AT4G02600.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:plasma membrane 1.000 ASURE: plasma membrane What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : Seven transmembrane MLO family protein | ||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO1 belongs to the clade II, with ATMLO13 and ATMLO15. The gene is expressed during early seedling growth, in root and cotyledon vascular system, in pollen and in papillae, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s). | ||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
MLO1; FUNCTIONS IN: calmodulin binding; INVOLVED IN: cell death, defense response; LOCATED IN: plasma membrane; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Mlo-related protein (InterPro:IPR004326); BEST Arabidopsis thaliana protein match is: Seven transmembrane MLO family protein (TAIR:AT2G44110.1); Has 552 Blast hits to 532 proteins in 57 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 548; Viruses - 0; Other Eukaryotes - 4 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr4:+:1144141..1147156 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 59129.20 Da | ||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 8.69 | ||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | 0.19 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 526 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MGHGGEGMSL EFTPTWVVAG VCTVIVAISL AVERLLHYFG TVLKKKKQKP LYEALQKVKE ELMLLGFISL LLTVFQGLIS KFCVKENVLM HMLPCSLDSR 101: REAGASEHKN VTAKEHFQTF LPIVGTTRRL LAEHAAVQVG YCSEKGKVPL LSLEALHHLH IFIFVLAISH VTFCVLTVIF GSTRIHQWKK WEDSIADEKF 201: DPETALRKRR VTHVHNHAFI KEHFLGIGKD SVILGWTQSF LKQFYDSVTK SDYVTLRLGF IMTHCKGNPK LNFHKYMMRA LEDDFKQVVG ISWYLWIFVV 301: IFLLLNVNGW HTYFWIAFIP FALLLAVGTK LEHVIAQLAH EVAEKHVAIE GDLVVKPSDE HFWFSKPQIV LYLIHFILFQ NAFEIAFFFW IWVTYGFDSC 401: IMGQVRYIVP RLVIGVFIQV LCSYSTLPLY AIVSQMGSSF KKAIFEENVQ VGLVGWAQKV KQKRDLKAAA SNGDEGSSQA GPGPDSGSGS APAAGPGAGF 501: AGIQLSRVTR NNAGDTNNEI TPDHNN |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)