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AT4G15530.5
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
cytosol 0.500
plastid 0.500
ASURE: cytosol,plastid
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : pyruvate orthophosphate dikinase
Curator
Summary (TAIR10)
Encodes a dual-targeted protein believed to act as a pyruvate, orthophosphate dikinase. These enzymes are normally associated with C4 photosynthesis which does not occur in Arabidopsis. However, PPDK may play a role in remobilizing nitrogen during leaf senescence in Arabidopsis. The product of the long transcript (.1 gene model) was shown to be targeted to the chloroplast, whereas the shorter transcript (no targeting sequence) accumulates in the cytosol. The two proteins were also found to be expressed in slightly different tissues.
Computational
Description (TAIR10)
pyruvate orthophosphate dikinase (PPDK); FUNCTIONS IN: kinase activity, pyruvate, phosphate dikinase activity; INVOLVED IN: phosphorylation, response to absence of light; LOCATED IN: cytosol, nucleus, chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: PEP-utilising enzyme, mobile domain (InterPro:IPR008279), Pyruvate, phosphate dikinase (InterPro:IPR010121), ATP-grasp fold, subdomain 1 (InterPro:IPR013815), Pyruvate phosphate dikinase, PEP/pyruvate-binding (InterPro:IPR002192), Pyruvate/Phosphoenolpyruvate kinase, catalytic core (InterPro:IPR015813), PEP-utilising enzyme, mobile region, conserved site (InterPro:IPR018274), ATP-grasp fold, subdomain 2 (InterPro:IPR013816), PEP-utilising enzyme (InterPro:IPR000121); Has 15119 Blast hits to 15038 proteins in 2560 species: Archae - 291; Bacteria - 9841; Metazoa - 12; Fungi - 19; Plants - 125; Viruses - 0; Other Eukaryotes - 4831 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT4G15530-MONOMERBioCyc:ARA:GQT-1246-MONOMERBioCyc:ARA:GQT-2597-MONOMERBioCyc:ARA:GQT-2598-MONOMER
BioCyc:ARA:GQT-2599-MONOMERBioCyc:ARA:GQT-2600-MONOMERBioGrid:12523BRENDA:2.7.11.32
EC:2.7.9.1eggNOG:COG0574eggNOG:ENOG410IIM3EMBL:AK317187
EMBL:AL161541EMBL:CP002687EMBL:Z97339EnsemblPlants:AT4G15530
EnsemblPlants:AT4G15530.5EnsemblPlants:AT4G15530.6entrez:827226ExpressionAtlas:O23404
Gene3D:3.20.20.60Gene3D:3.30.1490.20Gene3D:3.30.470.20Gene3D:3.50.30.10
GeneID:827226Genevisible:O23404GO:GO:0005524GO:GO:0005634
GO:GO:0005829GO:GO:0006090GO:GO:0009507GO:GO:0009570
GO:GO:0015979GO:GO:0016301GO:GO:0046872GO:GO:0050242
gramene_pathway:2.7.9.1gramene_pathway:PWY-6549hmmpanther:PTHR22931hmmpanther:PTHR22931:SF9
HOGENOM:HOG000039664InParanoid:O23404InterPro:IPR000121InterPro:IPR002192
InterPro:IPR008279InterPro:IPR010121InterPro:IPR013815InterPro:IPR013816
InterPro:IPR015813InterPro:IPR018274InterPro:IPR023151iPTMnet:O23404
KEGG:00620+2.7.9.1KEGG:00710+2.7.9.1KEGG:00720+2.7.9.1KEGG:ath:AT4G15530
KO:K01006OMA:VRRETNPPANTHER:PTHR22931:SF9PaxDb:O23404
Pfam:O23404Pfam:PF00391Pfam:PF01326Pfam:PF02896
PhylomeDB:O23404PIR:A71420PIRSF:PIRSF000853PRIDE:O23404
PRO:PR:O23404PROSITE:PS00370PROSITE:PS00742ProteinModelPortal:O23404
Proteomes:UP000006548RefSeq:NP_001031647.1RefSeq:NP_001078395.1RefSeq:NP_001078396.1
RefSeq:NP_001118987.1RefSeq:NP_193288.2RefSeq:NP_849391.2scanprosite:PS00370
scanprosite:PS00742SMR:O23404STRING:3702.AT4G15530.5SUPFAM:SSF51621
SUPFAM:SSF52009SUPFAM:SSF56059TAIR:AT4G15530tair10-symbols:PPDK
TIGRfam:TIGR01828TIGRFAMs:TIGR01828UniGene:At.23286UniGene:At.44851
UniProt:O23404
Coordinates (TAIR10) chr4:-:8864828..8870748
Molecular Weight (calculated) 105144.00 Da
IEP (calculated) 6.32
GRAVY (calculated) -0.17
Length 963 amino acids
Sequence (TAIR10)
(BLAST)
001: MLYIRKKMTS MIVKTTPELF KGNGVFRTDH LGENRMVSRS NRLGDGSNRF PRTGTIHCQR LSIAKTGLHR ETKARAILSP VSDPAASIAQ KRVFTFGKGR
101: SEGNKGMKSL LGGKGANLAE MASIGLSVPP GLTISTEACQ QYQIAGKKLP EGLWEEILEG LSFIERDIGA SLADPSKPLL LSVRSGAAIS MPGMMDTVLN
201: LGLNDQVVVG LAAKSGERFA YDSFRRFLDM FGDVVMGIPH AKFEEKLERM KERKGVKNDT DLSAADLKEL VEQYKSVYLE AKGQEFPSDP KKQLELAIEA
301: VFDSWDSPRA NKYRSINQIT GLKGTAVNIQ CMVFGNMGDT SGTGVLFTRN PSTGEKKLYG EFLVNAQGED VVAGIRTPED LDTMKRFMPE AYAELVENCN
401: ILERHYKDMM DIEFTVQEER LWMLQCRAGK RTGKGAVKIA VDMVGEGLVE KSSAIKMVEP QHLDQLLHPQ FHDPSGYREK VVAKGLPASP GAAVGQVVFT
501: AEEAEAWHSQ GKTVILVRTE TSPDDVGGMH AAEGILTARG GMTSHAAVVA RGWGKCCIAG CSEIRVDENH KVLLIGDLTI NEGEWISMNG STGEVILGKQ
601: ALAPPALSPD LETFMSWADA IRRLKVMANA DTPEDAIAAR KNGAQGIGLC RTEHMFFGAD RIKAVRKMIM AVTTEQRKAS LDILLPYQRS DFEGIFRAMD
701: GLPVTIRLLD PPLHEFLPEG DLDNIVHELA EETGVKEDEV LSRIEKLSEV NPMLGFRGCR LGISYPELTE MQARAIFEAA ASMQDQGVTV IPEIMVPLVG
801: TPQELGHQVD VIRKVAKKVF AEKGHTVSYK VGTMIEIPRA ALIADEIAKE AEFFSFGTND LTQMTFGYSR DDVGKFLPIY LAKGILQHDP FEVLDQQGVG
901: QLIKMATEKG RAARPSLKVG ICGEHGGDPS SVGFFAEAGL DYVSCSPFRV PIARLAAAQV VVA
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)