AT4G02070.2
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:plastid 1.000 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : MUTS homolog 6 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
encodes a DNA mismatch repair homolog of human MutS gene, MSH6. There are four MutS genes in Arabidopsis, MSH2, MSH3, MSH6, and MSH7, which all act as heterodimers and bind to 51-mer duplexes. MSH2*MSH6 bound the (+T) substrate strongly, (T/G) well, and (+AAG) no better than it did a (T/A) homoduplex. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
MUTS homolog 6 (MSH6); FUNCTIONS IN: damaged DNA binding; INVOLVED IN: mismatch repair; LOCATED IN: chloroplast; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: DNA mismatch repair protein Msh6 (InterPro:IPR017261), DNA mismatch repair protein MutS, clamp (InterPro:IPR007861), DNA mismatch repair protein MutS, connector (InterPro:IPR007860), DNA mismatch repair protein MutS, core (InterPro:IPR007696), DNA mismatch repair protein MutS-like, N-terminal (InterPro:IPR007695), DNA mismatch repair protein MutS, N-terminal (InterPro:IPR016151), DNA mismatch repair protein MutS, C-terminal (InterPro:IPR000432), DNA mismatch repair protein MutS-homologue MSH6 (InterPro:IPR015536), Tudor domain (InterPro:IPR002999); BEST Arabidopsis thaliana protein match is: homolog of DNA mismatch repair protein MSH3 (TAIR:AT4G25540.1). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr4:+:906079..912930 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 146378.00 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 6.56 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.49 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 1321 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
0001: MAPSRRQISG RSPLVNQQRQ ITSFFGKSAS SSSSPSPSPS PSLSNKKTPK SNNPNPKSPS PSPSPPKKTP KLNPNPSSNL PARSPSPGPD TPSPVQSKFK 0101: KPLLVIGQTP SPPQSVVITY GDEVVGKQVR VYWPLDKKWY DGSVTFYDKG EGKHVVEYED GEEESLDLGK EKTEWVVGEK SGDRFNRLKR GASALRKVVT 0201: DSDDDVEMGN VEEDKSDGDD SSDEDWGKNV GKEVCESEED DVELVDENEM DEEELVEEKD EETSKVNRVS KTDSRKRKTS EVTKSGGEKK SKTDTGTILK 0301: GFKASVVEPA KKIGQADRVV KGLEDNVLDG DALARFGARD SEKFRFLGVD AKRRRPTDEN YDPRTLYLPP DFVKKLTGGQ RQWWEFKAKH MDKVVFFKMG 0401: KFYELFEMDA HVGAKELDIQ YMKGEQPHCG FPEKNFSVNI EKLVRKGYRV LVVEQTETPD QLEQRRKETG SKDKVVKREV CAVVTKGTLT DGEMLLTNPD 0501: ASYLMALTEG GESLTNPTAE HNFGVCLVDV ATQKIILGQF KDDQDCSALS CLLSEMRPVE IIKPAKVLSY ATERTIVRQT RNPLVNNLVP LSEFWDSEKT 0601: IYEVGIIYKR INCQPSSAYS SEGKILGDGS SFLPKMLSEL ATEDKNGSLA LSALGGAIYY LRQAFLDESL LRFAKFESLP YCDFSNVNEK QHMVLDAAAL 0701: ENLEIFENSR NGGYSGTLYA QLNQCITASG KRLLKTWLAR PLYNTELIKE RQDAVAILRG ENLPYSLEFR KSLSRLPDME RLIARMFSSI EASGRNGDKV 0801: VLYEDTAKKQ VQEFISTLRG CETMAEACSS LRAILKHDTS RRLLHLLTPG QSLPNISSSI KYFKDAFDWV EAHNSGRVIP HEGADEEYDC ACKTVEEFES 0901: SLKKHLKEQR KLLGDASINY VTVGKDEYLL EVPESLSGSV PHDYELCSSK KGVSRYWTPT IKKLLKELSQ AKSEKESALK SISQRLIGRF CEHQEKWRQL 1001: VSATAELDVL ISLAFASDSY EGVRCRPVIS GSTSDGVPHL SATGLGHPVL RGDSLGRGSF VPNNVKIGGA EKASFILLTG PNMGGKSTLL RQVCLAVILA 1101: QIGADVPAET FEVSPVDKIC VRMGAKDHIM AGQSTFLTEL SETAVMLTSA TRNSLVVLDE LGRGTATSDG QAIAESVLEH FIEKVQCRGF FSTHYHRLSV 1201: DYQTNPKVSL CHMACQIGEG IGGVEEVTFL YRLTPGACPK SYGVNVARLA GLPDYVLQRA VIKSQEFEAL YGKNHRKTDH KLAAMIKQII SSVASDSDYS 1301: ASKDSLCELH SMANTFLRLT N |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)