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AT4G30870.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : Restriction endonuclease, type II-like superfamily protein
Curator
Summary (TAIR10)
Encodes an Arabidopsis homolog of the endonuclease MSU81. T-DNA insertion lines of AtMSU81 have a deficiency in homologous recombination in somatic cells but only after genotoxic stress. Crosses with a hyperrecombinogenic mutant of the AtRecQ4A helicase resulted in synthetic lethality in the double mutant.
Computational
Description (TAIR10)
MMS AND UV SENSITIVE 81 (MUS81); CONTAINS InterPro DOMAIN/s: ERCC4 domain (InterPro:IPR006166), Helix-hairpin-helix DNA-binding motif, class 1 (InterPro:IPR003583), Restriction endonuclease, type II-like (InterPro:IPR011335); BEST Arabidopsis thaliana protein match is: Restriction endonuclease, type II-like superfamily protein (TAIR:AT5G39770.1); Has 631 Blast hits to 481 proteins in 192 species: Archae - 11; Bacteria - 4; Metazoa - 158; Fungi - 249; Plants - 48; Viruses - 0; Other Eukaryotes - 161 (source: NCBI BLink).
Protein Annotations
EC:3.1.22.-eggNOG:COG1948eggNOG:KOG2379EMBL:AB177892
EMBL:AL022198EMBL:AL161577EMBL:CP002687EMBL:EF154086
EnsemblPlants:AT4G30870EnsemblPlants:AT4G30870.1entrez:829211Gene3D:3.40.50.10130
GeneID:829211GO:GO:0000724GO:GO:0000794GO:GO:0003677
GO:GO:0004519GO:GO:0005730GO:GO:0006281GO:GO:0006312
GO:GO:0006974GO:GO:0007067GO:GO:0046872GO:GO:0051026
GO:GO:0051301Gramene:AT4G30870.1hmmpanther:PTHR13451hmmpanther:PTHR13451:SF0
HOGENOM:HOG000029569InParanoid:Q5W9E7InterPro:IPR006166InterPro:IPR011335
InterPro:IPR020819InterPro:IPR033309KEGG:ath:AT4G30870KO:K08991
OMA:RTADNCAPANTHER:PTHR13451:SF0PaxDb:Q5W9E7Pfam:PF02732
Pfam:Q5W9E7PhylomeDB:Q5W9E7PIR:D85361PRIDE:Q5W9E7
PRO:PR:Q5W9E7ProteinModelPortal:Q5W9E7Proteomes:UP000006548RefSeq:NP_194816.2
SMART:SM00891SMR:Q5W9E7STRING:3702.AT4G30870.1SUPFAM:SSF52980
TAIR:AT4G30870tair10-symbols:ATMUS81tair10-symbols:MUS81UniGene:At.51242
UniProt:Q5W9E7
Coordinates (TAIR10) chr4:+:15028586..15032461
Molecular Weight (calculated) 74060.00 Da
IEP (calculated) 8.27
GRAVY (calculated) -0.55
Length 659 amino acids
Sequence (TAIR10)
(BLAST)
001: MDDERRVLCP ENRGLAAYVL QKKQEYAEKP KGLSENLERT FVKGYRSVCD AKDPINTLKD LSQIKGFGKW MVKLMKGYFD TAVESSEQED LPDNRAGKKA
101: NGKKRYIPQR NSVGYALLIT LHRRTTNGKE FMRKQELIDA ADANGLSHAP VGPEKGKGKA GLGHSKREWY SGWSCMTTLI QKGLVVKSSN PAKYMLTVEG
201: REVANECILR SGLPDSVDIL SVDEMDPTPQ AKKTPNQNPT CSFTMREELP YVDPRCRAQS AIPSDILEKF TPFGYSKEQV VAAFREVSDG SGDKDPSTLW
301: LSVMCHLRQA EVYNSCPDSR NSKKDSSGPF KSQIRQVDLE GSRAKKFRSC NDGSTLNPCS SGSSHAVKAC SSSLASDGTK GITNIPRLPP LQFGETFEEA
401: YDVILILDDR EKFATKGSRS RNIVENICSE FNIKIEVRRL PVGDCIWIAR HKYLETEYVL DFIAERKNVD DMRSSIRDNR YRDQKLRLQR SGFKKLIYIL
501: EGDPNHSDAA ESIKTACFTT EILEGFDVLR THGLGETLRK YGYLTKSIYQ YYKLRVNDND QSKGAASCPS FDSFVKRCQD LDKMTISDVF AIQLMQVPQV
601: TEEIAIAVLD MYPTLLSLAS AYSHLEADVS AQEEMLRNRS NNVICASASK NIFKLVWGE
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)