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AT1G72050.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : transcription factor IIIA
Curator
Summary (TAIR10)
Encodes a transcriptional factor TFIIIA required for transcription of 5S rRNA gene. 5S rRNA is the smallest constituent of the ribosome. Work on one of the gene models AT1G72050.2 showed that it encodes a protein with nine Cys(2)-His(2)-type zinc fingers, a characteristic feature of TFIIIA proteins. AT1G72050.2 also contains a 23 amino acid spacer between fingers 1 and 2, a 66 amino acid spacer between fingers 4 and 5, and a 50 amino acid non-finger C-terminal tail. in vitro assay demonstrated that AT1g72050.2 binds to 5S rDNA and efficiently stimulates the transcription of 5S rRNA. AT1g72050.2 also binds to 5S rRNA in vitro. AT1g72050.2 is located at several nuclear foci including the nucleolus and is absent from the cytoplasm.
Computational
Description (TAIR10)
transcription factor IIIA (TFIIIA); FUNCTIONS IN: zinc ion binding, nucleic acid binding; INVOLVED IN: biological_process unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, C2H2-like (InterPro:IPR015880), Zinc finger, C2H2-type (InterPro:IPR007087), Zinc finger, C2H2-type/integrase, DNA-binding (InterPro:IPR013087); BEST Arabidopsis thaliana protein match is: relative of early flowering 6 (TAIR:AT3G48430.1); Has 65581 Blast hits to 29235 proteins in 482 species: Archae - 0; Bacteria - 31; Metazoa - 61143; Fungi - 1878; Plants - 364; Viruses - 2; Other Eukaryotes - 2163 (source: NCBI BLink).
Protein Annotations
eggNOG:COG5048eggNOG:KOG1721EMBL:AC069273EMBL:AJ630478
EMBL:AY054225EMBL:AY066042EMBL:AY186610EMBL:AY568650
EMBL:CP002684EnsemblPlants:AT1G72050EnsemblPlants:AT1G72050.1EnsemblPlants:AT1G72050.2
entrez:843536ExpressionAtlas:Q84MZ4Gene3D:3.30.160.60GeneID:843536
GO:GO:0003700GO:GO:0003723GO:GO:0005634GO:GO:0005730
GO:GO:0006351GO:GO:0007275GO:GO:0008097GO:GO:0046872
GO:GO:0080084hmmpanther:PTHR24375hmmpanther:PTHR24375:SF106HOGENOM:HOG000238731
IntAct:Q84MZ4InterPro:IPR007087InterPro:IPR013087InterPro:IPR015880
OMA:TCYVDDCPaxDb:Q84MZ4Pfscan:PS50157PhylomeDB:Q84MZ4
PIR:F96743PROSITE:PS00028PROSITE:PS50157ProteinModelPortal:Q84MZ4
Proteomes:UP000006548Reactome:R-ATH-76061RefSeq:NP_565033.1RefSeq:NP_974128.1
scanprosite:PS00028SMART:SM00355SMR:Q84MZ4STRING:3702.AT1G72050.2
SUPFAM:SSF57667TAIR:AT1G72050tair10-symbols:TFIIIAUniGene:At.17480
UniGene:At.66854UniProt:Q940P2
Coordinates (TAIR10) chr1:+:27115808..27117228
Molecular Weight (calculated) 36528.70 Da
IEP (calculated) 8.02
GRAVY (calculated) -1.07
Length 324 amino acids
Sequence (TAIR10)
(BLAST)
001: MFERSFTCYV DDCAASYRRK DHLNRHLLTH KGKLFKCPKE NCKSEFSVQG NVGRHVKKYH SNDNRDKDNT GLGDGDKDNT CKGDDDKEKS GSGGCEKENE
101: GNGGSGKDNN GNGDSQPAEC STGQKQVVCK EIGCGKAFKY PSQLQKHQDS HVKLDSVEAF CSEPGCMKYF TNEECLKSHI RSCHQHINCE ICGSKHLKKN
201: IKRHLRTHDE DSSPGEIKCE VEGCSSTFSK ASNLQKHMKA VHDDIRPFVC GFPGCGMRFA YKHVRNKHEN SGYHVYTCGD FVETDEDFTS RPRGGLKRKQ
301: VTAEMLVRKR VMPPRFDAEE HETC
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)