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AT2G39660.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plasma membrane 1.000
ASURE: plasma membrane
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : botrytis-induced kinase1
Curator
Summary (TAIR10)
Encodes a plasma membrane-localized ser/thr protein kinase that is a crucial component of host response signaling required to activate the resistance responses to Botrytis and A. brassicicola infection. It is likely a negative regulator of salicylic acid accumulation and basal defense against virulent bacterial pathogens.
Computational
Description (TAIR10)
botrytis-induced kinase1 (BIK1); FUNCTIONS IN: kinase activity; INVOLVED IN: protein amino acid autophosphorylation, defense response to fungus, N-terminal protein myristoylation, response to fungus; LOCATED IN: nucleolus, nucleus, plasma membrane, cytoplasm; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: PBS1-like 1 (TAIR:AT3G55450.1); Has 116707 Blast hits to 115355 proteins in 4256 species: Archae - 101; Bacteria - 13366; Metazoa - 43229; Fungi - 9583; Plants - 33164; Viruses - 356; Other Eukaryotes - 16908 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT2G39660-MONOMERBioGrid:3887DIP:DIP-51510NEC:2.7.11.1
eggNOG:COG0515eggNOG:KOG1187EMBL:AC003674EMBL:AC004218
EMBL:AF325086EMBL:AY062493EMBL:AY065029EMBL:AY093278
EMBL:AY093997EMBL:CP002685EnsemblPlants:AT2G39660EnsemblPlants:AT2G39660.1
entrez:818549Gene3D:2.60.120.200GeneID:818549Genevisible:O48814
GO:GO:0004674GO:GO:0005524GO:GO:0005634GO:GO:0005730
GO:GO:0005737GO:GO:0005886GO:GO:0009620GO:GO:0016301
GO:GO:0046777GO:GO:0050832GO:GO:0052033Gramene:AT2G39660.1
hmmpanther:PTHR27001hmmpanther:PTHR27001:SF124HOGENOM:HOG000116550InParanoid:O48814
IntAct:O48814InterPro:IPR000719InterPro:IPR001245InterPro:IPR008271
InterPro:IPR011009InterPro:IPR013320InterPro:IPR017441iPTMnet:O48814
KEGG:ath:AT2G39660OMA:HNGKSSDPaxDb:O48814Pfam:O48814
Pfam:PF07714Pfscan:PS50011PhylomeDB:O48814PIR:T00574
PRIDE:O48814PRO:PR:O48814PROSITE:PS00107PROSITE:PS00108
PROSITE:PS50011ProteinModelPortal:O48814Proteomes:UP000006548RefSeq:NP_181496.1
scanprosite:PS00107scanprosite:PS00108SMART:SM00220SMR:O48814
STRING:3702.AT2G39660.1SUPFAM:SSF56112TAIR:AT2G39660tair10-symbols:BIK1
UniGene:At.21254UniProt:O48814
Coordinates (TAIR10) chr2:+:16531943..16533601
Molecular Weight (calculated) 44099.90 Da
IEP (calculated) 9.79
GRAVY (calculated) -0.34
Length 395 amino acids
Sequence (TAIR10)
(BLAST)
001: MGSCFSSRVK ADIFHNGKSS DLYGLSLSSR KSSSTVAAAQ KTEGEILSST PVKSFTFNEL KLATRNFRPD SVIGEGGFGC VFKGWLDEST LTPTKPGTGL
101: VIAVKKLNQE GFQGHREWLT EINYLGQLSH PNLVKLIGYC LEDEHRLLVY EFMQKGSLEN HLFRRGAYFK PLPWFLRVNV ALDAAKGLAF LHSDPVKVIY
201: RDIKASNILL DADYNAKLSD FGLARDGPMG DLSYVSTRVM GTYGYAAPEY MSSGHLNARS DVYSFGVLLL EILSGKRALD HNRPAKEENL VDWARPYLTS
301: KRKVLLIVDN RLDTQYLPEE AVRMASVAVQ CLSFEPKSRP TMDQVVRALQ QLQDNLGKPS QTNPVKDTKK LGFKTGTTKS SEKRFTQKPF GRHLV
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)