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AT2G22010.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
nucleus 0.868
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : related to KPC1
Curator
Summary (TAIR10)
Encodes a protein predicted to act as a RING E3 ubiquitin ligase. It appears to regulate the stability of the KRP1/ICK1 cyclin dependent kinase inhibitor. Induced by beet severe curly virus (BSCTV) C4 protein.
Computational
Description (TAIR10)
related to KPC1 (RKP); FUNCTIONS IN: zinc ion binding; INVOLVED IN: regulation of cell cycle, response to virus, proteolysis involved in cellular protein catabolic process; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type (InterPro:IPR001841), SPla/RYanodine receptor subgroup (InterPro:IPR018355), B302 (SPRY)-like (InterPro:IPR001870), SPla/RYanodine receptor SPRY (InterPro:IPR003877); Has 1690 Blast hits to 1529 proteins in 192 species: Archae - 0; Bacteria - 13; Metazoa - 1117; Fungi - 103; Plants - 141; Viruses - 2; Other Eukaryotes - 314 (source: NCBI BLink).
Protein Annotations
BioGrid:2090EC:6.3.2.-eggNOG:ENOG410XQ4VeggNOG:KOG2242
eggNOG:KOG4692EMBL:AC007019EMBL:AK230019EMBL:CP002685
EnsemblPlants:AT2G22010EnsemblPlants:AT2G22010.1entrez:816737ExpressionAtlas:Q9SIZ8
Gene3D:3.30.40.10GeneID:816737Genevisible:Q9SIZ8GO:GO:0000151
GO:GO:0004842GO:GO:0006511GO:GO:0008270GO:GO:0016021
GO:GO:0016567GO:GO:0016874GO:GO:0030163GO:GO:0034450
GO:GO:0060154hmmpanther:PTHR13363hmmpanther:PTHR13363:SF1HOGENOM:HOG000029423
InParanoid:Q9SIZ8InterPro:IPR001841InterPro:IPR001870InterPro:IPR003877
InterPro:IPR013083InterPro:IPR013320InterPro:IPR019474iPTMnet:Q9SIZ8
PaxDb:Q9SIZ8Pfam:PF00622Pfam:PF10408Pfam:PF13920
Pfam:Q9SIZ8Pfscan:PS50089Pfscan:PS50188PIR:H84607
PRIDE:Q9SIZ8PRO:PR:Q9SIZ8PROSITE:PS50089PROSITE:PS50188
ProteinModelPortal:Q9SIZ8Proteomes:UP000006548RefSeq:NP_850020.1SMART:SM00449
SMR:Q9SIZ8STRING:3702.AT2G22010.2SUPFAM:SSF49899SUPFAM:SSF57850
TAIR:AT2G22010tair10-symbols:RKPUniGene:At.39495UniProt:Q9SIZ8
Coordinates (TAIR10) chr2:-:9363946..9368828
Molecular Weight (calculated) 144507.00 Da
IEP (calculated) 5.27
GRAVY (calculated) -0.17
Length 1280 amino acids
Sequence (TAIR10)
(BLAST)
0001: MAEDSLRVGM ISSGLAVLLN GEDAKENSSK ARIVPHFDYS GHRPLERTIE FIFGLAEKSV GPLDGQVDSS LIRAVIKNQF SKLHGDLDVS VSQREGISVV
0101: HHGVGPPIVG LEEFSICGDI RIVKPPLVLE SLALFSSARA NACIWKGKWM YEVALETSGI QQLGWATLAC PFTDQKGVGD ADDSYAFDGR RVSKWNKEAE
0201: PYGQSWVAGD VIGCCIDLNC DEIYFYRNGV SLGAAFTGIR KLGPGFGYYP AISLSQGERC ELNFGAYPFK YPVDGFQPLQ EAPTRFSFAT ELLRCFSRLL
0301: DRPDRSLADT LSRLRRFASV EELFCPVSSA ICDEFFYILE QDPLLAEYLG RGAFLSFLLE TFRTQAPHDS SSLDKVLDVF LEFPQSHLIF EHVVNALACG
0401: CKTATLILTE CPYSGPYPYL ALACHLFKRE ELMVQWWRSL HFEFLFEGFL SCRSSNKHDL QHLMPVVWWP GSSEDISYES SMGFTISALS EAINKIEEKQ
0501: RNLCLLVIQF IPPVSPPQLP GSAFRGFLQN LLLKNRGADR TLAPSGVTRN SVLVSLFSVI LHFLSEGFAM LKSSEAVHHN VGFLHRGGQQ KFPLSLFLKN
0601: DPHRADITRL GGLFSHISKS YPTDDQEEEI MRWEEGCMDD EQNRVTHATE QKPCCCLAYD TDLTKSLKDR GKNTAQSSRG RCSSIPERSS HVAAECSAGS
0701: FSEEIDDKPS TSNQSDPDFG YRPVRFMRTA LQESRISSAI LSEEELLDAL LLLYHIAVAP NFKQASYYMS HQSQSISLLE ETDKQIRERA SCDQIKRLKE
0801: ARNNYKEDVM DCVRHSAWFR ISLFSRWKQR GMYALCMWVV QLLLVLSKMD SVFVYIPEFY LESLVDCFHV LRKSDPPFVP STTFIKQGLS SFITFVVTHF
0901: NDSRISNTDL KDLLLQSISV LVQYKEYLEA FENNEAATRH MPAALLAAFD NRSWIPVTNI FLRLCKGSGF SSLKNGESSF SSTVFQALLR DACINDGELL
1001: STFLNRLFNT LSWTITEFSV SVREMQEKYQ VMEFQQRKCC VIFELSSNLA RVLEFCTYAM PQAFLAGTDT NLRRLTELIL FILNHMTSAV DDEFFDLSLR
1101: RQGQPSEKVS RGILLAPLVG IILNLLEASE DSKPKQQHDV IGLFASMDCP DTVYYGFQYL LEYNWDGCVS GDDAYVKKLG QLENFLSHLI NRASSQEPER
1201: KEESFNKDTT DIEDNTCCIC YAGEANAMIA PCSHRSCYGC ITRHLLNCQR CFFCNATVID VIRDKEEEEE EDDDGHKRST
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)