AT3G14270.1
Subcellular Consensus
(Prediction and Experimental) min: :max .
SUBAcon:vacuole 0.969 What is SUBAcon? |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Experimental Localisations and PPI |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
SUBAcon links
AGI-AGI relationships |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Description (TAIR10) | protein_coding : phosphatidylinositol-4-phosphate 5-kinase family protein | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Curator Summary (TAIR10) |
Encodes a protein that is predicted to act as a 1-phosphatidylinositol-3-phosphate (PtdIns3P) 5-kinase based on its homology to Fab1 from yeast. It contains an FYVE domain required for binding to PtdIns3P-containing membranes in yeast, as well as a Cpn60_TCP1 homology domain plus a kinase domain. fab1a/fab1b pollen grains not viable and have defective vacuolar organization. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Computational Description (TAIR10) |
FORMS APLOID AND BINUCLEATE CELLS 1B (FAB1B); CONTAINS InterPro DOMAIN/s: Chaperonin Cpn60/TCP-1 (InterPro:IPR002423), Zinc finger, FYVE-type (InterPro:IPR000306), Zinc finger, FYVE-related (InterPro:IPR017455), Zinc finger, FYVE/PHD-type (InterPro:IPR011011), Phosphatidylinositol-4-phosphate 5-kinase, core (InterPro:IPR002498); BEST Arabidopsis thaliana protein match is: 1-phosphatidylinositol-4-phosphate 5-kinases;zinc ion binding;1-phosphatidylinositol-3-phosphate 5-kinases (TAIR:AT4G33240.2); Has 8765 Blast hits to 8134 proteins in 458 species: Archae - 587; Bacteria - 13; Metazoa - 3836; Fungi - 1744; Plants - 978; Viruses - 3; Other Eukaryotes - 1604 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Protein Annotations |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Coordinates (TAIR10) | chr3:+:4754624..4761185 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Weight (calculated) | 200842.00 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
IEP (calculated) | 5.72 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GRAVY (calculated) | -0.51 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Length | 1791 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sequence (TAIR10) (BLAST) |
0001: MGTRDSNNRT FSEIVGLIKS WLPWRSEPAT VSRDFWMPDQ SCRVCYECDC QFTLINRRHH CRHCGRVFCG KCTANSIPFA PSDLRTPRED WERIRVCNYC 0101: FRQWEQGDGG PHVSNITELS TSPSETSLLS SKTSTTANSS SFALGSMPGL IGLNQRVHHG SDVSLHGVSS METSVTKQGK ETSRRSSFIA TDVEDPSRFA 0201: LNSIRSDDEY DEYGAYQTDI ETSHSPRANE YYGPMEYNGM GIDDVPCKHL GGETADQKSL SGSPLIHQCL ESLIREGSEQ FQKKSEHDGR DECEASSPAD 0301: ISDDQVVEPV DFENNGLLWV PPEPENEEDE RESALFDEED NEGDASGEWG YLRPSTSFGS GEYRGEDRTT EEHKKAMKNV VDGHFRALLA QLLQVENISV 0401: SDEEGKESWL EIITSLSWEA ANLLKPDMSK SGGMDPGGYV KVKCLASGFR HDSMVVKGVV CKKNVVNRRM STKIEKARLL ILGGGLEYQR VSNQLSSFDT 0501: LLQQEKDHLK MAVAKIHAER PNILLVEKSV SRFAQEYLLA KDISLVLNIK RPLLDRIARC TGAQIIPSVD HLSSQKLGYC ENFRVDRYPE EHGSTGQVGK 0601: KVVKTLMYFE HCPKPLGFTI LLRGANEDEL KKVKHVVQYG VFAAYHLALE TSFLADEGAS PELPLNSPIT VALPDKSTSI ERSISTVPGF TVSTYEKSPT 0701: MLSCAEPQRA NSVPVSELLS TTTNLSIQKD IPPIPYGSGW QAREINPSFV FSRHNISLNL PDRVIESRNS DLSGRSVPVD TPADKSNPIV VADETTNNSL 0801: HLSGQGFVRK SSQIGTSIMV ENQDNGSELT IAQQQNNEKP KETQSQKEEF PPSPSDHQSI LVSLSSRSVW KGTVCERSHL FRIKYYGSFD KPLGRFLRDH 0901: LFDQSYRCRS CEMPSEAHVH CYTHRQGSLT ISVKKLQDYL LPGEKEGKIW MWHRCLRCPR LNGFPPATLR VVMSDAAWGL SFGKFLELSF SNHAAASRVA 1001: CCGHSLHRDC LRFYGFGNMV ACFRYATIDV HSVYLPPSIL SFNYENQDWI QRETDEVIER AELLFSEVLN AISQIAEKGF RRRIGELEEV LQKEKAEFEE 1101: NMQKILHREV NEGQPLVDIL ELYRIHRQLL FQSYMWDHRL INASTLHKLE NSDDTKREEN EKPPLAKSQT LPEMNAGTNS LLTGSEVNLN PDGDSTGDTG 1201: SLNNVQKEAD TNSDLYQEKD DGGEVSPSKT LPDTSYPLEN KVDVRRTQSD GQIVMKNLSA TLDAAWIGER QTSVEIPTNN KVSLPPSTMS NSSTFPPISE 1301: GLMPIDLPEQ QNEFKVAYPV SPALPSKNYE NSEDSVSWLS VPFLNFYRSI NKNFLLSSQK LDTFGEHSPI YISSFREAEL QGGPRLLLPV GLNDIVVPVY 1401: DDEPTSMIAY ALMSPEYQRQ TSAEGESLVS YPSELNIPRP VDDTIFDPSR SNGSVDESIL SISSSRSTSL LDPLSYTKAL HARVSYGEDG TLGKVKYTVT 1501: CYYAKRFEAL RGICLPSELE YIRSLSRCKK WGAQGGKSNV FFAKTLDDRF IIKQVTKTEL ESFIKFAPAY FKYLSESIST KSPTCLAKIL GIYQVATKQL 1601: KSGKETKMDV LIMENLLFGR TVKRLYDLKG SSRARYNPDS SGSNKVLLDQ NLIEAMPTSP IFVGNKAKRL LERAVWNDTA FLALGDVMDY SLLVGVDEEK 1701: NELVLGIIDF LRQYTWDKHL ESWVKFTGIL GGPKNEAPTV ISPKQYKRRF RKAMTTYFLM VPDQWSPPNV VANNSKSDQP EETSQAGTQA E |
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
See Also |
|
Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)