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AT3G10660.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
endoplasmic reticulum 1.000
ASURE: endoplasmic reticulum
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : calmodulin-domain protein kinase cdpk isoform 2
Curator
Summary (TAIR10)
predicted to encode calcium-dependent protein kinase and is localized to the ER. Protein is myristoylated in a cell-free extract. Changing the proposed myristoylated site, G residue in the amino terminal, to A prevented the meristoylation . The G to A mutation decreased AtCPK2 membrane association by approximately 50%.
Computational
Description (TAIR10)
calmodulin-domain protein kinase cdpk isoform 2 (CPK2); CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), EF-Hand 1, calcium-binding site (InterPro:IPR018247), Serine/threonine-protein kinase domain (InterPro:IPR002290), Calcium-binding EF-hand (InterPro:IPR002048), EF-hand-like domain (InterPro:IPR011992), EF-hand (InterPro:IPR018248), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), EF-HAND 2 (InterPro:IPR018249), Calcium-dependent protein kinase (InterPro:IPR020642), Calcium/calmodulin-dependent protein kinase-like (InterPro:IPR020636); BEST Arabidopsis thaliana protein match is: calcium dependent protein kinase 1 (TAIR:AT5G04870.1); Has 145304 Blast hits to 132515 proteins in 4265 species: Archae - 224; Bacteria - 17128; Metazoa - 53382; Fungi - 18632; Plants - 28672; Viruses - 609; Other Eukaryotes - 26657 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT3G10660-MONOMERBioGrid:5569EC:2.7.11.1eggNOG:ENOG410XRMJ
eggNOG:KOG0032EMBL:AC011560EMBL:AC013428EMBL:AF286222
EMBL:BT046185EMBL:CP002686EMBL:U31833EnsemblPlants:AT3G10660
EnsemblPlants:AT3G10660.1entrez:820235Gene3D:1.10.238.10GeneID:820235
Genevisible:Q38870GO:GO:0004683GO:GO:0005509GO:GO:0005516
GO:GO:0005524GO:GO:0005789GO:GO:0005886GO:GO:0009738
GO:GO:0009931GO:GO:0018105GO:GO:0035556GO:GO:0046777
Gramene:AT3G10660.1hmmpanther:PTHR24349hmmpanther:PTHR24349:SF161HOGENOM:HOG000233030
InParanoid:Q38870InterPro:IPR000719InterPro:IPR002048InterPro:IPR008271
InterPro:IPR011009InterPro:IPR011992InterPro:IPR017441InterPro:IPR018247
KEGG:ath:AT3G10660KO:K13412OMA:QSPFQPEPaxDb:Q38870
Pfam:PF00069Pfam:PF13499Pfam:Q38870Pfscan:PS50011
Pfscan:PS50222PhylomeDB:Q38870PRIDE:Q38870PRO:PR:Q38870
PROSITE:PS00018PROSITE:PS00107PROSITE:PS00108PROSITE:PS50011
PROSITE:PS50222ProteinModelPortal:Q38870Proteomes:UP000006548RefSeq:NP_187677.1
scanprosite:PS00018scanprosite:PS00107scanprosite:PS00108SMART:SM00054
SMART:SM00220SMR:Q38870STRING:3702.AT3G10660.1SUPFAM:SSF47473
SUPFAM:SSF56112TAIR:AT3G10660tair10-symbols:ATCPK2tair10-symbols:CPK2
UniGene:At.9827UniProt:Q38870
Coordinates (TAIR10) chr3:-:3331599..3334268
Molecular Weight (calculated) 72258.00 Da
IEP (calculated) 5.10
GRAVY (calculated) -0.52
Length 646 amino acids
Sequence (TAIR10)
(BLAST)
001: MGNACVGPNI SGNGFLQTVT AAMWRPRIGA EQASSSSHGN GQVSKEAASE PATDQVQNKP PEPITMPSSK TNPETKLKPD LEIQPEEKKE KVLAEETKQK
101: VVPEESKQEV PPEESKREVV VQPESAKPET KSESKPETTK PETTSETKPE TKAEPQKPKH MRRVSSAGLR TESVLQRKTE NFKEFYSLGR KLGQGQFGTT
201: FLCLEKGTGN EYACKSISKR KLLTDEDVED VRREIQIMHH LAGHPNVISI KGAYEDVVAV HLVMELCSGG ELFDRIIQRG HYTERKAAEL ARTIVGVLEA
301: CHSLGVMHRD LKPENFLFVS REEDSLLKTI DFGLSMFFKP DEVFTDVVGS PYYVAPEVLR KRYGPESDVW SAGVIVYILL SGVPPFWAET EQGIFEQVLH
401: GDLDFSSDPW PSISESAKDL VRKMLVRDPK RRLTAHQVLC HPWVQIDGVA PDKPLDSAVL SRMKQFSAMN KFKKMALRVI AESLSEEEIA GLKQMFKMID
501: ADNSGQITFE ELKAGLKRVG ANLKESEILD LMQAADVDNS GTIDYKEFIA ATLHLNKIER EDHLFAAFSY FDKDESGFIT PDELQQACEE FGVEDARIEE
601: MMRDVDQDKD GRIDYNEFVA MMQKGSIMGG PVKMGLENSI SISLKH
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)