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AT5G58140.4
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plasma membrane 1.000
ASURE: plasma membrane
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : phototropin 2
Curator
Summary (TAIR10)
Membrane-bound protein serine/threonine kinase that functions as blue light photoreceptor in redundancy with PHO1. Involved in stomatal opening, chloroplast movement and phototropism. Mediates blue light-induced growth enhancements. PHOT1 and PHOT2 mediate blue light-dependent activation of the plasma membrane H+-ATPase in guard cell protoplasts. PHOT2 possesses two LOV (LOV1 and LOV2, for light-oxygen-voltage-sensing) domains involved in FMN-binding and a C-terminus forming a serine/threonine kinase domain. LOV2 acts as an inhibitor of phototropin kinase in the dark, and light cancels the inhibition through cysteine-FMN adduct formation. LOV1 in contrast acts as an attenuator of photoactivation. Localized to the Golgi apparatus under the induction of blue light.
Computational
Description (TAIR10)
phototropin 2 (PHOT2); FUNCTIONS IN: protein serine/threonine kinase activity, FMN binding, kinase activity, blue light photoreceptor activity; INVOLVED IN: in 7 processes; LOCATED IN: Golgi apparatus, plasma membrane, membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: PAC motif (InterPro:IPR001610), Protein kinase, ATP binding site (InterPro:IPR017441), PAS fold (InterPro:IPR013767), Serine/threonine-protein kinase domain (InterPro:IPR002290), PAS (InterPro:IPR000014), PAS-associated, C-terminal (InterPro:IPR000700), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Protein kinase, catalytic domain (InterPro:IPR000719); BEST Arabidopsis thaliana protein match is: phototropin 1 (TAIR:AT3G45780.2); Has 25181 Blast hits to 21357 proteins in 1460 species: Archae - 236; Bacteria - 6754; Metazoa - 8411; Fungi - 2718; Plants - 3113; Viruses - 9; Other Eukaryotes - 3940 (source: NCBI BLink).
Protein Annotations
eggNOG:COG2202eggNOG:ENOG410IH6NEMBL:CP002688EnsemblPlants:AT5G58140
EnsemblPlants:AT5G58140.4entrez:835926ExpressionAtlas:F4KDJ3GeneID:835926
GO:GO:0000155GO:GO:0005524GO:GO:0005622Gramene:AT5G58140.4
hmmpanther:PTHR24351hmmpanther:PTHR24351:SF81InterPro:IPR000014InterPro:IPR000700
InterPro:IPR000719InterPro:IPR001610InterPro:IPR011009InterPro:IPR017441
KEGG:ath:AT5G58140PaxDb:F4KDJ3Pfam:PF00069Pfam:PF13426
Pfscan:PS50011Pfscan:PS50112Pfscan:PS50113PRIDE:F4KDJ3
PROSITE:PS00107PROSITE:PS50011PROSITE:PS50112PROSITE:PS50113
ProteinModelPortal:F4KDJ3Proteomes:UP000006548RefSeq:NP_568874.2scanprosite:PS00107
SMART:SM00086SMART:SM00091SMART:SM00220SMR:F4KDJ3
STRING:3702.AT5G58140.1SUPFAM:SSF55785SUPFAM:SSF56112TAIR:AT5G58140
tair10-symbols:NPL1tair10-symbols:PHOT2TIGRfam:TIGR00229TIGRFAMs:TIGR00229
UniGene:At.22044UniGene:At.72500UniProt:F4KDJ3
Coordinates (TAIR10) chr5:+:23524771..23528541
Molecular Weight (calculated) 77364.30 Da
IEP (calculated) 7.60
GRAVY (calculated) -0.68
Length 689 amino acids
Sequence (TAIR10)
(BLAST)
001: MERPRAPPSP LNDAESLSER RSLEIFNPSS GKETHGSTSS SSKPPLDGNN KGSSSKWMEF QDSAKITERT AEWGLSAVKP DSGDDGISFK LSSEVERSKN
101: MSRRSSEEST SSESGAFPRV SQELKTALST LQQTFVVSDA TQPHCPIVYA SSGFFTMTGY SSKEIVGRNC RFLQGPDTDK NEVAKIRDCV KNGKSYCGRL
201: LNYKKDGTPF WNLLTVTPIK DDQGNTIKFI GMQVEVSKYT EGVNDKALRP NGLSKSLIRY DARQKEKALD SITEVVQTIR HRKSQVQESV SNDTMVKPDS
301: STTPTPGRQT RQSDEASKSF RTPGRVSTPT GSKLKSSNNR HEDLLRMEPE ELMLSTEVIG QRDSWDLSDR ERDIRQGIDL ATTLERIEKN FVISDPRLPD
401: NPIIFASDSF LELTEYSREE ILGRNCRFLQ GPETDQATVQ KIRDAIRDQR EITVQLINYT KSGKKFWNLF HLQPMRDQKG ELQYFIGVQL DGSDHVEPLQ
501: NRLSERTEMQ SSKLVKATAT NVDEAVRELP DANTRPEDLW AAHSKPVYPL PHNKESTSWK AIKKIQASGE TVGLHHFKPI KPLGSGDTGS VHLVELKGTG
601: ELYAMKAMEK TMMLNRNKAH RACIEREIIS LLDHPFLPTL YASFQTSTHV CLITDFCPGG ELFALLDRQP MKILTEDSAR FPLFLNLNV
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)