AT5G15410.2
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:plasma membrane 0.712 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : Cyclic nucleotide-regulated ion channel family protein | ||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
'defense, no death' gene (DND1) encodes a mutated cyclic nucleotide-gated cation channel; Same as CNGC2 (article ID 229): Cyclic nucleotide gated channel, activated by cAMP, conducts K+ and other monovalent cations but excludes Na+, does not contain the GYG amino acid sequence found in other channels with this conductivity profile. Conducts Ca2+ into cells which is linked to the generation of NO and the NO signaling pathway involved in the innate immune response to pathogens. | ||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
DEFENSE NO DEATH 1 (DND1); CONTAINS InterPro DOMAIN/s: Cyclic nucleotide-binding (InterPro:IPR000595), Cyclic nucleotide-binding-like (InterPro:IPR018490), RmlC-like jelly roll fold (InterPro:IPR014710); BEST Arabidopsis thaliana protein match is: cyclic nucleotide-gated cation channel 4 (TAIR:AT5G54250.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr5:-:5003460..5006512 | ||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 83093.80 Da | ||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 9.88 | ||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | 0.01 | ||||||||||||||||||||||||||||||||||||||||
| Length | 725 amino acids | ||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MQFLIISLEW IGLFSDKFRR QTTGIDENSN LQINGGDSSS SGSDETPVLS SVECYACTQV GVPAFHSTSC DQAHAPEWRA SAGSSLVPIQ EGSVPNPART 101: RFRRLKGPFG EVLDPRSKRV QRWNRALLLA RGMALAVDPL FFYALSIGRT TGPACLYMDG AFAAVVTVLR TCLDAVHLWH VWLQFRLAYV SRESLVVGCG 201: KLVWDPRAIA SHYARSLTGF WFDVIVILPV PQAVFWLVVP KLIREEKVKL IMTILLLIFL FQFLPKIYHC ICLMRRMQKV TGYIFGTIWW GFALNLIAYF 301: IASHVAGGCW YVLAIQRVAS CIRQQCMRTG NCNLSLACKE EVCYQFVSPT STVGYPCLSG NLTSVVNKPM CLDSNGPFRY GIYRWALPVI SSNSLAVKIL 401: YPIFWGLMTL STFANDLEPT SNWLEVIFSI VMVLSGLLLF TLLIGNIQVF LHAVMAKKRK MQIRCRDMEW WMKRRQLPSR LRQRVRRFER QRWNALGGED 501: ELELIHDLPP GLRRDIKRYL CFDLINKVPL FRGMDDLILD NICDRAKPRV FSKDEKIIRE GDPVQRMIFI MRGRVKRIQS LSKGVLATST LEPGGYLGDE 601: LLSWCLRRPF LDRLPPSSAT FVCLENIEAF SLGSEDLRYI TDHFRYKFAN ERLKRTARYY SSNWRTWAAV NIQMAWRRRR KRTRGENIGG SMSPVSENSI 701: EGNSERRLLQ YAAMFMSIRP HDHLE |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)