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AT2G04450.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
extracellular 0.981
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:28865150 (2017): extracellular region plant-type cell wall
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : nudix hydrolase homolog 6
Curator
Summary (TAIR10)
Encodes a protein with NADH pyrophosphatase activity. Although this protein was also shown to have ADP-ribose diphosphatase activity in vitro, mutant analyses suggest that NUDX6 is involved in NADH metabolism in vivo.
Computational
Description (TAIR10)
nudix hydrolase homolog 6 (NUDT6); FUNCTIONS IN: hydrolase activity, ADP-ribose diphosphatase activity, NAD or NADH binding, NADH pyrophosphatase activity; INVOLVED IN: response to other organism, positive regulation of salicylic acid mediated signaling pathway; LOCATED IN: cytosol; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: NUDIX hydrolase domain-like (InterPro:IPR015797), NUDIX hydrolase, conserved site (InterPro:IPR020084), Nudix hydrolase 6-like (InterPro:IPR003293), NUDIX hydrolase domain (InterPro:IPR000086); BEST Arabidopsis thaliana protein match is: MutT/nudix family protein (TAIR:AT4G12720.3); Has 2998 Blast hits to 2996 proteins in 719 species: Archae - 33; Bacteria - 1649; Metazoa - 236; Fungi - 25; Plants - 166; Viruses - 14; Other Eukaryotes - 875 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT2G04450-MONOMERBioCyc:MetaCyc:AT2G04450-MONOMERBioGrid:386DNASU:814985
EC:3.6.1.-EC:3.6.1.13EC:3.6.1.22eggNOG:ENOG410Z4GH
eggNOG:KOG0648EMBL:AC006951EMBL:CB185816EMBL:CP002685
EnsemblPlants:AT2G04450EnsemblPlants:AT2G04450.1entrez:814985Gene3D:3.90.79.10
GeneID:814985Genevisible:Q9SJC4GO:GO:0000210GO:GO:0035529
GO:GO:0046872GO:GO:0047631GO:GO:0051287GO:GO:0051707
GO:GO:0080151Gramene:AT2G04450.1hmmpanther:PTHR13994hmmpanther:PTHR13994:SF10
HOGENOM:HOG000240943InParanoid:Q9SJC4InterPro:IPR000086InterPro:IPR003293
InterPro:IPR015797InterPro:IPR020084KEGG:00230+3.6.1.-KEGG:00332+3.6.1.-
KEGG:00790+3.6.1.-KEGG:ath:AT2G04450OMA:FMANICLPaxDb:Q9SJC4
Pfam:PF00293Pfam:Q9SJC4Pfscan:PS51462PhylomeDB:Q9SJC4
PIR:G84457PRIDE:Q9SJC4PRINTS:PR01356PRO:PR:Q9SJC4
PROSITE:PS00893PROSITE:PS51462ProteinModelPortal:Q9SJC4Proteomes:UP000006548
RefSeq:NP_178526.1scanprosite:PS00893SMR:Q9SJC4STRING:3702.AT2G04450.1
SUPFAM:SSF55811TAIR:AT2G04450tair10-symbols:ATNUDT6tair10-symbols:ATNUDX6
tair10-symbols:NUDT6tair10-symbols:NUDX6UniGene:At.41308UniProt:Q9SJC4
Coordinates (TAIR10) chr2:+:1543710..1545319
Molecular Weight (calculated) 31915.20 Da
IEP (calculated) 4.99
GRAVY (calculated) -0.27
Length 283 amino acids
Sequence (TAIR10)
(BLAST)
001: MDNEDQESLL LQGVPDNYGG VKVNLTEPMT IEDFVPKLRA SLVYWSNQGT KGIWLKLADG LDNLIAPAKA EGFVCHHAER EYTMLTSWIA DVPSTLPANA
101: SHRIGVGAFV LNKKTKEVLV VQEIDGHFKG TGVWKLPTGV VKEGENIWEG ALREVEEETG IKTKFVEVLA FRESHQAFLE IKTDIFFLCE LEPTTFEIKK
201: QDSEILAAKW MPIEEYVNQP WNQKKELFRF MANICLKRLQ EMEYMGFSKV LTTTSSGKES YLYCNTDHAN LLNATRGLAS TSG
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)