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AT3G23890.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:25402197 (2015): plastid plastid thylakoid plastid thylakoid membrane
  • PMID:23903016 (2013): plant-type vacuole plant-type vacuole membrane
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:22550958 (2012): plastid
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : topoisomerase II
Curator
Summary (TAIR10)
Encodes a topoisomerase II that is highly expressed in young seedlings. The protein is localized in the nucleus and gene expression levels are increased in proliferative tissues.
Computational
Description (TAIR10)
topoisomerase II (TOPII); CONTAINS InterPro DOMAIN/s: DNA topoisomerase, type IIA, subunit A/C-terminal (InterPro:IPR002205), DNA topoisomerase, type IIA, conserved site (InterPro:IPR018522), DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta (InterPro:IPR013758), DNA topoisomerase, type IIA, subunit A, alpha-helical (InterPro:IPR013757), DNA topoisomerase, type IIA, subunit B, domain 2 (InterPro:IPR013506), ATPase-like, ATP-binding domain (InterPro:IPR003594), DNA topoisomerase, type IIA, subunit B/N-terminal, alpha-beta (InterPro:IPR013759), DNA topoisomerase, type IIA, subunit B/N-terminal (InterPro:IPR001241), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568), DNA topoisomerase II, eukaryotic-type (InterPro:IPR001154), DNA topoisomerase, type IIA, central (InterPro:IPR013760); BEST Arabidopsis thaliana protein match is: DNA GYRASE B2 (TAIR:AT5G04130.1); Has 46226 Blast hits to 43639 proteins in 5982 species: Archae - 169; Bacteria - 28615; Metazoa - 2871; Fungi - 1392; Plants - 616; Viruses - 201; Other Eukaryotes - 12362 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT3G23890-MONOMERBioCyc:ARA:GQT-2551-MONOMEREC:5.99.1.3eggNOG:COG0187
eggNOG:COG0188eggNOG:KOG0355EMBL:AP001297EMBL:CP002686
EMBL:L21015EMBL:M84654EMBL:U12284EMBL:U12285
EnsemblPlants:AT3G23890EnsemblPlants:AT3G23890.1entrez:821972ExpressionAtlas:P30182
Gene3D:1.10.268.10Gene3D:3.30.1360.40Gene3D:3.30.230.10Gene3D:3.30.565.10
Gene3D:3.40.50.670Gene3D:3.90.199.10GeneID:821972Genevisible:P30182
GO:GO:0000712GO:GO:0000819GO:GO:0003677GO:GO:0003916
GO:GO:0003918GO:GO:0005524GO:GO:0005634GO:GO:0006265
GO:GO:0044774GO:GO:0046872hmmpanther:PTHR10169hmmpanther:PTHR10169:SF38
HOGENOM:HOG000216693InParanoid:P30182InterPro:IPR001241InterPro:IPR002205
InterPro:IPR003594InterPro:IPR006171InterPro:IPR013506InterPro:IPR013757
InterPro:IPR013758InterPro:IPR013759InterPro:IPR013760InterPro:IPR014721
