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AT2G38170.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
vacuole 1.000
ASURE: vacuole
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:26748395 (2016): plant-type vacuole plant-type vacuole membrane
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:15539469 (2004): plant-type vacuole
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : cation exchanger 1
Curator
Summary (TAIR10)
Encodes a high affinity vacuolar calcium antiporter. The residue His 338 is critical to Ca2+ transport activity. Disruption of CAX1 reduces manganese and zinc of shoot tissue and results in a decrease in the activity of vacuolar V-type proton ATPase.
Computational
Description (TAIR10)
cation exchanger 1 (CAX1); FUNCTIONS IN: calcium:cation antiporter activity, calcium ion transmembrane transporter activity, calcium:hydrogen antiporter activity; INVOLVED IN: cold acclimation, response to salt stress, cellular zinc ion homeostasis, cellular manganese ion homeostasis, calcium ion transport; LOCATED IN: plant-type vacuole membrane, vacuolar membrane, vacuole, membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Sodium/calcium exchanger membrane region (InterPro:IPR004837), Calcium/proton exchanger superfamily (InterPro:IPR004798), Calcium/proton exchanger (InterPro:IPR004713); BEST Arabidopsis thaliana protein match is: cation exchanger 3 (TAIR:AT3G51860.1); Has 3042 Blast hits to 2882 proteins in 950 species: Archae - 18; Bacteria - 1703; Metazoa - 62; Fungi - 722; Plants - 217; Viruses - 0; Other Eukaryotes - 320 (source: NCBI BLink).
Protein Annotations
eggNOG:COG0387eggNOG:KOG1397EMBL:HE802833EMBL:HE802834
EMBL:HE802835EMBL:HE802836EMBL:HE802838EMBL:HE802839
EMBL:HE802840EMBL:HE802841EMBL:HE802842EMBL:HE802843
EMBL:HE802845EMBL:HE802847EMBL:HE802848EMBL:HE802849
EMBL:HE802850EnsemblPlants:AT2G38170EnsemblPlants:AT2G38170.1entrez:818395
ExpressionAtlas:M5BFB1GeneID:818395GO:GO:0015369GO:GO:0016021
Gramene:AT2G38170.1hmmpanther:PTHR31503hmmpanther:PTHR31503:SF1InterPro:IPR004713
InterPro:IPR004798InterPro:IPR004837KEGG:ath:AT2G38170KO:K07300
Pfam:PF01699Pfam:Q39253PhylomeDB:M5BFB1RefSeq:NP_181352.1
SMR:M5BFB1STRING:3702.AT2G38170.3tair10-symbols:ATCAX1tair10-symbols:CAX1
tair10-symbols:RCI4TIGRfam:TIGR00378TIGRfam:TIGR00846TIGRFAMs:TIGR00378
TIGRFAMs:TIGR00846TMHMM:TMhelixUniGene:At.12459UniProt:M5BFB1
UniProt:Q39253
Coordinates (TAIR10) chr2:-:15989429..15993178
Molecular Weight (calculated) 50179.70 Da
IEP (calculated) 6.16
GRAVY (calculated) 0.60
Length 463 amino acids
Sequence (TAIR10)
(BLAST)
001: MAGIVTEPWS VAENGNPSIT AKGSSRELRL GRTAHNMSSS SLRKKSDLRV IQKVPYKGLK DFLSNLQEVI LGTKLAILFP AIPAAIICTY CGVSQPWIFG
101: LSLLGLTPLA ERVSFLTEQL AFYTGPTLGG LLNATCGNAT ELIIAILALT NNKVAVVKYS LLGSILSNLL LVLGTSLFCG GIANIRREQR FDRKQADVNF
201: FLLLLGFLCH LLPLLVGYLK NGEASAAVLS DMQLSISRGF SIVMLISYIA YLVFQLWTHR QLFDAQEQED EYDDDVEQET AVISFWSGFA WLVGMTLVIA
301: LLSEYVVATI EEASDKWNLS VSFISIILLP IVGNAAEHAG AVIFAFKNKL DISLGVALGS ATQIGLFVVP LTIIVAWILG INMDLNFGPL ETGCLAVSII
401: ITAFTLQDGS SHYMKGLVLL LCYFIIAICF FVDKLPQKQN AIHLGHQAMN NVVTATGGGV FSS
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)