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AT3G05530.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
cytosol 0.500
nucleus 0.500
ASURE: cytosol,nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31615849 (2019): plastid plastid thylakoid
  • PMID:31520498 (2020): mitochondrion
  • PMID:31186290 (2019): cytosol None
  • PMID:30961429 (2019): nucleus
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:26781341 (2016): plasma membrane
  • PMID:25900983 (2015): plant-type vacuole plant-type vacuole membrane
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi Golgi apparatus Golgi membrane
  • PMID:25900983 (2015): Golgi
  • PMID:24134884 (2013): cytoskeleton microtubules
  • PMID:23903016 (2013): plant-type vacuole plant-type vacuole membrane
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:22550958 (2012): plastid
  • PMID:22318864 (2012): plasma membrane
  • PMID:22215637 (2012): plasma membrane
  • PMID:21166475 (2011): cytosol
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : regulatory particle triple-A ATPase 5A
Curator
Summary (TAIR10)
Encodes RPT5a (Regulatory Particle 5a), one of the six AAA-ATPases of the proteasome regulatory particle. Essential for gametophyte development. In Arabidopsis, the RPT5 subunit is encoded by two highly homologous genes, RPT5a and RPT5b. RPT5a and RPT5b show accession-dependent functional redundancy. In Wassilewskija (Ws) accession: mutant alleles of RPT5a displayed 50% pollen lethality, indicating that RPT5a is essential for male gametophyte development. In the Columbia (Col) accession, a rpt5a mutant allele did not display such a phenotype because the RPT5b Col allele complements the rpt5a defect in the male gametophyte, whereas the RPT5b Ws allele does not. Double rpt5a rpt5b mutants in Col background showed a complete male and female gametophyte lethal phenotype.
Computational
Description (TAIR10)
regulatory particle triple-A ATPase 5A (RPT5A); CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, core (InterPro:IPR003959), ATPase, AAA-type, conserved site (InterPro:IPR003960), 26S proteasome subunit P45 (InterPro:IPR005937); BEST Arabidopsis thaliana protein match is: 26S proteasome AAA-ATPase subunit RPT5B (TAIR:AT1G09100.1); Has 33265 Blast hits to 30927 proteins in 3145 species: Archae - 1437; Bacteria - 12044; Metazoa - 4947; Fungi - 3672; Plants - 3322; Viruses - 56; Other Eukaryotes - 7787 (source: NCBI BLink).
Protein Annotations
BioGrid:5053eggNOG:COG1222eggNOG:KOG0652EMBL:AC009606
EMBL:AF081573EMBL:AF123394EMBL:AY062705EMBL:BT000140
EMBL:CP002686EnsemblPlants:AT3G05530EnsemblPlants:AT3G05530.1entrez:819718
Gene3D:3.40.50.300GeneID:819718Genevisible:Q9SEI2GO:GO:0000502
GO:GO:0005524GO:GO:0005634GO:GO:0005737GO:GO:0005829
GO:GO:0009553GO:GO:0009555GO:GO:0010498GO:GO:0017025
GO:GO:0030433GO:GO:0031595GO:GO:0031597GO:GO:0036402
GO:GO:0045899GO:GO:1901800Gramene:AT3G05530.1hmmpanther:PTHR23073
hmmpanther:PTHR23073:SF7HOGENOM:HOG000225143InParanoid:Q9SEI2IntAct:Q9SEI2
InterPro:IPR003593InterPro:IPR003959InterPro:IPR003960InterPro:IPR005937
InterPro:IPR027417iPTMnet:Q9SEI2KEGG:ath:AT3G05530KO:K03065
ncoils:CoilOMA:RISHAIDPaxDb:Q9SEI2Pfam:PF00004
Pfam:Q9SEI2PhylomeDB:Q9SEI2PRIDE:Q9SEI2PRO:PR:Q9SEI2
PROSITE:PS00674ProteinModelPortal:Q9SEI2Proteomes:UP000006548Reactome:R-ATH-1236978
Reactome:R-ATH-174184Reactome:R-ATH-349425Reactome:R-ATH-5632684Reactome:R-ATH-68949
Reactome:R-ATH-69017Reactome:R-ATH-983168RefSeq:NP_187204.1scanprosite:PS00674
SMART:SM00382SMR:Q9SEI2STRING:3702.AT3G05530.1SUPFAM:SSF52540
TAIR:AT3G05530tair10-symbols:ATS6A.2tair10-symbols:RPT5ATIGRfam:TIGR01242
TIGRFAMs:TIGR01242UniGene:At.11513UniProt:Q9SEI2
Coordinates (TAIR10) chr3:+:1603540..1605993
Molecular Weight (calculated) 47482.80 Da
IEP (calculated) 4.65
GRAVY (calculated) -0.44
Length 424 amino acids
Sequence (TAIR10)
(BLAST)
001: MATPMVEDTS SFEEDQLASM STEDITRATR LLDNEIRILK EDAQRTNLEC DSYKEKIKEN QEKIKLNKQL PYLVGNIVEI LEMNPEDDAE EDGANIDLDS
101: QRKGKCVVLK TSTRQTIFLP VVGLVDPDSL KPGDLVGVNK DSYLILDTLP SEYDSRVKAM EVDEKPTEDY NDIGGLEKQI QELVEAIVLP MTHKERFEKL
201: GVRPPKGVLL YGPPGTGKTL MARACAAQTN ATFLKLAGPQ LVQMFIGDGA KLVRDAFQLA KEKAPCIIFI DEIDAIGTKR FDSEVSGDRE VQRTMLELLN
301: QLDGFSSDER IKVIAATNRA DILDPALMRS GRLDRKIEFP HPTEEARARI LQIHSRKMNV HPDVNFEELA RSTDDFNGAQ LKAVCVEAGM LALRRDATEV
401: NHEDFNEGII QVQAKKKASL NYYA
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)