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AT1G59900.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
mitochondrion 1.000
ASURE: mitochondrion
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31975158 (2020): plastid
  • PMID:31911558 (2020): mitochondrion
  • PMID:31871212 (2020): mitochondrion
  • PMID:31818904 (2020): mitochondrion
  • PMID:31615849 (2019): plastid plastid thylakoid
  • PMID:31520498 (2020): mitochondrion
  • PMID:31186290 (2019): cytosol None
  • PMID:31023727 (2019): mitochondrion
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:30135097 (2018): plastid
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:27943495 (2017): mitochondrion
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:24727099 (2014): mitochondrion
  • PMID:24361574 (2014): plastid plastid stroma
  • PMID:23750852 (2013): mitochondrion
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:22540835 (2012): mitochondrion
  • PMID:21841088 (2011): mitochondrion
  • PMID:21472856 (2011): mitochondrion
  • PMID:21311031 (2011): mitochondrion
  • PMID:21296373 (2011): mitochondrion
  • PMID:19688752 (2009): mitochondrion
  • PMID:18385124 (2008): mitochondrion
  • PMID:14671022 (2004): mitochondrion
  • PMID:11743115 (2001): mitochondrion
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : pyruvate dehydrogenase complex E1 alpha subunit
Curator
Summary (TAIR10)
encodes the e1 alpha subunit of the pyruvate dehydrogenase complex (PDC)
Computational
Description (TAIR10)
pyruvate dehydrogenase complex E1 alpha subunit (E1 ALPHA); FUNCTIONS IN: oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor, pyruvate dehydrogenase (acetyl-transferring) activity; INVOLVED IN: response to cadmium ion, metabolic process; LOCATED IN: cytosol, mitochondrion, nucleus; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Dehydrogenase, E1 component (InterPro:IPR001017), Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y (InterPro:IPR017597); BEST Arabidopsis thaliana protein match is: Thiamin diphosphate-binding fold (THDP-binding) superfamily protein (TAIR:AT1G24180.1); Has 9893 Blast hits to 9890 proteins in 1845 species: Archae - 125; Bacteria - 6023; Metazoa - 522; Fungi - 292; Plants - 213; Viruses - 0; Other Eukaryotes - 2718 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT1G59900-MONOMERBioGrid:27509EC:1.2.4.1eggNOG:COG1071
eggNOG:KOG0225EMBL:AC007258EMBL:AF360306EMBL:AY087667
EMBL:BT000974EMBL:CP002684EMBL:U21214EnsemblPlants:AT1G59900
EnsemblPlants:AT1G59900.1entrez:842284Gene3D:3.40.50.970GeneID:842284
Genevisible:P52901GO:GO:0004739GO:GO:0005634GO:GO:0005739
GO:GO:0005759GO:GO:0005829GO:GO:0006086GO:GO:0006096
GO:GO:0046686Gramene:AT1G59900.1gramene_pathway:1.2.4.1gramene_pathway:PYRUVDEHYD-PWY
hmmpanther:PTHR11516hmmpanther:PTHR11516:SF40HOGENOM:HOG000281336InParanoid:P52901
IntAct:P52901InterPro:IPR001017InterPro:IPR017597InterPro:IPR029061
iPTMnet:P52901KEGG:00010+1.2.4.1KEGG:00020+1.2.4.1KEGG:00620+1.2.4.1
KEGG:ath:AT1G59900KO:K00161ncoils:CoilOMA:PYSVETT
PaxDb:P52901Pfam:P52901Pfam:PF00676PhylomeDB:P52901
PIR:B96623PIR:JC4358PRIDE:P52901PRO:PR:P52901
ProteinModelPortal:P52901Proteomes:UP000006548Reactome:R-ATH-70268RefSeq:NP_176198.1
SMR:P52901STRING:3702.AT1G59900.1SUPFAM:SSF52518SWISS-2DPAGE:P52901
TAIR:AT1G59900tair10-symbols:AT-E1 ALPHAtair10-symbols:E1 ALPHATIGRfam:TIGR03182
TIGRFAMs:TIGR03182UniGene:At.23186UniProt:P52901
Coordinates (TAIR10) chr1:+:22051368..22053660
Molecular Weight (calculated) 43061.50 Da
IEP (calculated) 7.54
GRAVY (calculated) -0.33
Length 389 amino acids
Sequence (TAIR10)
(BLAST)
001: MALSRLSSRS NIITRPFSAA FSRLISTDTT PITIETSLPF TAHLCDPPSR SVESSSQELL DFFRTMALMR RMEIAADSLY KAKLIRGFCH LYDGQEAVAI
101: GMEAAITKKD AIITAYRDHC IFLGRGGSLH EVFSELMGRQ AGCSKGKGGS MHFYKKESSF YGGHGIVGAQ VPLGCGIAFA QKYNKEEAVT FALYGDGAAN
201: QGQLFEALNI SALWDLPAIL VCENNHYGMG TAEWRAAKSP SYYKRGDYVP GLKVDGMDAF AVKQACKFAK QHALEKGPII LEMDTYRYHG HSMSDPGSTY
301: RTRDEISGVR QERDPIERIK KLVLSHDLAT EKELKDMEKE IRKEVDDAIA KAKDCPMPEP SELFTNVYVK GFGTESFGPD RKEVKASLP
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)