InterPro:IPR018522InterPro:IPR020568InterPro:IPR024946InterPro:IPR031660
iPTMnet:P30182ncoils:CoilOMA:TCSPDPRPaxDb:P30182
Pfam:P30182Pfam:PF00204Pfam:PF00521Pfam:PF01751
Pfam:PF02518Pfam:PF16898Pfscan:PS50880PhylomeDB:P30182
PIR:S53598PRIDE:P30182PRINTS:PR00418PRO:PR:P30182
PROSITE:PS00177PROSITE:PS50880ProteinModelPortal:P30182Proteomes:UP000006548
Reactome:R-ATH-4615885RefSeq:NP_189031.1scanprosite:PS00177SMART:SM00387
SMART:SM00433SMART:SM00434SMR:P30182STRING:3702.AT3G23890.1
SUPFAM:SSF54211SUPFAM:SSF55874SUPFAM:SSF56719TAIR:AT3G23890
tair10-symbols:ATTOPIItair10-symbols:TOPIIUniGene:At.22343UniProt:P30182
Coordinates (TAIR10) chr3:+:8624931..8631106
Molecular Weight (calculated) 164116.00 Da
IEP (calculated) 7.62
GRAVY (calculated) -0.52
Length 1473 amino acids
Sequence (TAIR10)
(BLAST)
0001: MATKLPLQNS NAANVAKAPA KSRAAAGGKT IEEMYQKKSQ LEHILLRPDT YIGSIEKHTQ TLWVYEKDEM VQRPVTYVPG LYKIFDEILV NAADNKQRDA
0101: KMDSVQVVID VEQNLISVCN SGAGVPVEIH QEEGIYVPEM IFGHLLTSSN YDDNVKKTTG GRNGYGAKLT NIFSTEFIIE TADGKRLKKY KQVFENNMGK
0201: KSEPVITKCN KSENWTKVTF KPDLKKFNMT ELEDDVVALM SKRVFDIAGC LGKSVKVELN GKQIPVKSFT DYVDLYLSAA NKSRTEDPLP RLTEKVNDRW
0301: EVCVSLSEGQ FQQVSFVNSI ATIKGGTHVD YVTSQITNHI VAAVNKKNKN ANVKAHNVKN HLWVFVNALI DNPAFDSQTK ETLTLRQSSF GSKCELSEDF
0401: LKKVGKSGVV ENLLSWADFK QNKDLKKSDG AKTGRVLVEK LDDAAEAGGK NSRLCTLILT EGDSAKSLAL AGRSVLGNNY CGVFPLRGKL LNVREASTTQ
0501: ITNNKEIENL KKILGLKQNM KYENVNSLRY GQMMIMTDQD HDGSHIKGLL INFIHSFWPS LLQVPSFLVE FITPIVKATR KGTKKVLSFY SMPEYEEWKE
0601: SLKGNATGWD IKYYKGLGTS TAEEGKEYFS NLGLHKKDFV WEDEQDGEAI ELAFSKKKIE ARKNWLSSYV PGNHLDQRQP KVTYSDFVNK ELILFSMADL
0701: QRSIPSMVDG LKPGQRKILF VAFKKIARKE MKVAQLVGYV SLLSAYHHGE QSLASAIIGM AQDYVGSNNI NLLLPNGQFG TRTSGGKDSA SARYIFTKLS
0801: PVTRILFPKD DDLLLDYLNE DGQRIEPTWY MPIIPTVLVN GAEGIGTGWS TFIPNYNPRE IVANVRRLLN GESMVPMDPW YRGFKGTIEK TASKEGGCTY
0901: TITGLYEEVD ETTIRITELP IRRWNDDYKN FLQSLKTDNG APFFQDVKAY NDEKSVDFDL ILSEENMLAA RQEGFLKKFK LTTTIATSNM HLFDKKGVIK
1001: KYVTPEQILE EFFDLRFEYY EKRKETVVKN MEIELLKLEN KARFILAVLS GEIIVNKRKK ADIVEDLRQK GFTPFPRKAE SVEAAIAGAV DDDAAEEPEE
1101: ILVDPESSSS YIPGSEYDYL LAMAIASLTI EKVEELLADR DKMIIAVADM KKTTPKSLWL SDLESLDKEL EKLDLKDAQV QQAIEAAQKK IRAKSGAAVK
1201: VKRQAPKKPA PKKTTKKASE SETTEASYSA MDTDNNVAEV VKPKARQGAK KKASESETTE ASHSAMDTDN NVAEVVKPKG RQGAKKKAPA AAKEVEEDEM
1301: LDLAQRLAQY NFGSAPADSS KTAETSKAIA VDDDDDDVVV EVAPVKKGGR KPAATKAAKP PAAPRKRGKQ TVASTEVLAI GVSPEKKVRK MRSSPFNKKS
1401: SSVMSRLADN KEEESSENVA GNSSSEKSGG DVSAISRPQR ANRRKMTYVL SDSESESAND SEFDDIEDDE DDE
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)