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AT4G34710.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
plastid 0.993
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:25402197 (2015): plastid plastid thylakoid plastid thylakoid membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : arginine decarboxylase 2
Curator
Summary (TAIR10)
encodes a arginine decarboxylase (ADC), a rate-limiting enzyme that catalyzes the first step of polyamine (PA) biosynthesis via ADC pathway in Arabidopsis thaliana. Arabidopsis genome has two ADC paralogs, ADC1 and ADC2. ADC2 is stress-inducible (osmotic stress). Double mutant analysis showed that ADC genes are essential for the production of PA, and are required for normal seed development. Overexpression causes phenotypes similar to GA-deficient plants and these plants show reduced levels of GA due to lower expression levels of AtGA20ox1, AtGA3ox3 and AtGA3ox1.
Computational
Description (TAIR10)
arginine decarboxylase 2 (ADC2); CONTAINS InterPro DOMAIN/s: Orn/DAP/Arg decarboxylase 2, C-terminal (InterPro:IPR022643), Orn/DAP/Arg decarboxylase 2, conserved site (InterPro:IPR022657), Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site (InterPro:IPR022653), Ornithine/DAP/Arg decarboxylase (InterPro:IPR000183), Arginine decarboxylase (InterPro:IPR002985), Orn/DAP/Arg decarboxylase 2, N-terminal (InterPro:IPR022644); BEST Arabidopsis thaliana protein match is: arginine decarboxylase 1 (TAIR:AT2G16500.1); Has 7853 Blast hits to 7777 proteins in 2122 species: Archae - 112; Bacteria - 5255; Metazoa - 102; Fungi - 32; Plants - 645; Viruses - 2; Other Eukaryotes - 1705 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT4G34710-MONOMERBioCyc:ARA:GQT-1021-MONOMERBioGrid:14905EC:4.1.1.19
eggNOG:COG1166eggNOG:ENOG410IKSUEMBL:AF009647EMBL:AL023094
EMBL:AL161586EMBL:AY039581EMBL:AY093982EMBL:CP002687
EnsemblPlants:AT4G34710EnsemblPlants:AT4G34710.1EnsemblPlants:AT4G34710.2entrez:829623
Gene3D:3.20.20.10GeneID:829623Genevisible:O23141GO:GO:0006527
GO:GO:0006596GO:GO:0006970GO:GO:0006979GO:GO:0008295
GO:GO:0008792GO:GO:0009409GO:GO:0009446GO:GO:0009611
GO:GO:0009651GO:GO:0009737GO:GO:0009753GO:GO:0033388
GO:GO:0080167Gramene:AT4G34710.1Gramene:AT4G34710.2gramene_pathway:4.1.1.19
gramene_pathway:PWY-40gramene_pathway:PWY-43gramene_pathway:PWY-6305gramene_plant_reactome:1119447
gramene_plant_reactome:6876021hmmpanther:PTHR11482hmmpanther:PTHR11482:SF36HOGENOM:HOG000029191
InParanoid:O23141IntAct:O23141InterPro:IPR000183InterPro:IPR002985
InterPro:IPR022643InterPro:IPR022644InterPro:IPR022653InterPro:IPR022657
InterPro:IPR029066iPTMnet:O23141KEGG:00330+4.1.1.19KEGG:ath:AT4G34710
KO:K01583OMA:FYYCDEDPANTHER:PTHR11482:SF36PaxDb:O23141
Pfam:O23141Pfam:PF00278Pfam:PF02784PhylomeDB:O23141
PIR:T05291PIRSF:PIRSF001336PRIDE:O23141PRINTS:PR01179
PRINTS:PR01180PRO:PR:O23141PROSITE:PS00878PROSITE:PS00879
ProteinModelPortal:O23141Proteomes:UP000006548RefSeq:NP_195197.1RefSeq:NP_974684.1
scanprosite:PS00878scanprosite:PS00879SMR:O23141STRING:3702.AT4G34710.1
SUPFAM:SSF51419TAIR:AT4G34710tair10-symbols:ADC2tair10-symbols:ATADC2
tair10-symbols:SPE2TIGRfam:TIGR01273TIGRFAMs:TIGR01273UniGene:At.2313
UniGene:At.43941UniPathway:UPA00186UniProt:O23141
Coordinates (TAIR10) chr4:-:16560315..16562450
Molecular Weight (calculated) 77223.70 Da
IEP (calculated) 4.94
GRAVY (calculated) -0.08
Length 711 amino acids
Sequence (TAIR10)
(BLAST)
001: MPALACVDTS FVPPAYAFSD TAGDVFIPAS SPTSAAVVVD RWSPSLSSSL YRIDGWGAPY FIANSSGNIS VRPHGSETLP HQDIDLLKIV KKVTGPKSSG
101: GLGLQLPLIV RFPDVLKNRL ECLQSAFDYA IKSQGYDSHY QGVYPVKCNQ DRFVVEDIVK FGSSFRFGLE AGSKPEILLA MSCLCKGSPD AFLVCNGFKD
201: AEYISLALLG RKLALNTVIV LEQEEELDLV IELSQKMNVR PVIGLRAKLR TKHSGHFGST SGEKGKFGLT TTQIVRVVRK LRQSGMLDCL QLLHFHIGSQ
301: IPSTSLLSDG VAEAAQLYCE LVRLGAHMKV IDIGGGLGID YDGSKSGESD LSVAYSLEEY AEAVVASVRV VCDRSSVKHP VICSESGRAI VSHHSVLIFE
401: AVSADKPMVH QATPGDIQFL LEGNEEARAN YEDLYAAVMR GDHESCLLYV DQLKQRCVEG FKEGVLSIEQ LASVDGLCEW VLKAIGASDP VHTYNINLSV
501: FTSIPDLWGI DQLFPIVPIH KLDQRPGARG ILSDLTCDSD GKINKFIGGE SSLPLHELDK NGSGGRYFLG MFLGGAYEEA LGGVHNLFGG PSVVRVSQSD
601: GPHSFAVTRA VPGQSSADVL RAMQHEPELM FQTLKHRAEE MMHTKGGSEG ENEEEEEDDE FNNVAASLDR SFHNMPYLAT EQASPSNSLS AAISNLGFYY
701: CDEDVYDYIS A
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)