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AT4G37640.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
endoplasmic reticulum 1.000
ASURE: endoplasmic reticulum
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:10198075 (1999): endoplasmic reticulum
  • PMID:32219438 (2020): cytosol
  • PMID:31520498 (2020): mitochondrion
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:22923678 (2012): endoplasmic reticulum
  • PMID:22550958 (2012): plastid
  • PMID:21988472 (2012): plant-type vacuole plant-type vacuole membrane
  • PMID:21433285 (2011): plasma membrane
  • PMID:17317660 (2007): plasma membrane
  • PMID:16618929 (2006): endoplasmic reticulum
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : calcium ATPase 2
Curator
Summary (TAIR10)
Encodes a calmodulin-regulated Ca(2+)-pump located in the endoplasmic reticulum. Belongs to plant 2B ATPase's with an N-terminal autoinhibitor.
Computational
Description (TAIR10)
calcium ATPase 2 (ACA2); FUNCTIONS IN: calcium-transporting ATPase activity, calmodulin binding, calcium ion transmembrane transporter activity; INVOLVED IN: transport; LOCATED IN: endoplasmic reticulum, plasma membrane, endoplasmic reticulum membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, P-type, ATPase-associated domain (InterPro:IPR008250), ATPase, P-type, calcium-transporting, PMCA-type (InterPro:IPR006408), ATPase, P-type, H+ transporting proton pump (InterPro:IPR000695), Haloacid dehalogenase-like hydrolase (InterPro:IPR005834), ATPase, P-type cation-transporter, N-terminal (InterPro:IPR004014), ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter (InterPro:IPR001757), ATPase, P-type cation-transporter, C-terminal (InterPro:IPR006068), ATPase, P-type phosphorylation site (InterPro:IPR018303); BEST Arabidopsis thaliana protein match is: Cation transporter/ E1-E2 ATPase family protein (TAIR:AT2G22950.1); Has 47430 Blast hits to 34684 proteins in 3201 species: Archae - 904; Bacteria - 32793; Metazoa - 4036; Fungi - 2849; Plants - 2078; Viruses - 3; Other Eukaryotes - 4767 (source: NCBI BLink).
Protein Annotations
EC:3.6.3.8eggNOG:ENOG410XNNCeggNOG:KOG0204EMBL:BT010592
EnsemblPlants:AT4G37640EnsemblPlants:AT4G37640.1entrez:829918ExpressionAtlas:Q53XI0
Gene3D:1.20.1110.10Gene3D:3.40.1110.10GeneID:829918GO:GO:0005388
GO:GO:0005524GO:GO:0016021GO:GO:0046872Gramene:AT4G37640.1
hmmpanther:PTHR24093hmmpanther:PTHR24093:SF262IntAct:Q53XI0InterPro:IPR001757
InterPro:IPR004014InterPro:IPR006068InterPro:IPR006408InterPro:IPR008250
InterPro:IPR018303InterPro:IPR023214InterPro:IPR023298InterPro:IPR023299
InterPro:IPR024750KEGG:ath:AT4G37640KO:K01537OMA:PETEREH
PaxDb:Q53XI0Pfam:O81108Pfam:PF00122Pfam:PF00689
Pfam:PF00690Pfam:PF12515Pfam:PF12710PhylomeDB:Q53XI0
PRIDE:Q53XI0PRINTS:PR00120PROSITE:PS00154ProteinModelPortal:Q53XI0
RefSeq:NP_195479.1scanprosite:PS00154SMART:SM00831SMR:Q53XI0
STRING:3702.AT4G37640.1SUPFAM:0049471SUPFAM:0049473SUPFAM:SSF56784
SUPFAM:SSF81660TAIR:AT4G37640tair10-symbols:ACA2TIGRfam:TIGR01494
TIGRfam:TIGR01517TIGRFAMs:TIGR01494TIGRFAMs:TIGR01517TMHMM:TMhelix
UniGene:At.24252UniProt:O81108UniProt:Q53XI0
Coordinates (TAIR10) chr4:-:17683225..17686808
Molecular Weight (calculated) 110446.00 Da
IEP (calculated) 5.37
GRAVY (calculated) 0.21
Length 1014 amino acids
Sequence (TAIR10)
(BLAST)
0001: MESYLNENFD VKAKHSSEEV LEKWRNLCGV VKNPKRRFRF TANLSKRYEA AAMRRTNQEK LRIAVLVSKA AFQFISGVSP SDYTVPEDVK AAGFEICADE
0101: LGSIVESHDV KKLKFHGGVD GLAGKLKASP TDGLSTEAAQ LSQRQELFGI NKFAESEMRG FWVFVWEALQ DMTLMILGVC AFVSLIVGIA TEGWPKGSHD
0201: GLGIAASILL VVFVTATSDY RQSLQFRDLD KEKKKITVQV TRNGFRQKLS IYDLLPGDIV HLAIGDQVPA DGLFLSGFSV VIDESSLTGE SEPVMVNAQN
0301: PFLMSGTKVQ DGSCKMMITT VGMRTQWGKL MATLTEGGDD ETPLQVKLNG VATIIGKIGL FFAVVTFAVL VQGMFMRKLS TGTHWVWSGD EALELLEYFA
0401: IAVTIVVVAV PEGLPLAVTL SLAFAMKKMM NDKALVRHLA ACETMGSATT ICSDKTGTLT TNHMTVVKSC ICMNVQDVAN KGSSLQSEIP ESAVKLLIQS
0501: IFNNTGGEVV VNKHGKTELL GTPTETAILE LGLSLGGKFQ EERKSYKVIK VEPFNSTKKR MGVVIELPEG GRMRAHTKGA SEIVLAACDK VVNSSGEVVP
0601: LDEESIKYLN VTINEFANEA LRTLCLAYMD IEGGFSPDDA IPASGFTCVG IVGIKDPVRP GVKESVELCR RAGITVRMVT GDNINTAKAI ARECGILTDD
0701: GIAIEGPVFR EKNQEELLEL IPKIQVMARS SPMDKHTLVK QLRTTFDEVV AVTGDGTNDA PALHEADIGL AMGIAGTEVA KESADVIILD DNFSTIVTVA
0801: KWGRSVYINI QKFVQFQLTV NVVALVVNFS SACLTGSAPL TAVQLLWVNM IMDTLGALAL ATEPPNDELM KRLPVGRRGN FITNAMWRNI LGQAVYQFIV
0901: IWILQAKGKA MFGLDGPDST LMLNTLIFNC FVFCQVFNEI SSREMEEIDV FKGILDNYVF VVVIGATVFF QIIIIEFLGT FASTTPLTIT QWIFSIFIGF
1001: LGMPIAAGLK TIPV
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)