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AT1G70140.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plasma membrane 1.000
What is SUBAcon?
Predictors External Curations
AmiGO : plasma membrane 16313636
SwissProt : plasma membrane 16381842
TAIR : plasma membrane 17317660
TAIR : plasma membrane 16313636
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:16313636 (2005): cytosol cell plate
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : formin 8
Curator
Summary (TAIR10)
Encodes a group I formin. Binds to F-actin barbed ends. Has severing actin filaments activity. Binds profilin. Involved in the initiation and tip growth of root hairs through regulation of actin cytoskeleton.
Computational
Description (TAIR10)
formin 8 (FH8); FUNCTIONS IN: actin binding, profilin binding, actin filament binding; INVOLVED IN: actin nucleation, cell tip growth; LOCATED IN: cell-cell junction, plasma membrane; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Actin-binding FH2/DRF autoregulatory (InterPro:IPR003104), Actin-binding FH2 (InterPro:IPR015425); BEST Arabidopsis thaliana protein match is: formin homologue 4 (TAIR:AT1G24150.1); Has 22376 Blast hits to 12386 proteins in 831 species: Archae - 31; Bacteria - 2621; Metazoa - 7710; Fungi - 2231; Plants - 6132; Viruses - 1038; Other Eukaryotes - 2613 (source: NCBI BLink).
Protein Annotations
BioGrid:28571eggNOG:ENOG410ISMMeggNOG:ENOG410YCG5EMBL:AC002062
EMBL:CP002684EnsemblPlants:AT1G70140EnsemblPlants:AT1G70140.1entrez:843350
GeneID:843350Genevisible:O04532GO:GO:0003779GO:GO:0005522
GO:GO:0005886GO:GO:0005911GO:GO:0009932GO:GO:0016021
GO:GO:0045010GO:GO:0051015Gramene:AT1G70140.1hmmpanther:PTHR23213
hmmpanther:PTHR23213:SF239HOGENOM:HOG000112582InParanoid:O04532InterPro:IPR015425
iPTMnet:O04532KEGG:ath:AT1G70140OMA:FLFRANYPaxDb:O04532
Pfam:O04532Pfam:PF02181Pfscan:PS51444PhylomeDB:O04532
PIR:B96724PRIDE:O04532PRO:PR:O04532PROSITE:PS51444
ProteinModelPortal:O04532Proteomes:UP000006548RefSeq:NP_177171.1SMART:SM00498
SMR:O04532STRING:3702.AT1G70140.1SUPFAM:SSF101447TAIR:AT1G70140
tair10-symbols:ATFH8tair10-symbols:FH8TMHMM:TMhelixUniGene:At.35341
UniProt:O04532
Coordinates (TAIR10) chr1:-:26412688..26415048
Molecular Weight (calculated) 83607.40 Da
IEP (calculated) 9.54
GRAVY (calculated) -0.37
Length 760 amino acids
Sequence (TAIR10)
(BLAST)
001: MAAMFNHPWP NLTLIYFFFI VVLPFQSLSQ FDSPQNIETF FPISSLSPVP PPLLPPSSNP SPPSNNSSSS DKKTITKAVL ITAASTLLVA GVFFFCLQRC
101: IIARRRRDRV GPVRVENTLP PYPPPPMTSA AVTTTTLARE GFTRFGGVKG LILDENGLDV LYWRKLQSQR ERSGSFRKQI VTGEEEDEKE VIYYKNKKKT
201: EPVTEIPLLR GRSSTSHSVI HNEDHQPPPQ VKQSEPTPPP PPPSIAVKQS APTPSPPPPI KKGSSPSPPP PPPVKKVGAL SSSASKPPPA PVRGASGGET
301: SKQVKLKPLH WDKVNPDSDH SMVWDKIDRG SFSFDGDLME ALFGYVAVGK KSPEQGDEKN PKSTQIFILD PRKSQNTAIV LKSLGMTREE LVESLIEGND
401: FVPDTLERLA RIAPTKEEQS AILEFDGDTA KLADAETFLF HLLKSVPTAF TRLNAFLFRA NYYPEMAHHS KCLQTLDLAC KELRSRGLFV KLLEAILKAG
501: NRMNAGTARG NAQAFNLTAL LKLSDVKSVD GKTSLLNFVV EEVVRSEGKR CVMNRRSHSL TRSGSSNYNG GNSSLQVMSK EEQEKEYLKL GLPVVGGLSS
601: EFSNVKKAAC VDYETVVATC SALAVRAKDA KTVIGECEDG EGGRFVKTMM TFLDSVEEEV KIAKGEERKV MELVKRTTDY YQAGAVTKGK NPLHLFVIVR
701: DFLAMVDKVC LDIMRNMQRR KVGSPISPSS QRNAVKFPVL PPNFMSDRAW SDSGGSDSDM
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)