suba logo
AT1G12220.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

.
SUBAcon:
plasma membrane 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : Disease resistance protein (CC-NBS-LRR class) family
Curator
Summary (TAIR10)
Resistance gene, mediates resistance against the bacterial pathogen Pseudomonas syringae. Contains a putative nucleotide binding site composed of kinase-1a (or P-loop), kinase-2a, and putative kinase-3a domains, 13 imperfect leucine-rich repeats, a potential leucine zipper, and two uncharacterized motifs that are well conserved in products of previously isolated R genes. Confers resistance to Pseudomonas syringae strains that express avrPphB.
Computational
Description (TAIR10)
RESISTANT TO P. SYRINGAE 5 (RPS5); CONTAINS InterPro DOMAIN/s: Leucine-rich repeat-containing protein (InterPro:IPR015766), NB-ARC (InterPro:IPR002182), Disease resistance protein (InterPro:IPR000767); BEST Arabidopsis thaliana protein match is: LRR and NB-ARC domains-containing disease resistance protein (TAIR:AT1G12280.1); Has 17406 Blast hits to 16115 proteins in 670 species: Archae - 23; Bacteria - 856; Metazoa - 2611; Fungi - 230; Plants - 13400; Viruses - 0; Other Eukaryotes - 286 (source: NCBI BLink).
Protein Annotations
BioGrid:23015DIP:DIP-60862NeggNOG:COG4886eggNOG:KOG4658
EMBL:AC022522EMBL:AF039379EMBL:AF074916EMBL:BT010583
EMBL:CP002684EMBL:U97219EMBL:U97221EnsemblPlants:AT1G12220
EnsemblPlants:AT1G12220.1EnsemblPlants:AT1G12220.2entrez:837775ExpressionAtlas:O64973
Gene3D:3.40.50.300Gene3D:3.80.10.10GeneID:837775Genevisible:O64973
GO:GO:0000166GO:GO:0005524GO:GO:0005622GO:GO:0005886
GO:GO:0006952GO:GO:0007165GO:GO:0008219GO:GO:0009626
GO:GO:0009816GO:GO:0038023GO:GO:0043531Gramene:AT1G12220.1
Gramene:AT1G12220.2hmmpanther:PTHR23155hmmpanther:PTHR23155:SF639HOGENOM:HOG000238348
InParanoid:O64973InterPro:IPR001611InterPro:IPR002182InterPro:IPR027417
InterPro:IPR032675KEGG:ath:AT1G12220KO:K13460ncoils:Coil
OMA:VHEWCHAPaxDb:O64973Pfam:O64973Pfam:PF00931
Pfam:PF13855PhylomeDB:O64973PIR:C86257PRIDE:O64973
PRO:PR:O64973ProteinModelPortal:O64973Proteomes:UP000006548RefSeq:NP_001184970.1
RefSeq:NP_172686.1SMR:O64973SMR:Q56YM8STRING:3702.AT1G12220.1
SUPFAM:SSF52058SUPFAM:SSF52540TAIR:AT1G12220tair10-symbols:RPS5
UniGene:At.42084UniProt:O64973UniProt:Q56YM8
Coordinates (TAIR10) chr1:+:4145011..4147680
Molecular Weight (calculated) 101808.00 Da
IEP (calculated) 7.17
GRAVY (calculated) -0.15
Length 889 amino acids
Sequence (TAIR10)
(BLAST)
001: MGGCFSVSLP CDQVVSQFSQ LLCVRGSYIH NLSKNLASLQ KAMRMLKARQ YDVIRRLETE EFTGRQQRLS QVQVWLTSVL IIQNQFNDLL RSNEVELQRL
101: CLCGFCSKDL KLSYRYGKRV IMMLKEVESL SSQGFFDVVS EATPFADVDE IPFQPTIVGQ EIMLEKAWNR LMEDGSGILG LYGMGGVGKT TLLTKINNKF
201: SKIDDRFDVV IWVVVSRSST VRKIQRDIAE KVGLGGMEWS EKNDNQIAVD IHNVLRRRKF VLLLDDIWEK VNLKAVGVPY PSKDNGCKVA FTTRSRDVCG
301: RMGVDDPMEV SCLQPEESWD LFQMKVGKNT LGSHPDIPGL ARKVARKCRG LPLALNVIGE AMACKRTVHE WCHAIDVLTS SAIDFSGMED EILHVLKYSY
401: DNLNGELMKS CFLYCSLFPE DYLIDKEGLV DYWISEGFIN EKEGRERNIN QGYEIIGTLV RACLLLEEER NKSNVKMHDV VREMALWISS DLGKQKEKCI
501: VRAGVGLREV PKVKDWNTVR KISLMNNEIE EIFDSHECAA LTTLFLQKND VVKISAEFFR CMPHLVVLDL SENQSLNELP EEISELASLR YFNLSYTCIH
601: QLPVGLWTLK KLIHLNLEHM SSLGSILGIS NLWNLRTLGL RDSRLLLDMS LVKELQLLEH LEVITLDISS SLVAEPLLCS QRLVECIKEV DFKYLKEESV
701: RVLTLPTMGN LRKLGIKRCG MREIKIERTT SSSSRNKSPT TPCFSNLSRV FIAKCHGLKD LTWLLFAPNL TFLEVGFSKE VEDIISEEKA EEHSATIVPF
801: RKLETLHLFE LRGLKRIYAK ALHFPCLKVI HVEKCEKLRK LPLDSKSGIA GEELVIYYGE REWIERVEWE DQATQLRFLP SSRWRWRET
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)