suba logo
AT2G25140.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

.
SUBAcon:
mitochondrion 1.000
ASURE: mitochondrion
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : casein lytic proteinase B4
Curator
Summary (TAIR10)
Encodes ClpB4, which belongs to the Casein lytic proteinase/heat shock protein 100 (Clp/Hsp100) family. Targeted to the mitochondrion, also referred to as ClpB-m. Transcripts of ClpB4 accumulate dramatically at high temperatures, suggesting that it may be involved in response to heat stress.
Computational
Description (TAIR10)
casein lytic proteinase B4 (CLPB4); FUNCTIONS IN: nucleoside-triphosphatase activity, ATPase activity, nucleotide binding, ATP binding; INVOLVED IN: response to heat; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Clp ATPase, C-terminal (InterPro:IPR019489), ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-2 (InterPro:IPR013093), ATPase, AAA-type, core (InterPro:IPR003959), Chaperonin clpA/B (InterPro:IPR001270), Chaperonin ClpB (InterPro:IPR017730), Chaperonin ClpA/B, conserved site (InterPro:IPR018368), Clp, N-terminal (InterPro:IPR004176); BEST Arabidopsis thaliana protein match is: casein lytic proteinase B3 (TAIR:AT5G15450.1); Has 30488 Blast hits to 27328 proteins in 3166 species: Archae - 421; Bacteria - 19864; Metazoa - 870; Fungi - 613; Plants - 740; Viruses - 7; Other Eukaryotes - 7973 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT2G25140-MONOMERBioGrid:2404eggNOG:COG0542eggNOG:KOG1051
EMBL:AY070722EMBL:BT002223EMBL:CP002685EnsemblPlants:AT2G25140
EnsemblPlants:AT2G25140.1entrez:817052Gene3D:1.10.1780.10Gene3D:3.40.50.300
GeneID:817052Genevisible:Q8VYJ7GO:GO:0005524GO:GO:0005739
GO:GO:0009408GO:GO:0009507GO:GO:0009570GO:GO:0009941
GO:GO:0016485Gramene:AT2G25140.1hmmpanther:PTHR11638hmmpanther:PTHR11638:SF86
HOGENOM:HOG000218211InParanoid:Q8VYJ7IntAct:Q8VYJ7InterPro:IPR001270
InterPro:IPR003593InterPro:IPR003959InterPro:IPR004176InterPro:IPR017730
InterPro:IPR018368InterPro:IPR019489InterPro:IPR027417InterPro:IPR028299
iPTMnet:Q8VYJ7KEGG:ath:AT2G25140KO:K03695ncoils:Coil
OMA:SHHILETPaxDb:Q8VYJ7Pfam:PF00004Pfam:PF02861
Pfam:PF07724Pfam:PF10431Pfam:Q8VYJ7PhylomeDB:Q8VYJ7
PIR:G84644PRIDE:Q8VYJ7PRINTS:PR00300PRO:PR:Q8VYJ7
PROSITE:PS00870PROSITE:PS00871ProteinModelPortal:Q8VYJ7Proteomes:UP000006548
RefSeq:NP_565586.1scanprosite:PS00870scanprosite:PS00871SMART:SM00382
SMART:SM01086SMR:Q8VYJ7STRING:3702.AT2G25140.1SUPFAM:SSF52540
SUPFAM:SSF81923SwissPalm:Q8VYJ7TAIR:AT2G25140tair10-symbols:CLPB-M
tair10-symbols:CLPB4tair10-symbols:HSP98.7TIGRfam:TIGR03346TIGRFAMs:TIGR03346
UniGene:At.28343UniProt:Q8VYJ7
Coordinates (TAIR10) chr2:-:10697877..10701998
Molecular Weight (calculated) 108669.00 Da
IEP (calculated) 6.97
GRAVY (calculated) -0.40
Length 964 amino acids
Sequence (TAIR10)
(BLAST)
001: MALRRLSKSV SSAIKAQYTL SRPSPLLRSR SLSSSPHYTS IGRPTNSFIG KINNSSITHA TTTHGQLFPL SSPRRFCTTT AQVNQNEFTE MAWEGLINAF
101: DAARESKQQI VESEHLMKAL LEQKDGMARK IFTKAGIDNS SVLQATDLFI SKQPTVSDAS GQRLGSSLSV ILENAKRHKK DMLDSYVSVE HFLLAYYSDT
201: RFGQEFFRDM KLDIQVLKDA IKDVRGDQRV TDRNPESKYQ ALEKYGNDLT EMARRGKLDP VIGRDDEIRR CIQILCRRTK NNPVIIGEPG VGKTAIAEGL
301: AQRIVRGDVP EPLMNRKLIS LDMGSLLAGA KFRGDFEERL KAVMKEVSAS NGQTILFIDE IHTVVGAGAM DGAMDASNLL KPMLGRGELR CIGATTLTEY
401: RKYIEKDPAL ERRFQQVLCV QPSVEDTISI LRGLRERYEL HHGVTISDSA LVSAAVLADR YITERFLPDK AIDLVDEAGA KLKMEITSKP TELDGIDRAV
501: IKLEMEKLSL KNDTDKASKE RLQKIENDLS TLKQKQKELN VQWEKEKSLM TKIRSFKEEI DRVNLEIESA EREYDLNRAA ELKYGTLLSL QRQLEEAEKN
601: LTNFRQFGQS LLREVVTDLD IAEIVSKWTG IPLSNLQQSE REKLVMLEEV LHHRVIGQDM AVKSVADAIR RSRAGLSDPN RPIASFMFMG PTGVGKTELA
701: KALAGYLFNT ENAIVRVDMS EYMEKHSVSR LVGAPPGYVG YEEGGQLTEV VRRRPYSVVL FDEIEKAHPD VFNILLQLLD DGRITDSQGR TVSFKNCVVI
801: MTSNIGSHHI LETLRNNEDS KEAVYEIMKR QVVELARQNF RPEFMNRIDE YIVFQPLDSN EISKIVELQM RRVKNSLEQK KIKLQYTKEA VDLLAQLGFD
901: PNYGARPVKR VIQQMVENEI AVGILKGDFA EEDTVLVDVD HLASDNKLVI KKLESNASAE EMAA
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)