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AT2G21550.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plasma membrane 0.992
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : Bifunctional dihydrofolate reductase/thymidylate synthase
Curator
Summary (TAIR10)
Computational
Description (TAIR10)
Bifunctional dihydrofolate reductase/thymidylate synthase; FUNCTIONS IN: thymidylate synthase activity, dihydrofolate reductase activity; INVOLVED IN: oxidation reduction, glycine biosynthetic process, one-carbon metabolic process, nucleotide biosynthetic process, dTMP biosynthetic process; EXPRESSED IN: stem, hypocotyl, root; CONTAINS InterPro DOMAIN/s: Dihydrofolate reductase domain (InterPro:IPR001796), Dihydrofolate reductase conserved site (InterPro:IPR017925), Bifunctional dihydrofolate reductase/thymidylate synthase (InterPro:IPR012262), Thymidylate synthase (InterPro:IPR000398); BEST Arabidopsis thaliana protein match is: thymidylate synthase 1 (TAIR:AT2G16370.1); Has 12633 Blast hits to 12576 proteins in 2517 species: Archae - 33; Bacteria - 8296; Metazoa - 499; Fungi - 419; Plants - 87; Viruses - 227; Other Eukaryotes - 3072 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT2G21550-MONOMEReggNOG:COG0207eggNOG:COG0262eggNOG:ENOG410JTTJ
eggNOG:KOG0673eggNOG:KOG1324EMBL:AC007119EMBL:CP002685
EnsemblPlants:AT2G21550EnsemblPlants:AT2G21550.1entrez:816694Gene3D:3.30.572.10
Gene3D:3.40.430.10GeneID:816694GO:GO:0004146GO:GO:0004799
GO:GO:0006231GO:GO:0006545GO:GO:0006730GO:GO:0046654
Gramene:AT2G21550.1gramene_pathway:1.5.1.3gramene_pathway:2.1.1.45gramene_pathway:PWY-3742
gramene_pathway:PWY-3841gramene_pathway:PWY0-166gramene_plant_reactome:1119265gramene_plant_reactome:6874283
hmmpanther:PTHR11548hmmpanther:PTHR11548:SF2HOGENOM:HOG000257901InterPro:IPR000398
InterPro:IPR001796InterPro:IPR012262InterPro:IPR017925InterPro:IPR023451
InterPro:IPR024072KEGG:00240+2.1.1.45KEGG:00670+1.5.1.3KEGG:00670+1.5.1.3+2.1.1.45
KEGG:00670+2.1.1.45KEGG:00790+1.5.1.3KEGG:ath:AT2G21550OMA:FGVNATE
Pfam:PF00186Pfam:PF00303Pfscan:PS51330PhylomeDB:Q9SIK4
PIR:F84602PIRSF:PIRSF000389PRINTS:PR00108PROSITE:PS00075
PROSITE:PS51330Proteomes:UP000006548Reactome:R-ATH-113510Reactome:R-ATH-500753
Reactome:R-ATH-69205RefSeq:NP_179750.1scanprosite:PS00075SMR:Q9SIK4
STRING:3702.AT2G21550.1SUPFAM:SSF53597SUPFAM:SSF55831TAIR:AT2G21550
TIGRfam:TIGR03284TIGRFAMs:TIGR03284UniGene:At.50088UniPathway:UPA00077
unipathway:UPA00575UniProt:Q9SIK4
Coordinates (TAIR10) chr2:+:9227209..9230189
Molecular Weight (calculated) 55324.10 Da
IEP (calculated) 6.10
GRAVY (calculated) -0.21
Length 492 amino acids
Sequence (TAIR10)
(BLAST)
001: MASTGETICN NGQSAVSVTR RRSYQVVIAA TRDMGLGMDM KLPWDLPSEY QFFQDVTTRT SDPTKRNATI MGRKSWESTP LEIRPLPGRL NIVLTKSSCH
101: NIAIDENVLV SSSMESALEL LATEPYSLSI EKVFVIGGGE LLRNYMNASI CDAIHLTEID ISVPCDAFAP RVDTSLYRPW YSSFPVVENG IRYSFNTYVR
201: RKDAIVGSGE KKSVAESDLK EYSFLPKMVF ERHEEFGYLN LVQNIISSGD MNDNSTLSKF GCQMRFNLRK TFPLLTTKKI FWLGVVEEIL QLISGSNNPK
301: ENGSHIWDTD EAKEYLDSFG VNATEEDGDN PFLHGLHWKH CDARFVIQEF SQLSDVINKI KNNPHDQRIM LAACNPLDFK LSVSPCHTFT QFYVANGEVS
401: CQIYQSSTEA SIGIPFSIAT YSLLTCIIAH VCDLGAGDFI HVIGQAYINK AHVKAIQKQL QISPKPFPIL KINPEKKKMD NFEASDLELM RI
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)