AT3G07610.3
|
Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:nucleus 1.000 What is SUBAcon? |
|||||||||||||||||||||||||||||||||
| Experimental Localisations and PPI |
|
||||||||||||||||||||||||||||||||
|
SUBAcon links
AGI-AGI relationships |
|
||||||||||||||||||||||||||||||||
| Description (TAIR10) | protein_coding : Transcription factor jumonji (jmjC) domain-containing protein | ||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
IBM1 likely encodes a protein with histone H3mK9 demethylation activity. It may preferentially demethylate H3mK9 at low-copy loci to protect them from silencing by nearby heterochromatin by preventing the spread of cytosine methylation. BONSAI (At1g73177) is hypermethylated in ibm1 mutants. ibm1 mutants have morphological defects that become apparent at the F3 generation, including small narrow leaves, arrested flower development, and faulty pollen development. These phenotypes cannot result solely from the BONSAI hypermethylation. Aberrant phenotypes in ibm1 mutants in both DNA methylation and plant development can be suppressed by mutations in the KYP H3K9 methyltransferase or he CMT3 non CG-cytosine methylase. | ||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
increase in bonsai methylation 1 (IBM1); FUNCTIONS IN: sequence-specific DNA binding transcription factor activity, histone demethylase activity (H3-K9 specific); INVOLVED IN: flower development, DNA methylation on cytosine, leaf development, pollen development, histone H3-K9 demethylation; LOCATED IN: cellular_component unknown; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Transcription factor jumonji/aspartyl beta-hydroxylase (InterPro:IPR003347), Transcription factor jumonji (InterPro:IPR013129); BEST Arabidopsis thaliana protein match is: Transcription factor jumonji (jmjC) domain-containing protein (TAIR:AT1G11950.1). | ||||||||||||||||||||||||||||||||
| Protein Annotations |
|
||||||||||||||||||||||||||||||||
| Coordinates (TAIR10) | chr3:+:2426148..2432876 | ||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 118893.00 Da | ||||||||||||||||||||||||||||||||
| IEP (calculated) | 7.97 | ||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.73 | ||||||||||||||||||||||||||||||||
| Length | 1049 amino acids | ||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
0001: MDSVEEEGVV RVEEENGRGG LRRHRRVSTK LANYVDPPTD DEEDGGPKRK GKRGGNRAPK KTPKKDEEMQ KNEIDEANRV TGLVKEKRAA TKILNRKDSI 0101: IEVGEASGSM PKEVKGIRIG KRKGEIDGEI PTKPGKKPKT TVDPRIIGYR PDNMCHQCQK SDRIVERCQT CNSKRYCHPC LDTWYPLIAK EDVAKKCMFC 0201: SSTCNCRACL RLDTKLKGIN SNLIVSEEEK VQASKFILQS LLPHLKGIND EQVAEKEVEA KIYGLKFEEV RPQDAKAFPD ERLYCDICKT SIYDLHRNCK 0301: SCSFDICLSC CLEIRNGKAL ACKEDVSWNY INRGLEYEHG QEGKVIEKPA NKLDDKLKDK LDGKPDDKPK GKPKGRPKGK PDDKPKGKLK GKQDDKPDDK 0401: PDEKPVNTDH MKYPSLWKAN EAGIITCCCG AGELVLKRLL PDGWISELVN RVEKTAEAGE LLNLPETVLE RCPCSNSDRH IDIDSCNLLK AACREGSEDN 0501: YLYSPSVWDV QQDDLKHFQH HWVKGEPVIV RNVLEATSGL SWEPMVMHRA CRQISHVQHG SLKDVVAVDC LDFCEVKVNL HEFFTGYTDG RYDRMGWPLV 0601: LKLKDWPPAK VFKDNLPRHA EEFLCSLPLK HYTHPVNGPL NLAVKLPQNC LKPDMGPKTY VASGFAQELG RGDSVTKLHC DMSDADLWTK LYPFNVSPSI 0701: AFLVLHRPGI RFLVLLMPNM QPGIGNLKKK HAEQDLKELY SSVANKEEMM EILENSRQQV QNVETDDGAL WDIFRREDIP KLESYIEKHH KEFRHLYCCP 0801: VSQVVHPIHD QNFYLTRYHI MKLKEEYGIE PWTFNQKLGD AVLIPVGCPH QVRNLKSCNK VALDFVSPEN VSECLRLTKQ YRLLPPNHFA KEDKLGVKKM 0901: IVHAVDKALR DLSGEKSPEP EEKKQNMRGP KKGAAKAVAK ALKDLSPSEK KSSEAAEEEI SNGIVNAIDK GLKDLPPSEE KSSEAKVEIS NGIVSAMDKD 1001: LEHISSSEKK STEEEGVKRP NIVRTYERRK KLGSEVTNAY IDRLEMEKM |
||||||||||||||||||||||||||||||||
| See Also |
|
||||||||||||||||||||||||||||||||
Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)