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AT5G07660.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:22522809 (2012): cytosol cytosolic ribosomes
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : structural maintenance of chromosomes 6A
Curator
Summary (TAIR10)
Encodes SMC6A (STRUCTURAL MAINTENANCE OF CHROMOSOMES 6A), a component of the SMC5/6 complex. SMC5/6 complex promotes sister chromatid alignment and homologous recombination after DNA damage.
Computational
Description (TAIR10)
structural maintenance of chromosomes 6A (SMC6A); FUNCTIONS IN: two-component sensor activity, ATP binding; INVOLVED IN: sister chromatid cohesion, chromosome segregation, response to X-ray, double-strand break repair via homologous recombination; LOCATED IN: chromosome, nucleus, membrane; EXPRESSED IN: 11 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: SMCs flexible hinge (InterPro:IPR010935), RecF/RecN/SMC protein, N-terminal (InterPro:IPR003395), Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain (InterPro:IPR003661); BEST Arabidopsis thaliana protein match is: P-loop containing nucleoside triphosphate hydrolases superfamily protein (TAIR:AT5G61460.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
Protein Annotations
eggNOG:COG1196eggNOG:KOG0250EMBL:AB010070EMBL:CP002688
EMBL:FJ869873EnsemblPlants:AT5G07660EnsemblPlants:AT5G07660.1entrez:830659
Gene3D:3.40.50.300GeneID:830659Genevisible:Q9FLR5GO:GO:0000155
GO:GO:0000724GO:GO:0005524GO:GO:0005634GO:GO:0007062
GO:GO:0010165GO:GO:0030915Gramene:AT5G07660.1hmmpanther:PTHR19306
hmmpanther:PTHR19306:SF6HOGENOM:HOG000030109InParanoid:Q9FLR5InterPro:IPR003395
InterPro:IPR010935InterPro:IPR027132InterPro:IPR027417InterPro:IPR033268
iPTMnet:Q9FLR5KEGG:ath:AT5G07660ncoils:CoilOMA:CLIDEST
PANTHER:PTHR19306PANTHER:PTHR19306:SF6PaxDb:Q9FLR5Pfam:PF02463
Pfam:Q9FLR5PhylomeDB:Q9FLR5PRIDE:Q9FLR5PRO:PR:Q9FLR5
ProteinModelPortal:Q9FLR5Proteomes:UP000006548RefSeq:NP_196383.1SMR:Q9FLR5
STRING:3702.AT5G07660.1SUPFAM:0038317SUPFAM:SSF52540SUPFAM:SSF75553
TAIR:AT5G07660tair10-symbols:SMC6AUniGene:At.32690UniProt:Q9FLR5
Coordinates (TAIR10) chr5:+:2422839..2429912
Molecular Weight (calculated) 122201.00 Da
IEP (calculated) 7.53
GRAVY (calculated) -0.74
Length 1058 amino acids
Sequence (TAIR10)
(BLAST)
0001: MDEHGDHRQS NPFNDQQTSS GKILRIRLEN FMCHSNLEIE FGDWVNFITG QNGSGKSAIL TALCVAFGCR ARGTQRAATL KDFIKTGCSY ALVYVELKNQ
0101: GEDAFKPEIY GDTLIIERRI SDSTSLTVLK DHQGRKISSR KEELRELVEH YNIDVENPCV IMSQDKSREF LHSGNDKDKF KFFYKATLLQ QVDDILQSIG
0201: TKLNSANALL DEMEKTIKPI EKEINELLEK IKNMEHVEEI TQQVLHLKKK LAWSWVYDVD RQLKEQNEKI VKFKERVPTC QNKIDRKLGE VESLRVSLTE
0301: KKAQVACLID ESTAMKRELE CLRQSMKKAA REKIALEEEY HHKCSNIQKI KDRVRRLERQ IEDINEMTIR STQVEQSEIE GKLNQLTVEV EKAESLVSSL
0401: KEEENMVMEK ASAGGKEKEH IEEMIRDHEK KQRNMNAHIN DLKKHQTNKV TAFGGDKVIN LLRAIERHHR RFKMPPIGPI GAHVTLINGN RWASAVEQAL
0501: GNLLNAFIVT DHKDLVALRD CGKEAKYNNL KIIIYDFSRP RLDIPRHMIP QTEHPTILSV LHSENTTVLN VLVDVSCVER HVLAENYEVG KIIAFERRLS
0601: HLKDVFTIDG YRMFSRGPVQ TTLPPRPRRP TRLCASFDDQ IKDLEIEASR EQSEIQECRG QKREAEMNLE GLESTMRRLK KQRTQLEKDL TRKELEMQDL
0701: KNSVASETKA SPTSSVNELH LEIMKFQKEI EEKESLLEKL QDSLKEAELK ANELKASYEN LYESAKGEIE ALEKAEDELK EKEDELHSAE TEKNHYEDIM
0801: KDKVLPEIKQ AETIYKELEM KRQESNKKAS IICPESEIKA LGPWDGPTPL QLSAQINKIN HRLKRENENY SESIDDLRIM HGEKEQKIGK KRKTYKSCRE
0901: KLKVCKDAVD SRWNKLQRNK DLLKRELTWQ FNHHLGKKGI SGNIRVSYED KTLSIEVKMP QDATNSAVRD TRGLSGGERS FSTLCFTLAL QNMTEAPIRA
1001: MDEFDVFMDA VSRKISLDTL IDFALKQGSQ WMFITPHDIS MVKSHEKIKK QQMAAPRS
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)