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AT5G14200.3
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plastid 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : isopropylmalate dehydrogenase 1
Curator
Summary (TAIR10)
The AtIMD1 is one out of 3 genes encoding the enzyme 3-isopropylmalate dehydrogenase involved in leucine biosynthesis in Arabidopsis. Its subcellular location has been targeted to plastids. Encodes methylthioalkylmalate dehydrogenase. Involved in glucosinolate biosynthesis, in methionine chain elongation.
Computational
Description (TAIR10)
isopropylmalate dehydrogenase 1; FUNCTIONS IN: 3-isopropylmalate dehydrogenase activity; INVOLVED IN: glucosinolate biosynthetic process, leucine biosynthetic process, response to salt stress, metabolic process; LOCATED IN: chloroplast, plastid; EXPRESSED IN: root, leaf; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: Isopropylmalate dehydrogenase (InterPro:IPR004429), Isocitrate/isopropylmalate dehydrogenase (InterPro:IPR001804), Isocitrate/isopropylmalate dehydrogenase, conserved site (InterPro:IPR019818); BEST Arabidopsis thaliana protein match is: isopropylmalate dehydrogenase 3 (TAIR:AT1G31180.1); Has 15391 Blast hits to 15391 proteins in 2664 species: Archae - 400; Bacteria - 8416; Metazoa - 576; Fungi - 851; Plants - 241; Viruses - 0; Other Eukaryotes - 4907 (source: NCBI BLink).
Protein Annotations
EC:1.1.1.85eggNOG:COG0473eggNOG:KOG0786EMBL:AK317532
EMBL:CP002688EnsemblPlants:AT5G14200EnsemblPlants:AT5G14200.3entrez:831270
ExpressionAtlas:B9DHH9Gene3D:3.40.718.10GeneID:831270GO:GO:0000287
GO:GO:0003862GO:GO:0005737GO:GO:0009098GO:GO:0051287
Gramene:AT5G14200.3gramene_pathway:1.1.1.-gramene_pathway:1.1.1.85gramene_pathway:LEUSYN-PWY
gramene_pathway:PWYQT-4450HAMAP:MF_01033hmmpanther:PTHR11835hmmpanther:PTHR11835:SF53
InterPro:IPR001804InterPro:IPR004429InterPro:IPR019818InterPro:IPR024084
KEGG:00290+1.1.1.85KEGG:00660+1.1.1.85PANTHER:PTHR11835Pfam:PF00180
PROSITE:PS00470Proteomes:UP000006548RefSeq:NP_001031880.1scanprosite:PS00470
SMART:SM01329SMR:B9DHH9STRING:3702.AT5G14200.1SUPFAM:SSF53659
TAIR:AT5G14200TIGRfam:TIGR00169TIGRFAMs:TIGR00169UniGene:At.23937
UniGene:At.6515UniPathway:UPA00048UniProt:B9DHH9
Coordinates (TAIR10) chr5:+:4576220..4577962
Molecular Weight (calculated) 41894.60 Da
IEP (calculated) 5.79
GRAVY (calculated) -0.04
Length 388 amino acids
Sequence (TAIR10)
(BLAST)
001: MAAFLQTNIS LNAIKIVPGK YSSLTDHQFR APYRIRCAAA SPGKKRYNIA LLPGDGIGPE VISVAKNVLQ KAGSLEGLEF DFKEMPVGGA ALDLVGVPLP
101: EETFTAAKLS DAILLGAIGG YKWDKNEKHL RPEMALFYLR RDLKVFANLR PATVLPQLVD ASTLKKEVAE GVDMMIVREL TGGIYFGEPR GITINENGEE
201: VGVSTEIYAA HEIDRIARVA FETARKRRGK LCSVDKANVL DASILWRKRV TALASEYPDV ELSHMYVDNA AMQLIRDPKQ FDTIVTNNIF GDILSDEASM
301: ITGSIGMLPS ASLGESGPGL FEPIHGSAPD IAGQDKANPL ATILSAAMLL KYGLGEEKAA KRIEDAVVDA LNKGFRTGDI YSPGNVCA
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)