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AT1G65060.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
peroxisome 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : 4-coumarate:CoA ligase 3
Curator
Summary (TAIR10)
encodes an isoform of 4-coumarate:CoA ligase (4CL), which is involved in the last step of the general phenylpropanoid pathway. mRNA levels are not induced in response to wounding or to fungal infection by P. parasitica. mRNA is expressed in flowers, to a lesser degree in mature leaves and siliques and marginally in seedling roots and bolting stems of mature plants. The catalytic efficiency was in the following (descending) order: p-coumaric acid, caffeic acid, ferulic acid, cinnamic acid and 5-OH-ferulic acid. At4CL3 was unable to use sinapic acid as substrate.
Computational
Description (TAIR10)
4-coumarate:CoA ligase 3 (4CL3); CONTAINS InterPro DOMAIN/s: AMP-binding, conserved site (InterPro:IPR020845), AMP-dependent synthetase/ligase (InterPro:IPR000873); BEST Arabidopsis thaliana protein match is: 4-coumarate:CoA ligase 2 (TAIR:AT3G21240.1); Has 85516 Blast hits to 77968 proteins in 3765 species: Archae - 1155; Bacteria - 54010; Metazoa - 3516; Fungi - 4668; Plants - 2834; Viruses - 1; Other Eukaryotes - 19332 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT1G65060-MONOMERBioCyc:ARA:GQT-2318-MONOMERBioCyc:MetaCyc:AT1G65060-MONOMEREC:6.2.1.12
eggNOG:COG0318eggNOG:KOG1176EMBL:AC009360EMBL:AF106087
EMBL:AF106088EMBL:AY058083EMBL:AY090306EMBL:AY376730
EMBL:CP002684EnsemblPlants:AT1G65060EnsemblPlants:AT1G65060.1entrez:842814
ExpressionAtlas:Q9S777GeneID:842814Genevisible:Q9S777GO:GO:0005524
GO:GO:0009698GO:GO:0010584GO:GO:0016207gramene_pathway:6.2.1.12
gramene_pathway:6.2.1.34gramene_pathway:PWY-1121gramene_pathway:PWY-361gramene_pathway:PWY-5868
gramene_pathway:PWY1F-FLAVSYNgramene_pathway:PWY4FS-9gramene_plant_reactome:1119531gramene_plant_reactome:6876097
hmmpanther:PTHR24096hmmpanther:PTHR24096:SF169HOGENOM:HOG000230009InParanoid:Q9S777
InterPro:IPR000873InterPro:IPR020845InterPro:IPR025110iPTMnet:Q9S777
KEGG:ath:AT1G65060KO:K01904OMA:PSAYDYPPaxDb:Q9S777
Pfam:PF00501Pfam:PF13193Pfam:Q9S777PhylomeDB:Q9S777
PIR:D96674PRIDE:Q9S777PRO:PR:Q9S777PROSITE:PS00455
ProteinModelPortal:Q9S777Proteomes:UP000006548Reactome:R-ATH-75105RefSeq:NP_176686.1
SABIO-RK:Q9S777scanprosite:PS00455SMR:Q9S777STRING:3702.AT1G65060.1
SUPFAM:SSF56801TAIR:AT1G65060tair10-symbols:4CL3UniGene:At.11514
UniPathway:UPA00372UniProt:Q9S777
Coordinates (TAIR10) chr1:-:24167385..24171457
Molecular Weight (calculated) 61314.00 Da
IEP (calculated) 6.31
GRAVY (calculated) -0.02
Length 561 amino acids
Sequence (TAIR10)
(BLAST)
001: MITAALHEPQ IHKPTDTSVV SDDVLPHSPP TPRIFRSKLP DIDIPNHLPL HTYCFEKLSS VSDKPCLIVG STGKSYTYGE THLICRRVAS GLYKLGIRKG
101: DVIMILLQNS AEFVFSFMGA SMIGAVSTTA NPFYTSQELY KQLKSSGAKL IITHSQYVDK LKNLGENLTL ITTDEPTPEN CLPFSTLITD DETNPFQETV
201: DIGGDDAAAL PFSSGTTGLP KGVVLTHKSL ITSVAQQVDG DNPNLYLKSN DVILCVLPLF HIYSLNSVLL NSLRSGATVL LMHKFEIGAL LDLIQRHRVT
301: IAALVPPLVI ALAKNPTVNS YDLSSVRFVL SGAAPLGKEL QDSLRRRLPQ AILGQGYGMT EAGPVLSMSL GFAKEPIPTK SGSCGTVVRN AELKVVHLET
401: RLSLGYNQPG EICIRGQQIM KEYLNDPEAT SATIDEEGWL HTGDIGYVDE DDEIFIVDRL KEVIKFKGFQ VPPAELESLL INHHSIADAA VVPQNDEVAG
501: EVPVAFVVRS NGNDITEEDV KEYVAKQVVF YKRLHKVFFV ASIPKSPSGK ILRKDLKAKL C
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)