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AT3G19050.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
nucleus 0.832
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : phragmoplast orienting kinesin 2
Curator
Summary (TAIR10)
PHRAGMOPLAST ORIENTING KINESIN 2 is one of the two Arabidopsis homologs isolated in yeast two-hybrid screen for interaction partners of maize gene TANGLED1 (TAN1). Based on sequence homology in their motor domains, POK1 and POK2 belong to the kinesin-12 class which also includes the well-characterized group of phragmoplast-associated kinesins AtPAKRPs. Both kinesins are composed of an N-terminal motor domain throughout the entire C terminus and putative cargo binding tail domains. The expression domains for POK2 constructs were broader than those for POK1; both are expressed in tissues enriched for dividing cells. The phenotype of pok1/pok2 double mutants strongly resembles that of maize tan1 mutants, characterized by misoriented mitotic cytoskeletal arrays and misplaced cell walls.
Computational
Description (TAIR10)
phragmoplast orienting kinesin 2 (POK2); FUNCTIONS IN: microtubule motor activity, ATP binding; INVOLVED IN: cytokinesis; EXPRESSED IN: root vascular system, primary root tip, lateral root primordium; CONTAINS InterPro DOMAIN/s: Kinesin, motor region, conserved site (InterPro:IPR019821), Kinesin, motor domain (InterPro:IPR001752); BEST Arabidopsis thaliana protein match is: phragmoplast orienting kinesin 1 (TAIR:AT3G17360.1); Has 204267 Blast hits to 80386 proteins in 3219 species: Archae - 3327; Bacteria - 35963; Metazoa - 90351; Fungi - 17822; Plants - 12667; Viruses - 746; Other Eukaryotes - 43391 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:GQT-1917-MONOMERBioGrid:6772eggNOG:COG5059eggNOG:KOG4280
EMBL:AP000735EMBL:CP002686EMBL:DQ399530EnsemblPlants:AT3G19050
EnsemblPlants:AT3G19050.1entrez:821439Gene3D:3.40.850.10GeneID:821439
Genevisible:Q27IK6GO:GO:0000281GO:GO:0000911GO:GO:0003777
GO:GO:0005524GO:GO:0005871GO:GO:0005874GO:GO:0007018
GO:GO:0009524GO:GO:0016887Gramene:AT3G19050.1hmmpanther:PTHR24115
hmmpanther:PTHR24115:SF506HOGENOM:HOG000084308InParanoid:Q27IK6InterPro:IPR001752
InterPro:IPR019821InterPro:IPR024658InterPro:IPR027417InterPro:IPR027640
iPTMnet:Q27IK6KEGG:ath:AT3G19050KO:K10400ncoils:Coil
OMA:TRIDSENPANTHER:PTHR24115PaxDb:Q27IK6Pfam:PF00225
Pfam:PF12711Pfam:Q27IK6Pfscan:PS50067PhylomeDB:Q27IK6
PRIDE:Q27IK6PRINTS:PR00380PRO:PR:Q27IK6PROSITE:PS00411
PROSITE:PS50067ProteinModelPortal:Q27IK6Proteomes:UP000006548RefSeq:NP_188535.4
scanprosite:PS00411SMART:SM00129STRING:3702.AT3G19050.1SUPFAM:SSF52540
TAIR:AT3G19050tair10-symbols:POK2UniGene:At.53380UniProt:Q27IK6
Coordinates (TAIR10) chr3:+:6578047..6590106
Molecular Weight (calculated) 315080.00 Da
IEP (calculated) 4.86
GRAVY (calculated) -0.59
Length 2771 amino acids
Sequence (TAIR10)
(BLAST)
0001: MSKETKLSRR DSDNHDDEIE NVPENLRASL LSLTSNDSLK NPKHECGSKI DRTPSKPRAK NPDPALPLRT PDKYRSAAAF SKNRFGWGDK CDSITNTTNA
0101: ALLNTTPKTG RVVGRAYSET NSTQNTPTKS VSKPPGSCYR GKLDGTGTVR AGGYASLYKG LSSSSGQVST VVNSVEVPHF SLKEDPSFWM DHNVQILIRV
