AT5G04510.2
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:cytosol 0.983 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : 3'-phosphoinositide-dependent protein kinase 1 | ||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes 3-phosphoinositide-dependent protein kinase that contains pleckstrin homology domain and binds 3-phosphoinositides. It activates the protein kinase AGC2-1 in a phosphatidic acid dependent manner. Phosphorylates S6K1. Interacts with PID, and transphosphorylation by PDK1 increases PID autophosphorylation. | ||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
3'-phosphoinositide-dependent protein kinase 1 (PDK1); FUNCTIONS IN: 3-phosphoinositide-dependent protein kinase activity, protein binding, phosphoinositide binding, protein kinase activity, kinase activity; INVOLVED IN: positive regulation of protein kinase activity; LOCATED IN: cellular_component unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Serine/threonine-protein kinase-1, 3-phosphoinositide dependent (InterPro:IPR015746), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: 3-phosphoinositide-dependent protein kinase (TAIR:AT3G10540.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr5:+:1287235..1289231 | ||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 45289.30 Da | ||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 6.30 | ||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.39 | ||||||||||||||||||||||||||||||||||||||||
| Length | 408 amino acids | ||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MLAMEKEFDS KLVLQGNSSN GANVSRSKSF SFKAPQENFT SHDFEFGKIY GVGSYSKVVR AKKKETGTVY ALKIMDKKFI TKENKTAYVK LERIVLDQLE 101: HPGIIKLYFT FQDTSSLYMA LESCEGGELF DQITRKGRLS EDEARFYTAE VVDALEYIHS MGLIHRDIKP ENLLLTSDGH IKIADFGSVK PMQDSQITVL 201: PNAASDDKAC TFVGTAAYVP PEVLNSSPAT FGNDLWALGC TLYQMLSGTS PFKDASEWLI FQRIIARDIK FPNHFSEAAR DLIDRLLDTE PSRRPGAGSE 301: GYVALKRHPF FNGVDWKNLR SQTPPKLAPD PASQTASPER DDTHGSPWNL THIGDSLATQ NEGHSAPPTS SESSGSITRL ASIDSFDSRW WGHLSFICFL 401: GSNLVQSS |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)