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AT1G49630.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
mitochondrion 0.500
plastid 0.500
ASURE: mitochondrion,plastid
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : presequence protease 2
Curator
Summary (TAIR10)
Zinc metalloprotease pitrilysin subfamily A. Signal peptide degrading enzyme targeted to mitochondria and chloroplasts. Expressed in flower, leaf and root. Not expressed in silique and shoot.
Computational
Description (TAIR10)
presequence protease 2 (PREP2); FUNCTIONS IN: metallopeptidase activity, metalloendopeptidase activity, zinc ion binding, catalytic activity, metal ion binding; INVOLVED IN: proteolysis, protein maturation by peptide bond cleavage; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase M16, C-terminal (InterPro:IPR007863), Peptidase M16C associated (InterPro:IPR013578), Peptidase M16, N-terminal (InterPro:IPR011765), Metalloenzyme, LuxS/M16 peptidase-like, metal-binding (InterPro:IPR011249), Peptidase M16, core (InterPro:IPR011237); BEST Arabidopsis thaliana protein match is: presequence protease 1 (TAIR:AT3G19170.1); Has 3964 Blast hits to 3937 proteins in 1352 species: Archae - 7; Bacteria - 2621; Metazoa - 205; Fungi - 264; Plants - 79; Viruses - 0; Other Eukaryotes - 788 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:GQT-933-MONOMERBioCyc:ARA:GQT-934-MONOMERBioCyc:ARA:GQT-935-MONOMERBioGrid:26612
EC:3.4.24.-eggNOG:COG1026eggNOG:KOG2019EMBL:AC011807
EMBL:AY074305EMBL:BT004376EMBL:CP002684EnsemblPlants:AT1G49630
EnsemblPlants:AT1G49630.1EnsemblPlants:AT1G49630.2EnsemblPlants:AT1G49630.3entrez:841387
Gene3D:3.30.830.10GeneID:841387Genevisible:Q8VY06GO:GO:0004222
GO:GO:0005739GO:GO:0005759GO:GO:0008270GO:GO:0009507
GO:GO:0009570GO:GO:0016485Gramene:AT1G49630.1Gramene:AT1G49630.2
Gramene:AT1G49630.3hmmpanther:PTHR11851hmmpanther:PTHR11851:SF68HOGENOM:HOG000008829
InParanoid:Q8VY06InterPro:IPR007863InterPro:IPR011237InterPro:IPR011249
InterPro:IPR011765InterPro:IPR013578KEGG:ath:AT1G49630KO:K06972
MEROPS:M16.018ncoils:CoilOMA:PSEDITYPaxDb:Q8VY06
Pfam:PF00675Pfam:PF05193Pfam:PF08367Pfam:Q8VY06
PhylomeDB:Q8VY06PIR:A96533PRIDE:Q8VY06PRO:PR:Q8VY06
ProteinModelPortal:Q8VY06Proteomes:UP000006548RefSeq:NP_175386.2RefSeq:NP_850961.1
RefSeq:NP_850962.1SMART:SM01264SMR:Q8VY06STRING:3702.AT1G49630.1
SUPFAM:SSF63411TAIR:AT1G49630tair10-symbols:ATPREP2tair10-symbols:PREP2
UniGene:At.27723UniProt:Q8VY06
Coordinates (TAIR10) chr1:-:18368405..18375336
Molecular Weight (calculated) 121138.00 Da
IEP (calculated) 5.14
GRAVY (calculated) -0.36
Length 1080 amino acids
Sequence (TAIR10)
(BLAST)
0001: MLRSLTCSST ITSTSLFFRS FRQLPRSYLS PSSSTTVVGA SGRNIRRLST LEAAGRRLFL RRGLKLLSAA SRGLNGQFSR LSIRAVATQS APSSYPGQDE
0101: AEKLGFEKVS EEFISECKSK AVLFKHKKTG CEVMSVSNDD ENKVFGIVFR TPPKDSTGIP HILEHSVLCG SRKYPMKEPF VELLKGSLHT FLNAFTYPDR
0201: TCYPVASTNK KDFYNLVDVY LDAVFFPKCV DDVHTFQQEG WHYELNDPSE DISYKGVVFN EMKGVYSQPD NILGRVTQQA LCPENTYGVD SGGDPKDIPK
0301: LTFEKFKEFH RQYYHPSNAR IWFYGDDDPV HRLRVLSEYL DMFDASPARD SSKVEPQKLF SRPRRIVEKY PAGEDGDLKK KHMVCLNWLL SDKPLDLQTQ
0401: LALGFLDHLM LGTPASPLRK ILLESGLGEA LVNSGMEDEL LQPQFSIGLK GVSDDNVQKV EELVMNTLRK LADEGFDTDA VEASMNTIEF SLRENNTGSS
0501: PRGLSLMLQS IAKWIYDMDP FEPLKYEEPL KSLKARIAEK GSKSVFSPLI EEYILNNPHC VTIEMQPDPE KASLEEAEEK SILEKVKASM TEEDLTELAR
0601: ATEELRLKQE TPDPPDALKC VPSLNLSDIP KEPIYVPTEV GDINGVKVLR NDLFTNNILY TEVVFDMGSV KHELLQLIPL FCQSLLEMGT QDLTFVQLNQ
0701: LIGRKTGGIS VYPLTSSVYG RDDPCSKIIV RGKSMVGRAE DLFNLMNCVL QEVRFTDQQR FKQFVSQSRA RMENRLRGSG QGIAAARMDA MLNVAGWMSE
0801: QMGGLSYLEF LHTLEQKVDQ DWEGISSSLE EIRRSFLSRN GCIVNMTADG KSLTNTEKYV GKFLDLLPEN PSGELVTWDA RLPLRNEAIV IPTQVNYVGK
0901: AGNIYSSGYK LDGSSYVISK HISNTWLWDR VRVSGGAYGG SCDFDSHSGV FSFLSYRDPN LLKTLDIYDG TGDFLRGLDV DEDTLTKAII GTIGDVDSYQ
1001: LPDAKGYTSL LRHLLNVTDE ERQIRREEIL STSLKDFKEF AEAIDSVSDK GVAVAVASQE DIDAANRERS NFFEVKKAAL
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)