AT2G46240.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:nucleus 0.741 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : BCL-2-associated athanogene 6 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
A member of Arabidopsis BAG (Bcl-2-associated athanogene) proteins, plant homologs of mammalian regulators of apoptosis. Expression of BAG6 in leaves was strongly induced by heat stress. Knockout mutants exhibited enhanced susceptibility to fungal pathogen Botrytis cinerea. Plant BAG proteins are multi-functional and remarkably similar to their animal counterparts, as they regulate apoptotic-like processes ranging from pathogen attack, to abiotic stress, to plant development. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
BCL-2-associated athanogene 6 (BAG6); CONTAINS InterPro DOMAIN/s: Apoptosis regulator, Bcl-2 protein, BAG (InterPro:IPR003103), IQ calmodulin-binding region (InterPro:IPR000048); BEST Arabidopsis thaliana protein match is: BCL-2-associated athanogene 5 (TAIR:AT1G12060.1); Has 21821 Blast hits to 15371 proteins in 1199 species: Archae - 184; Bacteria - 2603; Metazoa - 10110; Fungi - 2300; Plants - 994; Viruses - 95; Other Eukaryotes - 5535 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr2:+:18986586..18989827 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 116765.00 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 4.94 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.93 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 1043 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
0001: MMPVYMDPSQ PCQMRPQEYY YQGFGNNSQH MAMDAPPPCH GSCVHGNFPA YWPPCYPPQV PYHQCCMNRS AFHPPHASYA PSCYVHPPFP VGYQPWFDVE 0101: KDVPGKHHCG KCSSQMCDLK KDRGVVIEEH EPEIEKGEAV LPVRSTNCPY PIIWIPHENA RNQEYRSSLG LGKHNQPPAE VRAPDNMTIQ KSFPESWRGC 0201: FPFDESSMKS LVQNQDSKKA QNGKTVEAPF DISKFKSLLQ GQDMKEAQIQ KNKEELGQLT YPTSWVPSRR KRDDVEASES SNEDRKKMQN GKTVEYPFDI 0301: SMIKSLIQGQ DVKEAQNQKN KEEPGQVPYP IFWIPSYGKR KDVEASESKE SSNEGRNLES CPSDLHRNEG QITQAKGKEG NFECNVLSDA EEKSSVINIP 0401: VANHLQEPRN IPVKLSENHL PKPTEPTKRI AKNEPVKSTK KEQSSSSSEA SKLPPVCLRV DPLPKERNGG SKSVSHPKRM EKSKETKIAA PLSSKKAESR 0501: TVPEACNVKC EDANAEMKMA EGSLNALRTE KGSVESNSNL QEESNGEIIK PCEAKENREQ PAKKSFTEEE AARIIQSMYR GYDVRRWEPI KKLKEIATVR 0601: EQMGDVKKRI EALEASTDQH IEEKEIVVNG ELVMNLLLKL DAVEGLHPSI REFRKALATE LSSIQDKLDS LKNSCASAEK EAVKEQVEIK SQPSDSPVNL 0701: EHSQLTEENK MVSDTNLEKV LRLSPEEHPM SVLNRTDEKQ AESAAETEEG YGLFETLATD SKQATENAAA ASSTTIPEKI GEVETVVPGN PPSADGNGMT 0801: VTNVEENKAM VVESLEEPIN ELPQMVEETE TNSIRDPENA SEVSEAETNS SENENRKGED DIVLHSEKNV ELSELPVGVI DEETQPLSQD PSSSYTREGN 0901: MTAMDPKTAS QEETEVDHSP NNSKGIGQQT SEPQDEKEQS PETEVIVKEQ PLETEVILNE QAPEPEITEP GISKETKKLM EENQRFKETM ETLVKAGREQ 1001: LEVISKLTSR VKSLEKKLSH KKKTQIRRRA SKPMSVSPTD AVL |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)