0201: RPLNSMERSI NGYNRCLKQE SSQCVAWIGP PETRFQFDHV ACETIDQETL FRVAGLPMVE NCLSGYNSCI FAYGQTGSGK TYTMLGEVGD LEFKPSPNRG
0301: MMPRIFEFLF ARIQAEEESR RDERLKYNCK CSFLEIYNEQ ITDLLEPSST NLQLREDIKS GVYVENLTEC EVQSVQDILG LITQGSLNRR VGATNMNRES
0401: SRSHSVFTCV IESRWEKDST ANMRFARLNL VDLAGSERQK TSGAEGDRLK EAASINKSLS TLGHVIMVLV DVANGKPRHI PYRDSRLTFL LQDSLGGNSK
0501: TMIIANASPS VSCAAETLNT LKFAQRAKLI QNNAVVNEDS NEDVLELRRQ IRLLKEELSL LKRQNISRAL SFGSATANFA ESQVDSPSSV MHETGQQQAG
0601: NLLVYESGGC VRMSRKQLKS LEITLAGSLR REHVADASIK KLEAEIEHLN RLVRQREEDT RSTKMMLRFR EDKIQRLESL LGNHISADSF LLEENNVLSE
0701: EIQLLQAKID KNPELTRFAL ENIRLLDQLR RFQEFYEEGE REILLGEVSN LRNQLFQFLD ENSDWQKHVD DGIEPQGASR MSKENCSLQE ELKKTCYELE
0801: KCRSNLGSCL EENAKLSREI NDLQAMVSDI RACTPDEHSS VNKQKALLGT QNFEPHETLA CEQANYVEEI IKLQLDLDVQ KIILDEERTL RGDTEAQAVR
0901: LKFDIEVLKD QLLLISKQQK NVYSELGETK SAVAALESQN IILIQEAVEL RRIKENYFEL LKKQELDIPA MKSKQCDEFK DNPAEDSEID TKFKKMQASL
1001: EKAKRLNMLY KSDIASKACG DEEMDEVCKQ AEAATAEVIV CLQNELEVLQ KEVNDFQSKE NVTEKQVEIL ETQMEELQDK LRDTTMDNEQ LQEQLRGKDM
1101: ELLIISNEME LLTSELEEIL LNGNEGLTDA CYQADLISGS LPDKRIWISE QVGGLIRTLS ERELMIEDLE SCLEDANKKR CDIESMLKSL KGAAIVMNEA
1201: HQREFEEKET DVLLLKSQLC TKTETILRLQ EKLKMAERLI YEASDCATAS LIIVNRYSEV TESHTFELKQ KDFQVAESTG TILSLKQQVQ DLEATCKEFR
1301: SKLLEEEKNA SAMEQKLEEI EETSISAMKE KLSELKGGVS DLRSCITMCQ EHDKYTEAEN SLSSPAHCSE GQEPGRNVVV SSCIEKTPNN NHTESMRLSS
1401: KVSSERGKVI ILLKQEMESA LASLKEVQVE MANLKGEKEE LKASEKRSLS NLNDLAAQIC NLNTVMSNME EQYEHKMEVT DHKLKTLEHE IAKMKIEADQ
1501: EYVENLCILK KFEEAQGTIR EADITVNELV IANEKMRFDL EKQKKRGISL VGEKKALVEK LQELESINVK ENEKLAYLEK LFESSLMGIG NLVEELATVV
1601: RKLQDESSVA LTGMAKDLSE LKSWVSETNS ARLFLEDIWS EIIMKDCAIS VLHLCHMGIL LETVTGINTE NGLLQRGLCV SNSSIAGLRD NNLRLRRELE
1701: MFANLKGKLL TDIKNGFERI SRNEEATNLL TTKLSSFDQK ISGLQYQEDL MLQRSNSMGS QLDILLKEID LSNGDLAETL LEQERHLNQK NDFFDTEVQL
1801: YLMDLCSKDV ELLVLAQTAK EYSSCLAVVD RELLDHHVIV EDLKEKLIVS QVEGELKDQC LVDNKLETVS VKEELTEAQS KIKVLSSDLD RSVQKIAEID
1901: EVNKDFGERV IFLESSITGL QQELAMKASE LYSLEHSRSV TAEELDIKER DVQVYADIVS SLKKENVSLK NKFIHFGEDQ FKALDVTRLS IAKCSHLTED
2001: SKKLEKLTRD GMAISDKMLQ LICENVDKAS VFADTVQSLQ IDVQELLSEN LNLHDELLRK DDVLKGLSFD LSLLQESASN SRDKKDETKE IMVHVEALEK
2101: TLALKTFELE DAVSHAQMLE VRLQESKEIT RNLEVDTEKA RKCQEKLSAE NKDIRAEAED LLAEKCSLEE EMIQTKKVSE SMEMELFNLR NALGQLNDTV
2201: AFTQRKLNDA IDERDNLQDE VLNLKEEFGK MKSEAKEMEA RYIEAQQIAE SRKTYADERE EEVKLLEGSV EELEYTINVL ENKVNVVKDE AERQRLQREE
2301: LEMELHTIRQ QMESARNADE EMKRILDEKH MDLAQAKKHI EALERNTADQ KTEITQLSEH ISELNLHAEA QASEYMHKFK ELEAMAEQVK PEIHVSQAID
2401: SSLSKGSGKP RGSGSPFRCI GLGITQQMRS EKDEELAAAR LRIEELETVV STRQKEIFLL NSKLAKVDSM THDINRVLLG VKQNVTNCAS FLDSQQVLKI
2501: AEMLQHNSSD SRERDLEVSH LKQQLNEYNE KRQGWIEEIE GKQTELVTAQ IKLEEHRQYQ QLLKKENELL KKENFSHKIK VMELEGEVKK LSSHQNPEWR
2601: TRDQARIKEE NNVLKLQLDE LNLKLRRADV SVSRAKEELA FYRASSVKNP HSNFDKTHQL STKLKETEED RMQLAQELLS LCTSILKAAG VTGEDFTDIN
2701: PEVAEEALEQ LKTKLGLLES EVHHFRLKGK AKSRRSRNPE RKMPSMPSPR RSWSQSPRSM SQVPFFSSLD R
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)