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AT3G08950.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
mitochondrion 1.000
ASURE: mitochondrion
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
FP Images

Arabidopsis cell culture (mitochondrial marker)

At3g08950-GFP
(full-length)
mitochondrial marker-RFPoverlay

Images by Sandra Tanz

Arabidopsis cell culture (plastidal marker)

At3g08950-GFP
(full-length)
plastidal marker-RFPoverlay

Images by Sandra Tanz
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : electron transport SCO1/SenC family protein
Curator
Summary (TAIR10)
Encodes HCC1, homologue of the copper chaperone SCO1 (synthesis of cytochrome c oxidase 1) from the yeast Saccharomyces cerevisiae. SCO1 encodes a mitochondrial protein that is essential for the correct assembly of complex IV in the respiratory chain. HCC1 is localized in the mitochondrion. A chimeric yeast Sco1-Arabidopsis HCC1 protein complements yeast Sco1 activity. Embryos of hcc1 mutants became arrested at various developmental stages, mostly at the heart stage.
Computational
Description (TAIR10)
electron transport SCO1/SenC family protein; FUNCTIONS IN: copper ion binding; INVOLVED IN: copper ion transport, respiratory chain complex IV assembly, cellular copper ion homeostasis, cell redox homeostasis; LOCATED IN: mitochondrion, mitochondrial inner membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Synthesis of cytochrome c oxidase, Sco1/Sco2 (InterPro:IPR017276), Copper chaperone SCO1/SenC (InterPro:IPR003782), Thioredoxin fold (InterPro:IPR012335), Thioredoxin-like (InterPro:IPR017936), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: Thioredoxin superfamily protein (TAIR:AT4G39740.1); Has 4072 Blast hits to 4072 proteins in 1098 species: Archae - 11; Bacteria - 2439; Metazoa - 165; Fungi - 147; Plants - 84; Viruses - 0; Other Eukaryotes - 1226 (source: NCBI BLink).
Protein Annotations
BioGrid:5380eggNOG:COG1999eggNOG:KOG2792EMBL:AC010871
EMBL:AY070393EMBL:AY085259EMBL:AY096736EMBL:CP002686
EnsemblPlants:AT3G08950EnsemblPlants:AT3G08950.1entrez:820046Gene3D:3.40.30.10
GeneID:820046Genevisible:Q8VYP0GO:GO:0005507GO:GO:0005739
GO:GO:0005743GO:GO:0009793GO:GO:0016021GO:GO:0033617
Gramene:AT3G08950.1hmmpanther:PTHR12151hmmpanther:PTHR12151:SF5HOGENOM:HOG000258140
InParanoid:Q8VYP0IntAct:Q8VYP0InterPro:IPR003782InterPro:IPR012336
iPTMnet:Q8VYP0KEGG:ath:AT3G08950KO:K07152OMA:ISRNQYI
PANTHER:PTHR12151PaxDb:Q8VYP0Pfam:PF02630Pfam:Q8VYP0
Pfscan:PS51352PhylomeDB:Q8VYP0PRIDE:Q8VYP0PRO:PR:Q8VYP0
PROSITE:PS51352ProteinModelPortal:Q8VYP0Proteomes:UP000006548RefSeq:NP_566339.1
SMR:Q8VYP0STRING:3702.AT3G08950.1SUPFAM:SSF52833TAIR:AT3G08950
tair10-symbols:HCC1TMHMM:TMhelixUniGene:At.28371UniProt:Q8VYP0
Coordinates (TAIR10) chr3:+:2727285..2729289
Molecular Weight (calculated) 37197.10 Da
IEP (calculated) 7.55
GRAVY (calculated) -0.45
Length 334 amino acids
Sequence (TAIR10)
(BLAST)
001: MASALCRTAS RLRSVQLFRR IRVSSDLLSA SSPSPACISD ALRHGDFSLP RSFFSLNCGI EMLKMDQRCL LSTSASDTTS KHDSGKPETK SSEKNEKSGG
101: SESSDGGSDH KNERASGKDV RGGPVSWMSF FLLFATGAGL VYYYDTQKKR HIEDINKNSI AVKEGPSAGK AAIGGPFSLI RDDGKRVTEK NLMGKWTILY
201: FGFTHCPDIC PDELIKLAAA IDKIKENSGV DVVPVFISVD PERDTVQQVH EYVKEFHPKL IGLTGSPEEI KSVARSYRVY YMKTEEEDSD YLVDHSIVMY
301: LMSPEMNFVK FYGKNHDVDS LTDGVVKEIR QYRK
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)