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AT5G28840.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
cytosol 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31615849 (2019): plastid plastid thylakoid
  • PMID:31520498 (2020): mitochondrion
  • PMID:31186290 (2019): cytosol None
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:29104584 (2017): nucleus nuclear matrix nucleolus
  • PMID:26781341 (2016): plasma membrane
  • PMID:25641898 (2015): plasma membrane
  • PMID:24361574 (2014): plastid plastid stroma
  • PMID:24124904 (2013): plastid
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:21988472 (2012): plant-type vacuole plant-type vacuole membrane
  • PMID:21166475 (2011): cytosol
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : GDP-D-mannose 3',5'-epimerase
Curator
Summary (TAIR10)
Encodes a protein with GDP-D-mannose 3',5'-epimerase activity. The enzyme is involved in ascorbate biosynthesis. It catalyzes the conversion of GDP-D-mannose to GDP-L-galactose.
Computational
Description (TAIR10)
GDP-D-mannose 3',5'-epimerase (GME); FUNCTIONS IN: NAD or NADH binding, GDP-mannose 3,5-epimerase activity, catalytic activity; INVOLVED IN: L-ascorbic acid biosynthetic process, nucleotide-sugar metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 17 growth stages; CONTAINS InterPro DOMAIN/s: NAD-dependent epimerase/dehydratase (InterPro:IPR001509), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: NAD(P)-binding Rossmann-fold superfamily protein (TAIR:AT3G62830.2); Has 30173 Blast hits to 30172 proteins in 2803 species: Archae - 688; Bacteria - 17773; Metazoa - 351; Fungi - 177; Plants - 999; Viruses - 17; Other Eukaryotes - 10168 (source: NCBI BLink).
Protein Annotations
eggNOG:COG0451eggNOG:KOG1429EMBL:AK226220EnsemblPlants:AT5G28840
EnsemblPlants:AT5G28840.1EnsemblPlants:AT5G28840.2entrez:833002ExpressionAtlas:Q0WWW3
Gene3D:3.40.50.720GeneID:833002GO:GO:0003824GO:GO:0050662
Gramene:AT5G28840.1Gramene:AT5G28840.2hmmpanther:PTHR10366hmmpanther:PTHR10366:SF327
InterPro:IPR001509InterPro:IPR016040iPTMnet:Q0WWW3KEGG:ath:AT5G28840
KO:K10046OMA:GGFIGHHPaxDb:Q0WWW3Pfam:PF01370
Pfam:Q93VR3PhylomeDB:Q0WWW3PRIDE:Q0WWW3ProteinModelPortal:Q0WWW3
RefSeq:NP_001190417.1RefSeq:NP_198236.1SMR:Q0WWW3STRING:3702.AT5G28840.1
SUPFAM:SSF51735TAIR:AT5G28840tair10-symbols:GMEUniGene:At.21733
UniProt:Q0WWW3UniProt:Q93VR3
Coordinates (TAIR10) chr5:-:10862472..10864024
Molecular Weight (calculated) 42760.80 Da
IEP (calculated) 6.15
GRAVY (calculated) -0.49
Length 377 amino acids
Sequence (TAIR10)
(BLAST)
001: MGTTNGTDYG AYTYKELERE QYWPSENLKI SITGAGGFIA SHIARRLKHE GHYVIASDWK KNEHMTEDMF CDEFHLVDLR VMENCLKVTE GVDHVFNLAA
101: DMGGMGFIQS NHSVIMYNNT MISFNMIEAA RINGIKRFFY ASSACIYPEF KQLETTNVSL KESDAWPAEP QDAYGLEKLA TEELCKHYNK DFGIECRIGR
201: FHNIYGPFGT WKGGREKAPA AFCRKAQTST DRFEMWGDGL QTRSFTFIDE CVEGVLRLTK SDFREPVNIG SDEMVSMNEM AEMVLSFEEK KLPIHHIPGP
301: EGVRGRNSDN NLIKEKLGWA PNMRLKEGLR ITYFWIKEQI EKEKAKGSDV SLYGSSKVVG TQAPVQLGSL RAADGKE
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)