AT3G17360.1
Subcellular Consensus
(Prediction and Experimental) min: :max .
SUBAcon:nucleus 0.988 ASURE: cytoskeleton What is SUBAcon? |
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Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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Description (TAIR10) | protein_coding : phragmoplast orienting kinesin 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Curator Summary (TAIR10) |
PHRAGMOPLAST ORIENTING KINESIN 1 is one of the two Arabidopsis homologs isolated in yeast two-hybrid screen for interaction partners of maize gene TANGLED1 (TAN1). Based on sequence homology in their motor domains, POK1 and POK2 belong to the kinesin-12 class which also includes the well-characterized group of phragmoplast-associated kinesins AtPAKRPs. Both kinesins are composed of an N-terminal motor domain throughout the entire C terminus and putative cargo binding tail domains. The expression domains for POK1 constructs were more limited than those for POK2; both are expressed in tissues enriched for dividing cells. The phenotype of pok1/pok2 double mutants strongly resembles that of maize tan1 mutants, characterized by misoriented mitotic cytoskeletal arrays and misplaced cell walls. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Computational Description (TAIR10) |
phragmoplast orienting kinesin 1 (POK1); FUNCTIONS IN: microtubule motor activity, ATP binding; INVOLVED IN: cytokinesis; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Kinesin, motor region, conserved site (InterPro:IPR019821), Kinesin, motor domain (InterPro:IPR001752); BEST Arabidopsis thaliana protein match is: phragmoplast orienting kinesin 2 (TAIR:AT3G19050.1); Has 97051 Blast hits to 52483 proteins in 2606 species: Archae - 1597; Bacteria - 13842; Metazoa - 45578; Fungi - 8395; Plants - 6409; Viruses - 244; Other Eukaryotes - 20986 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Protein Annotations |
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Coordinates (TAIR10) | chr3:+:5936108..5946205 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Weight (calculated) | 233892.00 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
IEP (calculated) | 5.03 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GRAVY (calculated) | -0.61 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Length | 2066 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sequence (TAIR10) (BLAST) |
0001: MSRNVPRIEM PESEENEFAS LSLFSPSRPP LNSIPDPSQI QKANHLPHFD LVQKLEGTRA QHQRTLGPEK KFEVLEGRAG NSSDSNPKIV NRNGKSRSEP 0101: NSAQSTPTRN GARVSLGGGC ATGARFLQSF GGRGRIPRGV SIAESVSFAE TTPHFELNED HSFWKDHNVQ VLIRLRPLGT MERANQGYGK CLKQESPQTL 0201: VWLGHPEARF TFDHVASETI SQEKLFRVAG LPMVENCLSG YNSCVFAYGQ TGSGKTYTMM GEISEAEGSL GEDCGVTARI FEYLFSRIKM EEEERRDENL 0301: KFSCKCSFLE IYNEQITDLL EPSSTNLQLR EDLGKGVYVE NLVEHNVRTV SDVLKLLLQG ATNRKIAATR MNSESSRSHS VFTCTIESLW EKDSLTRSRF 0401: ARLNLVDLAG SERQKSSGAE GDRLKEAANI NKSLSTLGLV IMSLVDLAHG KHRHVPYRDS RLTFLLQDSL GGNSKTMIIA NVSPSLCSTN ETLSTLKFAQ 0501: RAKLIQNNAK VNEDASGDVT ALQQEIRKLK VQLTSLLKNH DSCGALSDCI SSLEESRYSG TCKVAGETRQ DKCHCQVKNM NDNMIGALRR EKIAESALQK 0601: SEAEIERIDC LVRDMEEDAK RIKIMLNLRE EKVGEMEFCT SGSLMTKECL IEENKTLKGE IKLLRDSIDK NPELTRSALE NTKLREQLQR YQKFYEHGER 0701: EALLAEVTGL RDQLLDVLEA KDESFSKHVM KENEMEKEFE DCRNMNSSLI RELDEIQAGL GRYLNFDQIQ SNVVASSTRG AEQAETMPTI SEIQEEVAIS 0801: HSKNYDRGAL VKTDEGIDRS ILQFKLGKLM KDLEEARTLN CKYEKDHKSQ LSQQEDIEVV REQVETETAR TILELQEEVI ALQSEFQRRI CNLTEENQSI 0901: KDTITARESE IRALNQDWEK ATLELTNFIV AGSKSIKNAS TQIESIICSF PQVNAWIGDY VEKAAKNCIK KEETILLLQK SLEDARILVA EMNLKLNSLK 1001: GATIALNEFQ LGGNAATTEE AFNLNNDVDR MSDEVDTLES NFKANQYSIL KTERHAEAAL AVTKWLSDSR DQHQMMEKVQ DQSVKEFGTL SSISASLSAE 1101: GNADISLSRD GHLSDATYPK GDELSTSSSD FSNCRWQHDC ALNVKCQGVS SSESDAQESN NKITSAALIA KNGSAHSVYC GEGRQSVEKP LTIMMGREET 1201: EYKCSKPLSS GVYMGLMQRM DPVRTFFDRF EEVNATMKEA DLTICELVKA NEKSNSVTEM WLQTHEELIS KEKNLMDDLE QVKSILSACE EEKQVLLNQT 1301: HTTLADMENS VSLLEEYFQE MKRGVEETVE ALFSHARLAG KELLQLISNS RPSLEQIASE FMEREFTMYA TYQCHIGKLI DQILDQRKQV ITPNLSGQET 1401: NQSVKINAIG YNAEDEVTKK QSREEIVTGL ENDEVVQSHE SLLYENLYLK KELERKEALF EGLLFDFRLL QESASNKRDI KNEMDELFDA LCKVQLELEL 1501: KASQVHELFV HNENLENCSI DLKTALFTSQ SDLEQAKQRI QILAEQNDEL RALVSDLCKE KAAAEEGLDE QRDLVNRLEK EILHLTTTAE KQLLSAVKSI 1601: KENLKKTSDE KDQIVDEICS LNNKLELAYA IADEKEAIAV EAHQESEASK IYAEQKEEEV KILEISVEEL ERTINILERR VYDMDEEVKR HRTTQDSLET 1701: ELQALRQRLF RFENFTGTMV TTNESTEEYK SHISRSTGLQ GAHSQIQVLQ KEVAEQTKEI KQLKEYISEI LLHSEAQSSA YQEKYKTLEV MIRDFKLEDS 1801: SSSAAETISH KTEKSSTRSR GSSSPFRCIV GLVQQMKLEK DQELTMARVR VEELESLLAV KQKEICTLNT RIAAADSMTH DVIRDLLGVK MDITSYAELI 1901: DQHQVQRVVE KAQQHAEEIL SKEQEVMNLK RHIDYLFKDR ESCMSELNKK DTDVLATQIS LDQLQERVQL LSMQNEMLKN DKSNLLRKLA ELDRTVHNAQ 2001: ASNHRVPQTT KDTASFKLAD TDYTKRLENA QKLLSHANNE LAKYRKTSNN HPSTRTQGQS SGTRYR |
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See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)