AT2G17480.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:plasma membrane 1.000 ASURE: plasma membrane What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : Seven transmembrane MLO family protein | ||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO8 belongs to the clade III, with AtMLO5, AtMLO7, AtMLO9, and AtMLO10. The gene is expressed during seedling growth, in cotyledons and hypocotyl, and in fruit abscission zone, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s). | ||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
MILDEW RESISTANCE LOCUS O 8 (MLO8); FUNCTIONS IN: calmodulin binding; INVOLVED IN: cell death, defense response; LOCATED IN: plasma membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Mlo-related protein (InterPro:IPR004326); BEST Arabidopsis thaliana protein match is: Seven transmembrane MLO family protein (TAIR:AT5G65970.1); Has 544 Blast hits to 526 proteins in 58 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 539; Viruses - 0; Other Eukaryotes - 5 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr2:-:7590559..7593768 | ||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 67216.00 Da | ||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 9.52 | ||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | 0.04 | ||||||||||||||||||||||||||||||||||||||||||||
| Length | 593 amino acids | ||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MGIIDGSLLR RLICLCLWCL LGGGVTVVTA EDEKKVVHKQ LNQTPTWAVA AVCTFFIVVS VLLEKLLHKV GKVLWDRHKT ALLDALEKIK AELMVLGFIS 101: LLLTFGQTYI LDICIPSHVA RTMLPCPAPN LKKEDDDNGE SHRRLLSFEH RFLSGGEASP TKCTKEGYVE LISAEALHQL HILIFFLAIF HVLYSFLTMM 201: LGRLKIRGWK HWENETSSHN YEFSTDTSRF RLTHETSFVR AHTSFWTRIP FFFYVGCFFR QFFRSVGRTD YLTLRNGFIA VHLAPGSQFN FQKYIKRSLE 301: DDFKVVVGVS PVLWGSFVLF LLLNIDGFKM MFIGTAIPVI IILAVGTKLQ AIMTRMALGI TDRHAVVQGM PLVQGNDEYF WFGRPHLILH LMHFALFQNA 401: FQITYFFWIW YSFGSDSCYH PNFKIALVKV AIALGVLCLC SYITLPLYAL VTQMGSRMKK SVFDEQTSKA LKKWRMAVKK KKGVKATTKR LGGDGSASPT 501: ASTVRSTSSV RSLQRYKTTP HSMRYEGLDP ETSDLDTDNE ALTPPKSPPS FELVVKVEPN KTNTGETSRD TETDSKEFSF VKPAPSNESS QDR |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)