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AT3G53110.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
cytosol 0.500
nucleus 0.500
ASURE: cytosol,nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31818904 (2020): mitochondrion
  • PMID:31615849 (2019): plastid plastid thylakoid
  • PMID:31520498 (2020): mitochondrion
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:26781341 (2016): plasma membrane
  • PMID:25900983 (2015): Golgi
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:25900983 (2015): plant-type vacuole plant-type vacuole membrane
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:17317660 (2007): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : P-loop containing nucleoside triphosphate hydrolases superfamily protein
Curator
Summary (TAIR10)
Encodes a putative DEAD-Box RNA Helicase and has RNA-dependent ATPase activity. Mutant is Sensitive to chilling stress and heat stress. Germination of the mutant is inhibited by ABA. LOS4 may be involved in temperature sensing. Is enriched in the nuclear envelope and also located in the cytoplasm. LOS4 is involved in export of poly A RNA.
Computational
Description (TAIR10)
LOW EXPRESSION OF OSMOTICALLY RESPONSIVE GENES 4 (LOS4); FUNCTIONS IN: RNA helicase activity, RNA-dependent ATPase activity, ATP-dependent helicase activity; INVOLVED IN: poly(A)+ mRNA export from nucleus, response to cold, response to heat, response to abscisic acid stimulus; LOCATED IN: nuclear envelope, plasma membrane, cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: RNA helicase, DEAD-box type, Q motif (InterPro:IPR014014), DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: eukaryotic initiation factor 4A-III (TAIR:AT3G19760.1); Has 40925 Blast hits to 40635 proteins in 3033 species: Archae - 702; Bacteria - 21081; Metazoa - 5720; Fungi - 4311; Plants - 2419; Viruses - 28; Other Eukaryotes - 6664 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:GQT-1457-MONOMERBioGrid:9794EC:3.6.4.13eggNOG:ENOG410XRGX
eggNOG:KOG0332EMBL:AL132958EMBL:AY057548EMBL:BT002444
EMBL:BT008867EMBL:CP002686EnsemblPlants:AT3G53110EnsemblPlants:AT3G53110.1
entrez:824477Gene3D:3.40.50.300GeneID:824477Genevisible:Q93ZG7
GO:GO:0003723GO:GO:0003724GO:GO:0004004GO:GO:0005524
GO:GO:0005635GO:GO:0005737GO:GO:0005886GO:GO:0006413
GO:GO:0008186GO:GO:0009408GO:GO:0009409GO:GO:0009737
GO:GO:0010468GO:GO:0010501GO:GO:0016973Gramene:AT3G53110.1
hmmpanther:PTHR24031hmmpanther:PTHR24031:SF318HOGENOM:HOG000268797InParanoid:Q93ZG7
InterPro:IPR001650InterPro:IPR011545InterPro:IPR014001InterPro:IPR014014
InterPro:IPR027417iPTMnet:Q93ZG7KEGG:ath:AT3G53110KO:K18655
OMA:WLTVEMIPaxDb:Q93ZG7Pfam:PF00270Pfam:PF00271
Pfam:Q93ZG7Pfscan:PS51192Pfscan:PS51194Pfscan:PS51195
PhylomeDB:Q93ZG7PIR:T46157PRIDE:Q93ZG7PRO:PR:Q93ZG7
PROSITE:PS51192PROSITE:PS51194PROSITE:PS51195ProteinModelPortal:Q93ZG7
Proteomes:UP000006548RefSeq:NP_190879.1SMART:SM00487SMART:SM00490
SMR:Q93ZG7STRING:3702.AT3G53110.1SUPFAM:SSF52540TAIR:AT3G53110
tair10-symbols:LOS4UniGene:At.35224UniGene:At.675UniProt:Q93ZG7
Coordinates (TAIR10) chr3:+:19687968..19690423
Molecular Weight (calculated) 55387.00 Da
IEP (calculated) 4.92
GRAVY (calculated) -0.43
Length 496 amino acids
Sequence (TAIR10)
(BLAST)
001: MADTVEKVPT VVESSSSSTV EASNSAEKTE PTTEKKKWGD VEDDDDEEEA VSELNSLSIK EEEKPDSILE EPEDSNIKAV TSGDTPYTSA SRFEDLNLSP
101: ELMKGLYVEM KFEKPSKIQA ISLPMIMTPP HKHLIAQAHN GSGKTTCFVL GMLSRVDPTL REPQALCICP TRELANQNME VLQKMGKFTG ITAELAVPDS
201: TRGAPAATRG APVSAHVVIG TPGTLKKWMA FKRLGLNHLK ILVFDEADHM LATDGFRDDS LKIMKDIGRV NPNFQVLLFS ATFNETVKDF VARTVKDPNQ
301: LFVKREDLAL DSVKQYKVVC PKEQNKIEVI KDQIMELGDI GQTIIFVKTK ASAQKVHKAL AEMGYDVTSV HGNLTESDRD KIVKEFKECL TQVLIATDVI
401: ARGFDQQRVN LVVNYNLPTK YETGEPDYEV YLHRVGRAGR FGRKGAVFNL LLDDGWDKEV MEKIEKYFEA NVKEIKSWNS EEEYKSALKE AGLLDE
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)