AT5G59440.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:cytosol 0.333 mitochondrion 0.333 nucleus 0.333 ASURE: cytosol,mitochondrion,nucleus What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : P-loop containing nucleoside triphosphate hydrolases superfamily protein | ||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes thymidylate kinase which exists in two isoforms in plants. The longer variant of 263 amino acids with a N-terminal extension that is required for localization to the mitochondrion. The second isoform of 224 residues is localized to the cytoplasm and nucleoplasm. Peak of expression occurs during G1/S phase transition. | ||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
ZEUS1 (ZEU1); FUNCTIONS IN: thymidylate kinase activity, ATP binding; INVOLVED IN: dTDP biosynthetic process, pyrimidine deoxyribonucleoside interconversion, anaerobic respiration; LOCATED IN: nucleoplasm, mitochondrion, cytoplasm; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Thymidylate kinase (InterPro:IPR018094), Thymidylate kinase-like (InterPro:IPR000062), Thymidylate kinase, conserved site (InterPro:IPR018095); Has 5519 Blast hits to 5517 proteins in 2216 species: Archae - 247; Bacteria - 3946; Metazoa - 202; Fungi - 154; Plants - 114; Viruses - 143; Other Eukaryotes - 713 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr5:+:23971533..23972729 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 29551.20 Da | ||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 8.45 | ||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.37 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 263 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MKRICSVSSV QLFSRSFRAL ASPRSLNYPL QCIKRSSVRM ESSNFSSGVR TESSVKPRGA LIVLEGLDRS GKSTQCAKLL SFLNGLGHPT ELWRFPDRET 101: SVGQMISAYL SNKSQLDDHT IHLLFSANRW EKRSLMEEKL KTGTTLIVDR YSYSGVAFSS AKGLDIEWCK APEIGLLAPD SVLYLDISPE RAAERGGYGD 201: ERYERVEFQK KVADFYQTLG DSSWKIINAS DAMEEVEKKI QQVVLDQVKE CTEGKPLSLL WSS |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)