g45233), THO6 (At2g19430), and THO7 (At5g16790, At3g02950). THO/TREX complexes in animals have been implicated in the transport of mRNA precursors. Mutants of THO3/TEX1, THO1, THO6 accumulate reduced amount of small interfering (si)RNA, suggesting a role of the putative Arabidopsis THO/TREX in siRNA biosynthesis.
Computational
Description (TAIR10)
THO1; CONTAINS InterPro DOMAIN/s: THO complex, subunit THOC1 (InterPro:IPR021861); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
Protein Annotations
BioGrid:16124eggNOG:ENOG410XQEXeggNOG:KOG2491EMBL:AB016893
EMBL:AF424566EMBL:AF428323EMBL:BT000829EMBL:CP002688
EnsemblPlants:AT5G09860EnsemblPlants:AT5G09860.1entrez:830846ExpressionAtlas:Q93VM9
GeneID:830846Genevisible:Q93VM9GO:GO:0000347GO:GO:0003723
GO:GO:0005634GO:GO:0006397GO:GO:0006406GO:GO:0008380
GO:GO:0010267GO:GO:0031047GO:GO:0050832hmmpanther:PTHR13265
hmmpanther:PTHR13265:SF0HOGENOM:HOG000029433InParanoid:Q93VM9InterPro:IPR021861
iPTMnet:Q93VM9ncoils:CoilOMA:KWQKFSSPaxDb:Q93VM9
Pfam:PF11957Pfam:Q93VM9PhylomeDB:Q93VM9PRIDE:Q93VM9
PRO:PR:Q93VM9ProteinModelPortal:Q93VM9Proteomes:UP000006548RefSeq:NP_568219.1
STRING:3702.AT5G09860.1TAIR:AT5G09860tair10-symbols:AtHPR1tair10-symbols:AtTHO1
tair10-symbols:HPR1tair10-symbols:THO1UniGene:At.27041UniProt:Q93VM9
Coordinates (TAIR10) chr5:+:3066815..3070733
Molecular Weight (calculated) 68337.70 Da
IEP (calculated) 4.79
GRAVY (calculated) -0.70
Length 599 amino acids
Sequence (TAIR10)
(BLAST)
001: MDAFRDAILQ RAPIETFALK TVQHFIQPQK QTKLAQDENQ MLENMLRTLL QELVAAAAQS GEQIMQYGQL IDDDDDDDDI HGQIPHLLDV VLYLCEKEHV
101: EGGMIFQLLE DLTEMSTMKN CKDVFGYIES KQDILGKQEL FARGKLVMLR TCNQLLRRLS KANDVVFCGR ILMFLAHFFP LSERSAVNIK GVFNTSNETK
201: YEKDPPKGIS VDFNFYKTFW SLQEYFCNPA SLTSASTKWQ KFSSSLAVVL NTFDAQPLSE EEGEANSLEE EAATFNIKYL TSSKLMGLEL KDSSFRRHIL
301: LQCLIMFDYL RAPGKNDKDL PSETMKEELK SCEDRVKKLL EITPPKGKEF LRAVEHILER EKNWVWWKRD GCPPFEKQPI DKKSPNAGQK KRRQRWRLGN
401: KELSQLWRWA DQNPNALTDS QRVRTPDIAD YWKPLAEDMD PSAGIEDEYH HKNNRVYCWK GLRFTARQDL EGFSRFTEMG IEGVVPVELL PPEVRSKYQA
501: KPNEKAKRAK KEETKGGSHE TEGNQIGVSN SEAEAEGGRG DAETMESDAI ADTPTPEEQQ RLGGSDTENG QEAGQIEDGE TEEAGLMDTD LDHPPMPVS
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)