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AT2G44270.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
mitochondrion 0.588
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : repressor of lrx1
Curator
Summary (TAIR10)
Encodes ROL5, a repressor of lrx1 mutants that develop aberrant root hairs. ROL5 is a homolog of yeast Ncs6p that affects TOR signaling. The target of rapamycin (TOR) pathway is a major regulator of cell growth in eukaryotes, and inhibition of this pathway by rapamycin reduces cell growth. ROL5 might function as a mitochondrial component of the TOR pathway that influences the plant's response to ROS (reactive oxygen species).
Computational
Description (TAIR10)
repressor of lrx1 (ROL5); FUNCTIONS IN: ATP binding; INVOLVED IN: response to reactive oxygen species, regulation of plant-type cell wall organization or biogenesis; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Uncharacterised protein family UPF0021, C-terminal (InterPro:IPR000541), PP-loop (InterPro:IPR011063), 2-thiocytidine tRNA biosynthesis protein, TtcA (InterPro:IPR012089); BEST Arabidopsis thaliana protein match is: 2-thiocytidine tRNA biosynthesis protein, TtcA (TAIR:AT1G76170.1); Has 5057 Blast hits to 4981 proteins in 1812 species: Archae - 336; Bacteria - 3752; Metazoa - 169; Fungi - 215; Plants - 64; Viruses - 0; Other Eukaryotes - 521 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:GQT-2058-MONOMERBioCyc:ARA:GQT-386-MONOMERBioGrid:4371EC:2.7.7.-
EMBL:AC004521EMBL:AK117259EMBL:BT008353EMBL:CP002685
EnsemblPlants:AT2G44270EnsemblPlants:AT2G44270.1entrez:819035ExpressionAtlas:O64862
Gene3D:3.40.50.620GeneID:819035Genevisible:O64862GO:GO:0000049
GO:GO:0002098GO:GO:0005737GO:GO:0016779GO:GO:0032447
GO:GO:0034227HAMAP:MF_03053hmmpanther:PTHR11807hmmpanther:PTHR11807:SF12
HOGENOM:HOG000225864InParanoid:O64862IntAct:O64862InterPro:IPR000541
InterPro:IPR011063InterPro:IPR012089InterPro:IPR014729InterPro:IPR032442
iPTMnet:O64862Pfam:O64862Pfam:PF01171Pfam:PF16503
PhylomeDB:O64862PIR:T02383PIRSF:PIRSF004976PRIDE:O64862
PRO:PR:O64862ProteinModelPortal:O64862Proteomes:UP000006548RefSeq:NP_181956.2
SMR:O64862SUPFAM:SSF52402TAIR:AT2G44270tair10-symbols:ROL5
TIGRfam:TIGR00269TIGRFAMs:TIGR00269UniGene:At.36779UniPathway:UPA00988
UniProt:O64862
Coordinates (TAIR10) chr2:-:18298078..18300153
Molecular Weight (calculated) 40280.90 Da
IEP (calculated) 9.03
GRAVY (calculated) -0.35
Length 355 amino acids
Sequence (TAIR10)
(BLAST)
001: MEAKNKKAVA SRLCCLCNLR RPVLKRPKTL QQICRECFYE VFEEEIHQVI VQNRLFKSGE RVAIGASGGK DSTVLAYVLS ELNRRHNYGL DLFLLSIDEG
101: ITGYRDDSLE TVKRNEVQYG LPLKIVSYKD LYGWTMDEIV KMIGLKNNCT FCGVFRRQAL DRGAALLKVE KLVTGHNADD IAETVLLNIL RGDIARLSRC
201: TSITTGEDGP IPRCKPFKYT YEKEIVMYAY FKKLDYFSTE CIYSPNAYRG FAREFIKDLE RIRPRAILDI IKSGEDFRIA TTTKMPEQGT CERCGYISSQ
301: KWCKACVLLE GLNRGLPKMG IGRPRGVNGD HNKETKKPGS VAKSIESKQC GSLDF
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)